PIPA511872

LYVE1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA511872-Each-of-1 In Stock ₹ 46,929.66

PIPA511872 - Each of 1

₹ 46,929.66

In Stock

Quantity

1

Base Price: ₹ 46,929.66

GST (18%): ₹ 8,447.339

Total Price: ₹ 55,376.999

Antigen

LYVE1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Lyve1

Gene Alias

1200012G08Rik; cell surface retention sequence binding protein-1; cell surface retention sequence-binding protein 1; CRSBP1; CRSBP-1; extra cellular link domain-containing 1; extracellular link domain containing 1; extracellular link domain-containing 1; extracellular link domain-containing protein 1; HAR; hyaluronic acid receptor; lymphatic endothelial hyaluronan receptor LYVE-1; lymphatic vessel endothelial HA receptor-1; lymphatic vessel endothelial HA recptor-1; lymphatic vessel endothelial hyaluronan receptor 1; lymphatic vessel endothelial hyaluronic acid receptor 1; LYVE1; LYVE-1; sLyve 1; sLyve1; soluble LYVE 1; soluble LYVE1; UNQ230/PRO263; XLKD1

Host Species

Rabbit

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

10894, 114332

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

2 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

Q8BHC0, Q9Y5Y7

Gene Symbols

Lyve1

Immunogen

KLH conjugated synthetic peptide between 46-77 amino acids from the N-terminal region of human XLKD1

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • LYVE1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall
  • The deduced amino acid sequence of LYVE1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module, the prototypic HA binding domain of the Link protein superfamily
  • Like CD44, the LYVE1 molecule binds both soluble and immobilized HA
  • However, unlike CD44, the LYVE1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels
  • Hence, LYVE1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves
  • LYVE1 is a type I integral membrane glycoprotein
  • LYVE-1 is expressed primarily on lymphatic vessel endothelium and is likely to be involved in regulating the traffic of leucocytes and tumor cells to lymph nodes
  • The lymphatic vasculature forms a second circulatory system that drains extracellular fluid from the tissues and provides an exclusive environment in which immune cells can encounter and respond to foreign antigen
  • A number of molecules have been identified as markers for lymphatic endothelium which include LYVE1, PALE, VEGFR3, and podoplanin
  • Diseases associated with LYVE1 dysfunction includes Complete Androgen Insensitivity Syndrome.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA511872

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Antigen:
LYVE1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Lyve1

Gene Alias:
1200012G08Rik; cell surface retention sequence binding protein-1; cell surface retention sequence-binding protein 1; CRSBP1; CRSBP-1; extra cellular link domain-containing 1; extracellular link domain containing 1; extracellular link domain-containing 1; extracellular link domain-containing protein 1; HAR; hyaluronic acid receptor; lymphatic endothelial hyaluronan receptor LYVE-1; lymphatic vessel endothelial HA receptor-1; lymphatic vessel endothelial HA recptor-1; lymphatic vessel endothelial hyaluronan receptor 1; lymphatic vessel endothelial hyaluronic acid receptor 1; LYVE1; LYVE-1; sLyve 1; sLyve1; soluble LYVE 1; soluble LYVE1; UNQ230/PRO263; XLKD1

Host Species:
Rabbit

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
10894, 114332

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
2 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q8BHC0, Q9Y5Y7

Gene Symbols:
Lyve1

Immunogen:
KLH conjugated synthetic peptide between 46-77 amino acids from the N-terminal region of human XLKD1

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5118723

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Antigen:
Phospho-TSC2 (Ser981)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TSC2

Gene Alias:
LAM; Nafld; OTTHUMP00000198394; PPP1R160; protein phosphatase 1, regulatory subunit 160; Rc; renal carcinoma; Tcs2; Tsc2; TSC4; Tuberin; tuberous sclerosis 2; tuberous sclerosis 2 homolog protein; tuberous sclerosis 2 protein; Tuberous sclerosis 2 protein homolog

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22084, 24855, 7249

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P49815, P49816, Q61037

Gene Symbols:
TSC2

Immunogen:
A synthesized peptide derived from human TSC2(Accession P49815), corresponding to amino acid residues around phosphorylated Ser981.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5118726

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Antigen:
Phospho-Cyclin E (Ser399)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CCNE1

Gene Alias:
AW538188; Ccne; Ccne1; CycE1; CYCLE; cyclin E; cyclin E1; cyclin Es; cyclin Et; E-S; G1/S-specific cyclin-E1; pCCNE1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12447, 25729, 898

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P24864, P39949, Q61457

Gene Symbols:
CCNE1

Immunogen:
A synthesized peptide derived from human CCNE1(Accession P24864), corresponding to amino acid residues around phosphorylated Ser399.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5118729

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Antigen:
Phospho-PRK1/PRK2 (Thr774, Thr816)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PKN2

Gene Alias:
6030436C20Rik; AI507382; cardiolipin-activated protein kinase Pak2; DBK; F730027O18Rik; p140 kinase; PAK1; PAK-1; PAK2; Pak-2; Pkn; PKN gamma; Pkn1; Pkn2; PKN-ALPHA; Prk1; Prk2; Prkcl1; PRKCL2; PRO2042; protease-activated kinase 1; protease-activated kinase 2; protein kinase C-like 1; Protein kinase C-like 2; protein kinase C-like PKN; protein kinase C-related kinase 1; protein kinase N1; protein kinase N2; protein kinase PKN; protein kinase PKN-alpha; Protein-kinase C-related kinase 1; protein-kinase C-related kinase 2; serine/threonine kinase 3; serine/threonine kinase 7; serine/threonine protein kinase N; serine/threonine-protein kinase N1; Serine/threonine-protein kinase N2; serine-threonine kinase N; serine-threonine protein kinase N; Stk3; Stk7

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
207122, 29355, 5585, 5586

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O08874, Q16512, Q16513, Q63433

Gene Symbols:
PKN1, PKN2

Immunogen:
A synthesized peptide derived from human PKN1(Accession Q16512), corresponding to amino acid residues around phosphorylated Thr774.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG