PIPA5119048

Complement C9 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5119048-Each-of-1 In Stock ₹ 40,769.34

PIPA5119048 - Each of 1

₹ 40,769.34

In Stock

Quantity

1

Base Price: ₹ 40,769.34

GST (18%): ₹ 7,338.481

Total Price: ₹ 48,107.821

Antigen

Complement C9

Classification

Polyclonal

Conjugate

Unconjugated

Gene

C9

Gene Alias

ARMD15; C9; C9D; complement C9; complement component 9; complement component C9; Complement component C9a; Complement component C9b; complement protein C9; complement protein C9 precursor

Host Species

Guinea Pig

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100009197

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

500 μg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.

P48747

Gene Symbols

C9

Immunogen

Recombinant protein Complement Component 9. The antigen corresponds to amino acid range 139-519 of the target protein.

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Rabbit

Product Type

Antibody

Isotype

IgG

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Description

  • C5b-9 membrane attack complexes are assembled from five precursor molecules in the serum
  • Proteolytic cleavage of C5 by C5 convertase generates C5b which initiates assembly of the C5b-9 complex
  • The last step of C5b-9 complex formation involves polymerization of C9 which accompanies insertion of the complex into the cell membrane
  • During formation of C5b-8 and C9 polymerization, neoantigens are generated which are unique to the C5b-9 complex and are not present on any of the individual native complex components
  • The complement regulatory proteins CD59 and complement S-protein can both prevent C5b-9 insertion into the cell membrane
  • The formed SC5b-9 complex is unable to attach to cells and is cytolytically inactive
  • C5b-9 is involved in the progression of chronic proteinuric renal disease by mediating continuous tubulointerstitial damage
  • Early tubulointerstitial injury in the remnant kidney can be improved when C5b-9 complex forming is abrogated.

Compare Similar Items

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Img

Thermo Scientific

PIPA5119048

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Antigen:
Complement C9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
C9

Gene Alias:
ARMD15; C9; C9D; complement C9; complement component 9; complement component C9; Complement component C9a; Complement component C9b; complement protein C9; complement protein C9 precursor

Host Species:
Guinea Pig

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100009197

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P48747

Gene Symbols:
C9

Immunogen:
Recombinant protein Complement Component 9. The antigen corresponds to amino acid range 139-519 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Rabbit

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5119049

--


Antigen:
CPLX1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cplx1

Gene Alias:
921-S; complexin 1; complexin I; Complexin-1; Cplx1; CPX I; CPX1; CPX-I; synaphin 2; synaphin-2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10815

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
O14810

Gene Symbols:
Cplx1

Immunogen:
Recombinant protein Complexin 1. The antigen corresponds to amino acid range 1-134 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5119050

--


Antigen:
CNTN4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CNTN4

Gene Alias:
9630050B05; Axcam; axonal-associated cell adhesion molecule; Big-2; brain-derived immunoglobulin superfamily molecule; brain-derived immunoglobulin superfamily protein 2; CNTN4; CNTN4A; contactin 4; contactin-4; Kiaa3024; MGC33615; neural cell adhesion protein BIG-2; SCA16

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
152330

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q8IWV2

Gene Symbols:
CNTN4

Immunogen:
Recombinant protein Contactin 4. The antigen corresponds to amino acid range 731-980 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5119052

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Antigen:
CBF beta

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CBFB

Gene Alias:
AI893578; CBFB; CBF-beta; core binding factor beta; core-binding factor subunit beta; core-binding factor, beta subunit; PEA2; PEA2-beta; Pebp2; PEBP2B; PEBP2-beta; Pebpb2; polyomavirus enhancer binding protein 2, beta subunit; polyomavirus enhancer-binding protein 2 beta subunit; SL3/AKV core-binding factor beta subunit; SL3-3 enhancer factor 1 beta subunit; SL3-3 enhancer factor 1 subunit beta

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12400

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.9 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q08024

Gene Symbols:
CBFB

Immunogen:
Recombinant protein Core Binding Factor Beta Subunit. The antigen corresponds to amino acid range 1-187 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG