PIPA5120046
TSC2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5120046-Each-of-1 | In Stock | ₹ 44,811.50 |
PIPA5120046 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,811.50
GST (18%): ₹ 8,066.07
Total Price: ₹ 52,877.57
Antigen
TSC2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TSC2
Gene Alias
LAM; Nafld; OTTHUMP00000198394; PPP1R160; protein phosphatase 1, regulatory subunit 160; Rc; renal carcinoma; Tcs2; Tsc2; TSC4; Tuberin; tuberous sclerosis 2; tuberous sclerosis 2 homolog protein; tuberous sclerosis 2 protein; Tuberous sclerosis 2 protein homolog
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
7249
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.55 mg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Accession No.
P49815
Gene Symbols
TSC2
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1160-1255 of human TSC2 (NP_000539.2).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive test controls include: SH-SY5Y
- The target is usually found in the following locations: Cytoplasm, Membrane, Peripheral membrane protein
- Immunogen sequence: TAPAAKPEKA SAGTRVPVQE KTNLAAYVPL LTQGWAEILV RRPTGNTSWL MSLENPLSPF SSDINNMPLQ ELSNALMAAE RFKEHRDTAL YKSLSV TSC2 (Tuberin, Tuberous sclerosis complex, TSC Complex Subunit 2), is implicated as a tumor suppressor and may function in vesicular transport, play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors
- TSC2 associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin
- Phosphorylation of tuberin on Ser 939 and Thr 1462 regulates its interaction with hamartin, and is stimulated by various growth factors through the phosphoinositide 3-kinase/Akt pathway
- TSC2 may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors
- Interaction between TSC1 and TSC2 may facilitate vesicular docking
- TSC2 specifically stimulates the intrinsic GTPase activity of the Ras related protein RAP1A and RAB5, suggesting a possible mechanism for its role in regulating cellular growth
- Mutations in TSC2 lead to constitutive activation of RAP1A in tumors and are involved in diseases such as lymphangioleiomyomatosis and TSC2 angiomyolipoma
- Alternative splicing results in transcript variants of three different isoforms of TSC2.
Compare Similar Items
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Antigen: TSC2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TSC2
Gene Alias: LAM; Nafld; OTTHUMP00000198394; PPP1R160; protein phosphatase 1, regulatory subunit 160; Rc; renal carcinoma; Tcs2; Tsc2; TSC4; Tuberin; tuberous sclerosis 2; tuberous sclerosis 2 homolog protein; tuberous sclerosis 2 protein; Tuberous sclerosis 2 protein homolog
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7249
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.55 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Accession No.: P49815
Gene Symbols: TSC2
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1160-1255 of human TSC2 (NP_000539.2).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TSC2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TSC2
Gene Alias:
LAM; Nafld; OTTHUMP00000198394; PPP1R160; protein phosphatase 1, regulatory subunit 160; Rc; renal carcinoma; Tcs2; Tsc2; TSC4; Tuberin; tuberous sclerosis 2; tuberous sclerosis 2 homolog protein; tuberous sclerosis 2 protein; Tuberous sclerosis 2 protein homolog
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7249
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.55 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Accession No.:
P49815
Gene Symbols:
TSC2
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1160-1255 of human TSC2 (NP_000539.2).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: SSB
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SSB
Gene Alias: autoantigen La; La; la autoantigen; La autoantigen homolog; La protein; la ribonucleoprotein; La ribonucleoprotein domain family, member 3; La/SSB; LARP3; lupus La antigen; lupus La protein; Lupus La protein homolog; Lupus LA protein homolog (LA ribonucleoprotein) (LA autoantigen homolog); lupus La protein-like; mRNA for autoantigen; OTTHUMP00000204777; sjoegren syndrome type B antigen; Sjogren syndrome antigen B; Sjogren syndrome antigen B (autoantigen La); small RNA binding exonuclease protection factor La; Ssb; SS-B; SS-B/La protein
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 6741
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 4.89 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P05455
Gene Symbols: SSB
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 166-408 of human SSB (NP_003133.1).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
SSB
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SSB
Gene Alias:
autoantigen La; La; la autoantigen; La autoantigen homolog; La protein; la ribonucleoprotein; La ribonucleoprotein domain family, member 3; La/SSB; LARP3; lupus La antigen; lupus La protein; Lupus La protein homolog; Lupus LA protein homolog (LA ribonucleoprotein) (LA autoantigen homolog); lupus La protein-like; mRNA for autoantigen; OTTHUMP00000204777; sjoegren syndrome type B antigen; Sjogren syndrome antigen B; Sjogren syndrome antigen B (autoantigen La); small RNA binding exonuclease protection factor La; Ssb; SS-B; SS-B/La protein
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
6741
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
4.89 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P05455
Gene Symbols:
SSB
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 166-408 of human SSB (NP_003133.1).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Nrf2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NFE2L2
Gene Alias: AI194320; E4TF1-60; E4TF1A; HEBP1; Nfe2l2; NF-E2-related factor 2; NFE2-related factor 2; NF-E2-related factor-2; NFT2; NRF2; NRF2A; nuclear factor (erythroid-derived 2)-like 2; nuclear factor erythroid 2-like 2; nuclear factor erythroid 2-related factor 2; nuclear factor erythroid-derived 2-like 2; nuclear factor, erythroid 2 like 2; nuclear factor, erythroid 2-like 2; nuclear factor, erythroid derived 2, like 2; Unknown (protein for IMAGE:7945830)
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18024, 4780, 83619
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.13 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Accession No.: O54968, Q16236, Q60795
Gene Symbols: NFE2L2
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 243-400 of human NRF2 (NP_0061552)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Nrf2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NFE2L2
Gene Alias:
AI194320; E4TF1-60; E4TF1A; HEBP1; Nfe2l2; NF-E2-related factor 2; NFE2-related factor 2; NF-E2-related factor-2; NFT2; NRF2; NRF2A; nuclear factor (erythroid-derived 2)-like 2; nuclear factor erythroid 2-like 2; nuclear factor erythroid 2-related factor 2; nuclear factor erythroid-derived 2-like 2; nuclear factor, erythroid 2 like 2; nuclear factor, erythroid 2-like 2; nuclear factor, erythroid derived 2, like 2; Unknown (protein for IMAGE:7945830)
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18024, 4780, 83619
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.13 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Accession No.:
O54968, Q16236, Q60795
Gene Symbols:
NFE2L2
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 243-400 of human NRF2 (NP_0061552)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: C/EBP beta
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Cebpb
Gene Alias: AGP/EBP; C EBP; c/EBP beta; C/EBPb; C/EBPbeta; C/EBP-beta; C/EBP-related protein 2; CCAAT enhancer binding protein beta; CCAAT/enhancer binding protein (C/EBP), beta; CCAAT/enhancer binding protein beta; CCAAT/enhancer-binding protein beta; CEBPB; Crp2; Il6dbp; IL-6DBP; interleukin 6-dependent DNA-binding protein; interleukin-6-dependent-binding protein; LAP; LIP; Liver activator protein; Liver-enriched inhibitory protein; Liver-enriched transcriptional activator; Nfil6; Nf-il6; NF-M; nuclear factor NF-IL6; nuclear factor of interleukin 6; nuclear factor-IL6; nuclear protein Il6; OTTMUSP00000017503; PP9092; Sfb; SF-B; Silencer factor B; TCF5; TCF-5; transcription factor 5; transcription factor C/EBP beta
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1051, 12608, 24253
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.74 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.: P17676, P21272, P28033
Gene Symbols: Cebpb
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 171-216 of human C/EBPB (NP_0051852)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
C/EBP beta
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Cebpb
Gene Alias:
AGP/EBP; C EBP; c/EBP beta; C/EBPb; C/EBPbeta; C/EBP-beta; C/EBP-related protein 2; CCAAT enhancer binding protein beta; CCAAT/enhancer binding protein (C/EBP), beta; CCAAT/enhancer binding protein beta; CCAAT/enhancer-binding protein beta; CEBPB; Crp2; Il6dbp; IL-6DBP; interleukin 6-dependent DNA-binding protein; interleukin-6-dependent-binding protein; LAP; LIP; Liver activator protein; Liver-enriched inhibitory protein; Liver-enriched transcriptional activator; Nfil6; Nf-il6; NF-M; nuclear factor NF-IL6; nuclear factor of interleukin 6; nuclear factor-IL6; nuclear protein Il6; OTTMUSP00000017503; PP9092; Sfb; SF-B; Silencer factor B; TCF5; TCF-5; transcription factor 5; transcription factor C/EBP beta
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1051, 12608, 24253
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.74 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.:
P17676, P21272, P28033
Gene Symbols:
Cebpb
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 171-216 of human C/EBPB (NP_0051852)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG