PIPA5119059

CDK4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5119059-Each-of-1 In Stock ₹ 40,769.34

PIPA5119059 - Each of 1

₹ 40,769.34

In Stock

Quantity

1

Base Price: ₹ 40,769.34

GST (18%): ₹ 7,338.481

Total Price: ₹ 48,107.821

Antigen

CDK4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Cdk4

Gene Alias

Cdk4; Cell division protein kinase 4; CMM3; Crk3; cyclin dependent kinase 4; cyclin-dependent kinase 4; MGC14458; p34<PSK-J3>/cdk4; PSK-J3; serine/threonine kinase; Unknown (protein for MGC:133903)

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1019

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.

P11802

Gene Symbols

Cdk4

Immunogen

Recombinant protein Cyclin Dependent Kinase 4. The antigen corresponds to amino acid range 6-295 of the target protein.

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • CDK4/cyclin D3 serine/threonine kinase is dimeric protein complex
  • CDK4 is a member of the cyclin-dependent protein kinase family and is involved in the control of cell proliferation during the G1 phase of cell cycle
  • CDK4 forms a complex with the D-type cyclins and is inhibited by p16 (cyclin-dependent kinase inhibitor-2)
  • CDK4 can mediate phosphorylation of the C-terminal region of Rb protein leading to an active transcriptional repression of E2F complex
  • CDC37 and HSP90 can preferentially associate with the fraction of CDK4 not bound to D-type cyclins
  • SMAD3 is a major physiologic substrate of the G1 cyclin-dependent kinases CDK4 and CDK2
  • Although CDK6 and CDK4 can both phosphorylate multiple residues in the Rb protein, they do so with different residue selectivity in vitro; CDK6 phosphorylates Thr821 while CDK4 phosphorylates Thr826 on Rb protein.

Compare Similar Items

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Img

Thermo Scientific

PIPA5119059

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Antigen:
CDK4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cdk4

Gene Alias:
Cdk4; Cell division protein kinase 4; CMM3; Crk3; cyclin dependent kinase 4; cyclin-dependent kinase 4; MGC14458; p34<PSK-J3>/cdk4; PSK-J3; serine/threonine kinase; Unknown (protein for MGC:133903)

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1019

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P11802

Gene Symbols:
Cdk4

Immunogen:
Recombinant protein Cyclin Dependent Kinase 4. The antigen corresponds to amino acid range 6-295 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5119060

--


Antigen:
COX2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PTGS2

Gene Alias:
COII; COX2; Cox-2; COXII; cyclooxygenase; cyclooxygenase 2; cyclooxygenase 2b; cyclooxygenase-2; Cytochrome c oxidase polypeptide II; Cytochrome c oxidase subunit 2; cytochrome c oxidase subunit II; glucocorticoid-regulated inflammatory cyclooxygenase; Gripghs; hCox-2; Macrophage activation-associated marker protein P71/73; mitochondrially encoded cytochrome c oxidase II; MTCO2; MT-CO2; PES-2; PGG/HS; PGH synthase 2; Pghs2; PGHS-2; Pghs-b; PHS II; PHS-2; prostaglandin G/H synthase 2; Prostaglandin H2 synthase 2; prostaglandin-endoperoxide synthase 2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase); Ptgs2; Tis10; TIS10 protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5743

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P35354

Gene Symbols:
PTGS2

Immunogen:
Recombinant protein Cyclooxygenase-2. The antigen corresponds to amino acid range 187-425 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5119062

--


Antigen:
Cyclophilin 40

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PPID

Gene Alias:
40 kDa peptidyl-prolyl cis-trans isomerase; 40 kDa peptidyl-prolyl cis-trans isomerase D; 4930564J03Rik; cyclophilin 40; cyclophilin D; cyclophilin-40; Cyclophilin-related protein; Cyp 40; Cyp D; CYP40; CYP-40; CYPD; CYP-S1; cytoplasmic cyclophilin D; EC 5.2.1.8; I79_011990; MGC33096; peptidyl-prolyl cis-trans isomerase D; peptidylprolyl isomerase D; peptidylprolyl isomerase D (cyclophilin D); PPIase; PPIase D; PPID; Ppidl; Ppif; rotamase; Rotamase D; S-cyclophilin; SCYLP; testicular tissue protein Li 147

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
361967

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q6DGG0

Gene Symbols:
PPID

Immunogen:
Recombinant protein Cyclophilin 40. The antigen corresponds to amino acid range 7-191 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5119065

--


Antigen:
CDO1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cdo1

Gene Alias:
1300002L19Rik; Cdo; CDO1; CDOI; CDO-I; cysteine dioxygenase 1, cytosolic; cysteine dioxygenase type 1; Cysteine dioxygenase type I; cysteine dioxygenase, type I; cytosolic cysteine dioxygenase 1; D18Ucla3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1036

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
0.99 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q16878

Gene Symbols:
Cdo1

Immunogen:
Recombinant protein Cysteine Dioxygenase I. The antigen corresponds to amino acid range 1-200 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG