PIPA5118723
Phospho-TSC2 (Ser981) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5118723-Each-of-1 | In Stock | ₹ 41,539.38 |
PIPA5118723 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,539.38
GST (18%): ₹ 7,477.088
Total Price: ₹ 49,016.468
Antigen
Phospho-TSC2 (Ser981)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TSC2
Gene Alias
LAM; Nafld; OTTHUMP00000198394; PPP1R160; protein phosphatase 1, regulatory subunit 160; Rc; renal carcinoma; Tcs2; Tsc2; TSC4; Tuberin; tuberous sclerosis 2; tuberous sclerosis 2 homolog protein; tuberous sclerosis 2 protein; Tuberous sclerosis 2 protein homolog
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
22084, 24855, 7249
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P49815, P49816, Q61037
Gene Symbols
TSC2
Immunogen
A synthesized peptide derived from human TSC2(Accession P49815), corresponding to amino acid residues around phosphorylated Ser981.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of Tuberin/TSC2 only when phosphorylated at Ser981
- TSC2 (Tuberin, Tuberous sclerosis complex, TSC Complex Subunit 2), is implicated as a tumor suppressor and may function in vesicular transport, play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors
- TSC2 associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin
- Phosphorylation of tuberin on Ser 939 and Thr 1462 regulates its interaction with hamartin, and is stimulated by various growth factors through the phosphoinositide 3-kinase/Akt pathway
- TSC2 may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors
- Interaction between TSC1 and TSC2 may facilitate vesicular docking
- TSC2 specifically stimulates the intrinsic GTPase activity of the Ras related protein RAP1A and RAB5, suggesting a possible mechanism for its role in regulating cellular growth
- Mutations in TSC2 lead to constitutive activation of RAP1A in tumors and are involved in diseases such as lymphangioleiomyomatosis and TSC2 angiomyolipoma
- Alternative splicing results in transcript variants of three different isoforms of TSC2.
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Antigen: Phospho-TSC2 (Ser981)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TSC2
Gene Alias: LAM; Nafld; OTTHUMP00000198394; PPP1R160; protein phosphatase 1, regulatory subunit 160; Rc; renal carcinoma; Tcs2; Tsc2; TSC4; Tuberin; tuberous sclerosis 2; tuberous sclerosis 2 homolog protein; tuberous sclerosis 2 protein; Tuberous sclerosis 2 protein homolog
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22084, 24855, 7249
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P49815, P49816, Q61037
Gene Symbols: TSC2
Immunogen: A synthesized peptide derived from human TSC2(Accession P49815), corresponding to amino acid residues around phosphorylated Ser981.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-TSC2 (Ser981)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TSC2
Gene Alias:
LAM; Nafld; OTTHUMP00000198394; PPP1R160; protein phosphatase 1, regulatory subunit 160; Rc; renal carcinoma; Tcs2; Tsc2; TSC4; Tuberin; tuberous sclerosis 2; tuberous sclerosis 2 homolog protein; tuberous sclerosis 2 protein; Tuberous sclerosis 2 protein homolog
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22084, 24855, 7249
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P49815, P49816, Q61037
Gene Symbols:
TSC2
Immunogen:
A synthesized peptide derived from human TSC2(Accession P49815), corresponding to amino acid residues around phosphorylated Ser981.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-Cyclin E (Ser399)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CCNE1
Gene Alias: AW538188; Ccne; Ccne1; CycE1; CYCLE; cyclin E; cyclin E1; cyclin Es; cyclin Et; E-S; G1/S-specific cyclin-E1; pCCNE1
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12447, 25729, 898
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P24864, P39949, Q61457
Gene Symbols: CCNE1
Immunogen: A synthesized peptide derived from human CCNE1(Accession P24864), corresponding to amino acid residues around phosphorylated Ser399.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-Cyclin E (Ser399)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CCNE1
Gene Alias:
AW538188; Ccne; Ccne1; CycE1; CYCLE; cyclin E; cyclin E1; cyclin Es; cyclin Et; E-S; G1/S-specific cyclin-E1; pCCNE1
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12447, 25729, 898
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P24864, P39949, Q61457
Gene Symbols:
CCNE1
Immunogen:
A synthesized peptide derived from human CCNE1(Accession P24864), corresponding to amino acid residues around phosphorylated Ser399.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-PRK1/PRK2 (Thr774, Thr816)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PKN2
Gene Alias: 6030436C20Rik; AI507382; cardiolipin-activated protein kinase Pak2; DBK; F730027O18Rik; p140 kinase; PAK1; PAK-1; PAK2; Pak-2; Pkn; PKN gamma; Pkn1; Pkn2; PKN-ALPHA; Prk1; Prk2; Prkcl1; PRKCL2; PRO2042; protease-activated kinase 1; protease-activated kinase 2; protein kinase C-like 1; Protein kinase C-like 2; protein kinase C-like PKN; protein kinase C-related kinase 1; protein kinase N1; protein kinase N2; protein kinase PKN; protein kinase PKN-alpha; Protein-kinase C-related kinase 1; protein-kinase C-related kinase 2; serine/threonine kinase 3; serine/threonine kinase 7; serine/threonine protein kinase N; serine/threonine-protein kinase N1; Serine/threonine-protein kinase N2; serine-threonine kinase N; serine-threonine protein kinase N; Stk3; Stk7
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 207122, 29355, 5585, 5586
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: O08874, Q16512, Q16513, Q63433
Gene Symbols: PKN1, PKN2
Immunogen: A synthesized peptide derived from human PKN1(Accession Q16512), corresponding to amino acid residues around phosphorylated Thr774.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-PRK1/PRK2 (Thr774, Thr816)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PKN2
Gene Alias:
6030436C20Rik; AI507382; cardiolipin-activated protein kinase Pak2; DBK; F730027O18Rik; p140 kinase; PAK1; PAK-1; PAK2; Pak-2; Pkn; PKN gamma; Pkn1; Pkn2; PKN-ALPHA; Prk1; Prk2; Prkcl1; PRKCL2; PRO2042; protease-activated kinase 1; protease-activated kinase 2; protein kinase C-like 1; Protein kinase C-like 2; protein kinase C-like PKN; protein kinase C-related kinase 1; protein kinase N1; protein kinase N2; protein kinase PKN; protein kinase PKN-alpha; Protein-kinase C-related kinase 1; protein-kinase C-related kinase 2; serine/threonine kinase 3; serine/threonine kinase 7; serine/threonine protein kinase N; serine/threonine-protein kinase N1; Serine/threonine-protein kinase N2; serine-threonine kinase N; serine-threonine protein kinase N; Stk3; Stk7
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
207122, 29355, 5585, 5586
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O08874, Q16512, Q16513, Q63433
Gene Symbols:
PKN1, PKN2
Immunogen:
A synthesized peptide derived from human PKN1(Accession Q16512), corresponding to amino acid residues around phosphorylated Thr774.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-Caspase 3 (Ser26)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CASP3
Gene Alias: A830040C14Rik; AC-3; Apopain; Apopain precursor; Casp3; CASP-3; caspase 3; Caspase 3 apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis related cysteine protease; Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis-related cysteine peptidase; caspase 3, apoptosis-related cysteine protease; Caspase3; caspase-3; Caspase-3 subunit p12; Caspase-3 subunit p17; Caspase-3-like protein; CC3; Cpp32; CPP-32; CPP32B; CPP32beta; cysteine protease CPP32; cysteine protease; CPP32; apopain; ICE3; IRP; LICE; mLdy; PARP cleavage protease; procaspase3; protein Yama; SCA-1; SREBP cleavage activity 1; Yama; yama protein
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12367, 25402, 836
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P42574, P55213, P70677
Gene Symbols: CASP3
Immunogen: A synthesized peptide derived from human CASP3(Accession P42574), corresponding to amino acid residues around phosphorylated Ser26.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-Caspase 3 (Ser26)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CASP3
Gene Alias:
A830040C14Rik; AC-3; Apopain; Apopain precursor; Casp3; CASP-3; caspase 3; Caspase 3 apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis related cysteine protease; Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis-related cysteine peptidase; caspase 3, apoptosis-related cysteine protease; Caspase3; caspase-3; Caspase-3 subunit p12; Caspase-3 subunit p17; Caspase-3-like protein; CC3; Cpp32; CPP-32; CPP32B; CPP32beta; cysteine protease CPP32; cysteine protease; CPP32; apopain; ICE3; IRP; LICE; mLdy; PARP cleavage protease; procaspase3; protein Yama; SCA-1; SREBP cleavage activity 1; Yama; yama protein
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12367, 25402, 836
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P42574, P55213, P70677
Gene Symbols:
CASP3
Immunogen:
A synthesized peptide derived from human CASP3(Accession P42574), corresponding to amino acid residues around phosphorylated Ser26.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG