PIPA5118747

Phospho-p130 (Thr642) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5118747-Each-of-1 In Stock ₹ 41,539.38

PIPA5118747 - Each of 1

₹ 41,539.38

In Stock

Quantity

1

Base Price: ₹ 41,539.38

GST (18%): ₹ 7,477.088

Total Price: ₹ 49,016.468

Antigen

Phospho-p130 (Thr642)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

RBL2

Gene Alias

130 kDa retinoblastoma-associated protein; FLJ26459; p130; PPAR-alpha-interacting complex protein 128; PRB2; PRIC128; RB transcriptional corepressor like 2; Rb2; rb2 p130; Rbl2; RBR-2; retinoblastoma-like 2; retinoblastoma-like 2 (p130); retinoblastoma-like protein 2; Retinoblastoma-related protein 2

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

19651, 5934, 81758

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O55081, Q08999, Q64700

Gene Symbols

RBL2

Immunogen

A synthesized peptide derived from human RBL2(Accession Q08999), corresponding to amino acid residues around phosphorylated Thr642.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of RBL2 only when phosphorylated at Thr642
  • RBL2 (also known as p130) or Retinoblastoma-like protein 2 is a key regulator of entry into cell division
  • It is directly involved in heterochromatin formation by maintaining overall chromatin structure and (in particular) that of constitutive heterochromatin by stabilizing histone methylation
  • RBL2 recruits and targets histone methyltransferases KMT5B and KMT5C leading to epigenetic transcriptional repression
  • It controls histone H4 'Lys20' trimethylation
  • It probably also acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters
  • RBL2 serves as a potent inhibitor of E2F-mediated trans-activation and associates preferentially with E2F5.

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Img

Thermo Scientific

PIPA5118747

--


Antigen:
Phospho-p130 (Thr642)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RBL2

Gene Alias:
130 kDa retinoblastoma-associated protein; FLJ26459; p130; PPAR-alpha-interacting complex protein 128; PRB2; PRIC128; RB transcriptional corepressor like 2; Rb2; rb2 p130; Rbl2; RBR-2; retinoblastoma-like 2; retinoblastoma-like 2 (p130); retinoblastoma-like protein 2; Retinoblastoma-related protein 2

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19651, 5934, 81758

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O55081, Q08999, Q64700

Gene Symbols:
RBL2

Immunogen:
A synthesized peptide derived from human RBL2(Accession Q08999), corresponding to amino acid residues around phosphorylated Thr642.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5118748

--


Antigen:
Phospho-p130 (Ser639)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RBL2

Gene Alias:
130 kDa retinoblastoma-associated protein; FLJ26459; p130; PPAR-alpha-interacting complex protein 128; PRB2; PRIC128; RB transcriptional corepressor like 2; Rb2; rb2 p130; Rbl2; RBR-2; retinoblastoma-like 2; retinoblastoma-like 2 (p130); retinoblastoma-like protein 2; Retinoblastoma-related protein 2

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19651, 5934, 81758

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O55081, Q08999, Q64700

Gene Symbols:
RBL2

Immunogen:
A synthesized peptide derived from human RBL2(Accession Q08999), corresponding to amino acid residues around phosphorylated Ser639.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5118753

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Antigen:
Phospho-EphA2 (Tyr930)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EPHA2

Gene Alias:
ARCC2; AW545284; CTPA; CTPP1; CTRCT6; Eck; EPH receptor A2; Epha2; ephrin receptor EphA2; Ephrin type-A receptor 2; Epithelial cell kinase; epithelial cell receptor protein tyrosine kinase; I79_019726; Myk2; Sek2; Sek-2; soluble EPHA2 variant 1; tyrosine-protein kinase receptor ECK; Tyrosine-protein kinase receptor MPK-5; tyrosine-protein kinase receptor SEK-2

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13836, 1969, 366492

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P29317, Q03145

Gene Symbols:
EPHA2

Immunogen:
A synthesized peptide derived from human EPHA2(Accession P29317), corresponding to amino acid residues around phosphorylated Tyr930.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5118755

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Antigen:
Phospho-EphA5 (Tyr650)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EPHA5

Gene Alias:
AI854630; ARCC2; AW125296; brain-specific kinase; BSK; CEK7; CEK-7; CTPA; CTPP1; ECK; eck-like sequence 1; EHK1; EHK-1; EK7; Ekh1; Els1; Els1.; epa5; EPH homology kinase 1; Eph receptor A5; EPHA5; EPH-like kinase 7; Ephrin A2; Ephrin A5; Ephrin type-A receptor 5; EphrinA2; EphrinA5; HEK7; receptor protein-tyrosine kinase HEK7; Rek7; TYRO4; tyrosine-protein kinase receptor EHK-1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13839, 2044, 79208

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P54756, P54757, Q60629

Gene Symbols:
EPHA5

Immunogen:
A synthesized peptide derived from human EPHA5(Accession P54756), corresponding to amino acid residues around phosphorylated Tyr650.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG