PIPA5118572
Phospho-IRF3 (Ser386) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5118572-Each-of-1 | In Stock | ₹ 41,539.38 |
PIPA5118572 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,539.38
GST (18%): ₹ 7,477.088
Total Price: ₹ 49,016.468
Antigen
Phospho-IRF3 (Ser386)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
IRF3
Gene Alias
C920001K05Rik; IIAE7; Interferon regulatory factor 3; IRF3; IRF-3; IRF3 (phospho S386); IRF3 (pS386); IRF3 (pSer386); IRF3 phospho; IRF3 phospho S386; IRF3 phospho Ser386; phospho IRF3
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
292892, 3661
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q14653
Gene Symbols
IRF3
Immunogen
A synthesized peptide derived from human IRF3(Accession Q14653), corresponding to amino acid residues around phosphorylated Ser386.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of IRF3 only when phosphorylated at Serine 386
- IFR3 (interferon regulatory factor 3) is a key transcriptional regulator of type I interferon (IFN)-dependent immune responses
- It plays a critical role in the innate immune response against DNA and RNA viruses
- IFR3 regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters
- It acts as a more potent activator of the IFN-beta gene than the IFN-alpha gene and plays a critical role in both the early and late phases of the IFNA/B gene induction
- IFR3 is found in an inactive form in the cytoplasm of uninfected cells and following viral infection, double-stranded RNA, or toll-like receptor signaling
- It is phosphorylated by IKBKE and TBK1 kinases
- This induces a conformational change, leading to its dimerization and nuclear localization and association with CREB binding protein to form dsRNA-activated factor 1 (DRAF1), a complex which activates the transcription of the type I IFN and ISG genes
- Mutations in the gene can result in encephalopathy, acute, infection-induced, herpes-specific 7.
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Antigen: Phospho-IRF3 (Ser386)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: IRF3
Gene Alias: C920001K05Rik; IIAE7; Interferon regulatory factor 3; IRF3; IRF-3; IRF3 (phospho S386); IRF3 (pS386); IRF3 (pSer386); IRF3 phospho; IRF3 phospho S386; IRF3 phospho Ser386; phospho IRF3
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 292892, 3661
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q14653
Gene Symbols: IRF3
Immunogen: A synthesized peptide derived from human IRF3(Accession Q14653), corresponding to amino acid residues around phosphorylated Ser386.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-IRF3 (Ser386)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IRF3
Gene Alias:
C920001K05Rik; IIAE7; Interferon regulatory factor 3; IRF3; IRF-3; IRF3 (phospho S386); IRF3 (pS386); IRF3 (pSer386); IRF3 phospho; IRF3 phospho S386; IRF3 phospho Ser386; phospho IRF3
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
292892, 3661
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q14653
Gene Symbols:
IRF3
Immunogen:
A synthesized peptide derived from human IRF3(Accession Q14653), corresponding to amino acid residues around phosphorylated Ser386.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-FGFR1/FGFR2 (Tyr463, Tyr466)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: FGFR2
Gene Alias: AU043015; AW208770; AW556123; bacteria-expressed kinase; basic fibroblast growth factor receptor 1; BBDS; BEK; BEK fibroblast growth factor receptor; BFGFR; bFGF-R; bFGF-R-1; BFR-1; CD331; CD332; CEK; CEK3; CFD1; c-fgr; Eask; ECCL; ECT1; FGF Receptor 2; FGF receptor-1; FGFBR; fgfr 1; Fgfr1; Fgfr-1; FGFR1/PLAG1 fusion; FGFR2; Fgfr-2; Fgfr7; Fgfr-7; Fibroblast growth factor receptor 1; fibroblast growth factor receptor 2; FLG; FLT2; FLT-2; Fms-like tyrosine kinase 2; fms-related tyrosine kinase 2; HBGFR; heparin-binding growth factor receptor; HH2; HRTFDS; Hspy; hydroxyaryl-protein kinase; JWS; KAL2; Keratinocyte growth factor receptor; KGFR; KGFRTr; KSAM; K-SAM; MFR; N-sam; OGD; protein tyrosine kinase, receptor like 14; proto-oncogene c-Fgr; Soluble KGFR; svs; TK14; TK25
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14182, 14183, 2260, 2263, 25022, 79114
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P11362, P16092, P21802, P21803, Q04589
Gene Symbols: FGFR1, FGFR2
Immunogen: A synthesized peptide derived from human FGFR1/2 around the phosphorylation site of Tyr463/466.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-FGFR1/FGFR2 (Tyr463, Tyr466)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
FGFR2
Gene Alias:
AU043015; AW208770; AW556123; bacteria-expressed kinase; basic fibroblast growth factor receptor 1; BBDS; BEK; BEK fibroblast growth factor receptor; BFGFR; bFGF-R; bFGF-R-1; BFR-1; CD331; CD332; CEK; CEK3; CFD1; c-fgr; Eask; ECCL; ECT1; FGF Receptor 2; FGF receptor-1; FGFBR; fgfr 1; Fgfr1; Fgfr-1; FGFR1/PLAG1 fusion; FGFR2; Fgfr-2; Fgfr7; Fgfr-7; Fibroblast growth factor receptor 1; fibroblast growth factor receptor 2; FLG; FLT2; FLT-2; Fms-like tyrosine kinase 2; fms-related tyrosine kinase 2; HBGFR; heparin-binding growth factor receptor; HH2; HRTFDS; Hspy; hydroxyaryl-protein kinase; JWS; KAL2; Keratinocyte growth factor receptor; KGFR; KGFRTr; KSAM; K-SAM; MFR; N-sam; OGD; protein tyrosine kinase, receptor like 14; proto-oncogene c-Fgr; Soluble KGFR; svs; TK14; TK25
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14182, 14183, 2260, 2263, 25022, 79114
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P11362, P16092, P21802, P21803, Q04589
Gene Symbols:
FGFR1, FGFR2
Immunogen:
A synthesized peptide derived from human FGFR1/2 around the phosphorylation site of Tyr463/466.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: NDUFA4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NDUFA4
Gene Alias: CI-9k; CI-MLRQ; Complex I 9kDa subunit; complex I-MLRQ; Cytochrome c oxidase subunit NDUFA4; EC 1.6.5.3; EC 1.6.99.3; MLRQ; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4 (9 kDa, MLRQ); NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4; NADH-ubiquinone oxidoreductase MLRQ subunit; NDUFA4; NDUFA4, mitochondrial complex associated
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17992, 4697, 681024
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: O00483, Q62425
Gene Symbols: NDUFA4
Immunogen: A synthesized peptide derived from human NDUFA4(Accession O00483), corresponding to amino acid residues N48-F81.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
NDUFA4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NDUFA4
Gene Alias:
CI-9k; CI-MLRQ; Complex I 9kDa subunit; complex I-MLRQ; Cytochrome c oxidase subunit NDUFA4; EC 1.6.5.3; EC 1.6.99.3; MLRQ; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4 (9 kDa, MLRQ); NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4; NADH-ubiquinone oxidoreductase MLRQ subunit; NDUFA4; NDUFA4, mitochondrial complex associated
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17992, 4697, 681024
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O00483, Q62425
Gene Symbols:
NDUFA4
Immunogen:
A synthesized peptide derived from human NDUFA4(Accession O00483), corresponding to amino acid residues N48-F81.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: ITGB5
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Itgb5
Gene Alias: [b]5; [b]-5; [b]5A; [b]5B; AA475909; AI874634; beta5; beta-5; CD61; ESTM23; FLJ26658; GP3A; GPIIIa; I79_000655; integrin beta 5; integrin beta-5; integrin subunit beta 5; integrin, beta 5; ITGB5; RGD1563276; testis secretory sperm-binding protein Li 217p
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16419, 257645, 3693
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: O70309, P18084
Gene Symbols: Itgb5
Immunogen: A synthesized peptide derived from human ITGB5(Accession P18084), corresponding to amino acid residues A726-K776.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ITGB5
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Itgb5
Gene Alias:
[b]5; [b]-5; [b]5A; [b]5B; AA475909; AI874634; beta5; beta-5; CD61; ESTM23; FLJ26658; GP3A; GPIIIa; I79_000655; integrin beta 5; integrin beta-5; integrin subunit beta 5; integrin, beta 5; ITGB5; RGD1563276; testis secretory sperm-binding protein Li 217p
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16419, 257645, 3693
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O70309, P18084
Gene Symbols:
Itgb5
Immunogen:
A synthesized peptide derived from human ITGB5(Accession P18084), corresponding to amino acid residues A726-K776.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG