PIPA5118507

DKC1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5118507-Each-of-1 In Stock ₹ 41,539.38

PIPA5118507 - Each of 1

₹ 41,539.38

In Stock

Quantity

1

Base Price: ₹ 41,539.38

GST (18%): ₹ 7,477.088

Total Price: ₹ 49,016.468

Antigen

DKC1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DKC1

Gene Alias

BC068171; CBF5; CBF5 homolog; DKC; DKC1; DKCX; dyskeratosis congenita 1, dyskerin; dyskeratosis congenita 1, dyskerin homolog; dyskerin; dyskerin pseudouridine synthase 1; H/ACA ribonucleoprotein complex subunit 4; H/ACA ribonucleoprotein complex subunit DKC1; Nap57; NOLA4; Nopp140-associated protein of 57 kDa; nucleolar protein family A member 4; Nucleolar protein NAP57; snoRNP protein DKC1; XAP101

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

170944, 1736, 245474

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O60832, P40615, Q9ESX5

Gene Symbols

DKC1

Immunogen

A synthesized peptide derived from human DKC1(Accession O60832), corresponding to amino acid residues R183-L233.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total DKC1
  • This gene is a member of the H/ACA snoRNPs gene family
  • snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA
  • The H/ACA snoRNPs also include the NOLA1, 2 and 3 proteins
  • The protein encoded by this gene and the three NOLA proteins localize to the dense fibrillar components of nucleoli and to coiled bodies in the nucleus
  • Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted
  • These four H/ACA snoRNP proteins are also components of the telomerase complex
  • The protein encoded by this gene is related to the Saccharomyces cerevisiae Cbf5p and Drosophila melanogaster Nop60B proteins
  • The gene lies in a tail-to-tail orientation with the palmitoylated erythrocyte membrane protein gene and is transcribed in a telomere to centromere direction
  • Both nucleotide substitutions and single trinucleotide repeat polymorphisms have been found in this gene
  • Mutations in this gene cause X-linked dyskeratosis congenita, a disease resulting in reticulate skin pigmentation, mucosal leukoplakia, nail dystrophy, and progressive bone marrow failure in most cases
  • Mutations in this gene also cause Hoyeraal-Hreidarsson syndrome, which is a more severe form of dyskeratosis congenita
  • Two transcript variants encoding different isoforms have been found for this gene.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5118507

--


Antigen:
DKC1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DKC1

Gene Alias:
BC068171; CBF5; CBF5 homolog; DKC; DKC1; DKCX; dyskeratosis congenita 1, dyskerin; dyskeratosis congenita 1, dyskerin homolog; dyskerin; dyskerin pseudouridine synthase 1; H/ACA ribonucleoprotein complex subunit 4; H/ACA ribonucleoprotein complex subunit DKC1; Nap57; NOLA4; Nopp140-associated protein of 57 kDa; nucleolar protein family A member 4; Nucleolar protein NAP57; snoRNP protein DKC1; XAP101

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
170944, 1736, 245474

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O60832, P40615, Q9ESX5

Gene Symbols:
DKC1

Immunogen:
A synthesized peptide derived from human DKC1(Accession O60832), corresponding to amino acid residues R183-L233.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5118508

--


Antigen:
ILKAP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ILKAP

Gene Alias:
0710007A14Rik; 1600009O09Rik; EC 3.1.3.16; ILK associated serine/threonine phosphatase; Ilkap; ILKAP2; ILKAP3; integrin-linked kinase associated phosphatase; integrin-linked kinase-associated serine/threonine phosphatase; integrin-linked kinase-associated serine/threonine phosphatase 2C; PP2Cdelta; PP2C-DELTA; PPM1O; protein phosphatase 2C; protein phosphatase 2c, delta isozyme; protein phosphatase, Mg2+/Mn2+ dependent 1O

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
64538, 67444, 80895

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8R0F6, Q9H0C8, Q9Z1Z6

Gene Symbols:
ILKAP

Immunogen:
A synthesized peptide derived from human ILKAP(Accession Q9H0C8), corresponding to amino acid residues L51-S101.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5118513

--


Antigen:
RAD18

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Rad18

Gene Alias:
2810024C04Rik; E3 ubiquitin-protein ligase RAD18; hHR18; hRAD18; mRAD18Sc; postreplication repair protein hRAD18p; postreplication repair protein RAD18; post-replication repair protein RAD18SC; Rad18; RAD18 E3 ubiquitin protein ligase; RAD18 homolog; RAD18 homolog (S. cerevisiae); RAD18, E3 ubiquitin protein ligase; RAD18, S. cerevisiae, homolog; Rad18sc; RING finger protein 73; RING-type E3 ubiquitin transferase RAD18; RNF73

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
362412, 56852

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9NS91

Gene Symbols:
Rad18

Immunogen:
A synthesized peptide derived from human RAD18(Accession Q9NS91), corresponding to amino acid residues N306-Q356.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5118514

--


Antigen:
GPR68

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GPR68

Gene Alias:
BB131428; Brgr1; Brgrb; G protein-coupled receptor 68; GPR12A; Gpr68; G-protein coupled receptor 68; Ogr1; OGR-1; ovarian cancer G protein-coupled receptor, 1; ovarian cancer G-protein coupled receptor 1; Sphingosylphosphorylcholine receptor

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
238377, 8111

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q15743, Q8BFQ3

Gene Symbols:
GPR68

Immunogen:
A synthesized peptide derived from human GPR68(Accession Q15743), corresponding to amino acid residues F194-Y244.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG