PIPA511943

SMURF1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA511943-Each-of-1 In Stock ₹ 46,929.66

PIPA511943 - Each of 1

₹ 46,929.66

In Stock

Quantity

1

Base Price: ₹ 46,929.66

GST (18%): ₹ 8,447.339

Total Price: ₹ 55,376.999

Antigen

SMURF1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Smurf1

Gene Alias

4930431E10Rik; E3 ubiquitin ligase SMURF1; E3 ubiquitin ligase SMURF2; E3 ubiquitin-protein ligase SMURF1; E3 ubiquitin-protein ligase SMURF2; HECT-type E3 ubiquitin transferase SMURF1; HECT-type E3 ubiquitin transferase SMURF2; hSMURF1; hSMURF2; KIAA1625; mKIAA1625; RGD1309707; SMAD specific E3 ubiquitin protein ligase 1; SMAD specific E3 ubiquitin protein ligase 2; Smad ubiquitination regulatory factor 1; SMAD ubiquitination regulatory factor 2; Smad-specific E3 ubiquitin ligase 1; SMAD-specific E3 ubiquitin-protein ligase 1; SMAD-specific E3 ubiquitin-protein ligase 2; SMURF1; SMURF2

Host Species

Rabbit

Purification Method

Ammonium sulfate precipitation, Size-exclusion - Dialysis

Regulatory Status

RUO

Gene ID (Entrez)

57154, 75788

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

Q9CUN6, Q9HCE7

Gene Symbols

Smurf1

Immunogen

KLH conjugated synthetic peptide between 66-96 amino acids from the N-terminal region of human SMURF1

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is predicted to react with Xenopus and zebrafish based on sequence homology
  • Members of the transforming growth factor-beta (TGFB) family signal through type I and type II serine/threonine-kinase receptors, which in turn activate the SMAD signaling pathway
  • Bone morphogenetic protein (BMP) receptors target SMAD1, SMAD5, and SMAD8, whereas receptors for activin and TGFB (e
  • g., ACVR1 and TGFBR1, respectively) target SMAD2 and SMAD3
  • Phosphorylation of these receptor-regulated SMADs induces their association with the common-partner SMAD, SMAD4
  • Smurf1, a HECT domain E3 ubiquitin ligase, regulates cell polarity and protrusive activity and is required to maintain the transformed morphology and motility of a tumor cell
  • Atypical protein kinase C-zeta (PKC2), an effector of the Cdc42/Rac1-PAR6 polarity complex, recruits Smurf1 to cellular protrusions, where it controlled the local level of RhoA
  • Smurf1 thus links the polarity complex to degradation of RhoA in lamellipodia and filopodia to prevent RhoA signaling during dynamic membrane movements.

Compare Similar Items

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Img

Thermo Scientific

PIPA511943

--


Antigen:
SMURF1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Smurf1

Gene Alias:
4930431E10Rik; E3 ubiquitin ligase SMURF1; E3 ubiquitin ligase SMURF2; E3 ubiquitin-protein ligase SMURF1; E3 ubiquitin-protein ligase SMURF2; HECT-type E3 ubiquitin transferase SMURF1; HECT-type E3 ubiquitin transferase SMURF2; hSMURF1; hSMURF2; KIAA1625; mKIAA1625; RGD1309707; SMAD specific E3 ubiquitin protein ligase 1; SMAD specific E3 ubiquitin protein ligase 2; Smad ubiquitination regulatory factor 1; SMAD ubiquitination regulatory factor 2; Smad-specific E3 ubiquitin ligase 1; SMAD-specific E3 ubiquitin-protein ligase 1; SMAD-specific E3 ubiquitin-protein ligase 2; SMURF1; SMURF2

Host Species:
Rabbit

Purification Method:
Ammonium sulfate precipitation, Size-exclusion - Dialysis

Regulatory Status:
RUO

Gene ID (Entrez):
57154, 75788

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q9CUN6, Q9HCE7

Gene Symbols:
Smurf1

Immunogen:
KLH conjugated synthetic peptide between 66-96 amino acids from the N-terminal region of human SMURF1

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5119430

--


Antigen:
Sp17

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SPA17

Gene Alias:
band 34; cancer/testis antigen 22; CT22; SP17; SP17 protein; SP17-1; SPA17; Sperm autoantigenic protein 17; sperm protein 17; Sperm surface protein Sp17; Unknown (protein for MGC:127855); zgc:153721

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20686

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q62252

Gene Symbols:
SPA17

Immunogen:
Recombinant protein Sperm Protein 17. The antigen corresponds to amino acid range 1-149 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5119431

--


Antigen:
Sp17

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SPA17

Gene Alias:
band 34; cancer/testis antigen 22; CT22; SP17; SP17 protein; SP17-1; SPA17; Sperm autoantigenic protein 17; sperm protein 17; Sperm surface protein Sp17; Unknown (protein for MGC:127855); zgc:153721

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
85244

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
0

Gene Symbols:
SPA17

Immunogen:
Recombinant protein Sperm Protein 17

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5119435

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Antigen:
STIP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
STIP1

Gene Alias:
epididymis secretory sperm binding protein Li 94n; HEL-S-94n; HOP; hsc70/Hsp90-organizing protein; Hsp70/Hsp90 organizing protein; Hsp70/Hsp90-organizing protein; IEF SSP 3521; IEF-SSP-3521; mSTI1; NY-REN-11 antigen; P60; Renal carcinoma antigen NY-REN-11; STI1; STI1L; Stip1; stress induced phosphoprotein 1; stress-induced phosphoprotein 1; stress-induced-phosphoprotein 1; stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein); stress-inducible protein; transformation-sensitive protein IEF SSP 3521

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10963

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.62 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P31948

Gene Symbols:
STIP1

Immunogen:
Recombinant protein Stress Induced Phosphoprotein 1. The antigen corresponds to amino acid range 1-169 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG