PIPA5119597
SARS-CoV-2 NSP1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5119597-Each-of-1 | In Stock | ₹ 43,079.46 |
PIPA5119597 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,079.46
GST (18%): ₹ 7,754.303
Total Price: ₹ 50,833.763
Antigen
SARS-CoV-2 NSP1
Classification
Polyclonal
Conjugate
Unconjugated
Gene Alias
COVID19 Nsp1; COVID-19 Nsp1; SARS-CoV-2 Nonstructural Protein 1; SARS-CoV2 NSP1; SARS-COV-2 NSP1
Immunogen
Recombinant protein encompassing a sequence within the center region of SARS-CoV-2 (COVID-19) nsp1 (SARS-CoV-2 (strain Wuhan-Hu-1). The exact sequence is proprietary.
Quantity
100 μL
Primary or Secondary
Primary
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Target Species
Virus
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Store as concentrated solution
- Centrifuge briefly prior to opening vial
- For short-term storage (1-2 weeks), store at 4°C
- For long-term storage, aliquot and store at -20°C or below
- Avoid multiple freeze-thaw cycles
- Inhibits host translation by interacting with the 40S ribosomal subunit (PubMed:32680882)
- Nsp1 C terminus binds to and obstructs ribosomal mRNA entry tunnel (PubMed:32680882)
- Thereby inhibits antiviral response triggered by innate immunity or interferons (PubMed:32680882)
- The nsp1-40S ribosome complex further induces an endonucleolytic cleavage near the 5'UTR of host mRNAs, targeting them for degradation
- Viral mRNAs are not susceptible to nsp1-mediated endonucleolytic RNA cleavage thanks to the presence of a 5'-end leader sequence and are therefore protected from degradation
- By suppressing host gene expression, nsp1 facilitates efficient viral gene expression in infected cells and evasion from host immune response.
Compare Similar Items
Show Difference
Antigen: SARS-CoV-2 NSP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene Alias: COVID19 Nsp1; COVID-19 Nsp1; SARS-CoV-2 Nonstructural Protein 1; SARS-CoV2 NSP1; SARS-COV-2 NSP1
Immunogen: Recombinant protein encompassing a sequence within the center region of SARS-CoV-2 (COVID-19) nsp1 (SARS-CoV-2 (strain Wuhan-Hu-1). The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Target Species: Virus
Product Type: Antibody
Isotype: IgG
Antigen:
SARS-CoV-2 NSP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene Alias:
COVID19 Nsp1; COVID-19 Nsp1; SARS-CoV-2 Nonstructural Protein 1; SARS-CoV2 NSP1; SARS-COV-2 NSP1
Immunogen:
Recombinant protein encompassing a sequence within the center region of SARS-CoV-2 (COVID-19) nsp1 (SARS-CoV-2 (strain Wuhan-Hu-1). The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Target Species:
Virus
Product Type:
Antibody
Isotype:
IgG
Antigen: SARS-CoV-2 NSP12
Classification: Polyclonal
Conjugate: Unconjugated
Gene Alias: COVID19 Nsp12; COVID-19 Nsp12; SARS-CoV-2 Nonstructural Protein 12; SARS-CoV2 NSP12; SARS-COV-2 NSP12
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of SARS-CoV-2 (COVID-19) nsp12 (Strain:Wuhan-Hu-1). The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.33 mg/mL
Formulation: PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Target Species: Virus
Product Type: Antibody
Isotype: IgG
Antigen:
SARS-CoV-2 NSP12
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene Alias:
COVID19 Nsp12; COVID-19 Nsp12; SARS-CoV-2 Nonstructural Protein 12; SARS-CoV2 NSP12; SARS-COV-2 NSP12
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of SARS-CoV-2 (COVID-19) nsp12 (Strain:Wuhan-Hu-1). The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.33 mg/mL
Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Target Species:
Virus
Product Type:
Antibody
Isotype:
IgG
Antigen: SARS-CoV-2 NSP12
Classification: Polyclonal
Conjugate: Unconjugated
Gene Alias: COVID19 Nsp12; COVID-19 Nsp12; SARS-CoV-2 Nonstructural Protein 12; SARS-CoV2 NSP12; SARS-COV-2 NSP12
Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of SARS-CoV-2 (COVID-19) nsp12 (Strain:Wuhan-Hu-1). The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Target Species: Virus
Product Type: Antibody
Isotype: IgG
Antigen:
SARS-CoV-2 NSP12
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene Alias:
COVID19 Nsp12; COVID-19 Nsp12; SARS-CoV-2 Nonstructural Protein 12; SARS-CoV2 NSP12; SARS-COV-2 NSP12
Immunogen:
Recombinant protein encompassing a sequence within the N-terminus region of SARS-CoV-2 (COVID-19) nsp12 (Strain:Wuhan-Hu-1). The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Target Species:
Virus
Product Type:
Antibody
Isotype:
IgG
Antigen: SARS/SARS-CoV-2 Nucleocapsid
Classification: Polyclonal
Conjugate: Unconjugated
Gene Alias: COVID19 Nucleocapsid, COVID-19 nucleocapsid, COVID19 Spike nucleocapsid, SARS-CoV-2 N
Immunogen: Full length SARS-CoV-2 (COVID-19) nucleocapsid Recombinant protein. (SARS-CoV-2 (strain Wuhan-Hu-1)
Quantity: 100 μL
Primary or Secondary: Primary
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 0.33 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Target Species: Virus
Product Type: Antibody
Isotype: IgG
Antigen:
SARS/SARS-CoV-2 Nucleocapsid
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene Alias:
COVID19 Nucleocapsid, COVID-19 nucleocapsid, COVID19 Spike nucleocapsid, SARS-CoV-2 N
Immunogen:
Full length SARS-CoV-2 (COVID-19) nucleocapsid Recombinant protein. (SARS-CoV-2 (strain Wuhan-Hu-1)
Quantity:
100 μL
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
0.33 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Target Species:
Virus
Product Type:
Antibody
Isotype:
IgG