PIPA5119617
TMEM119 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5119617-Each-of-1 | In Stock | ₹ 43,079.46 |
PIPA5119617 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,079.46
GST (18%): ₹ 7,754.303
Total Price: ₹ 50,833.763
Antigen
TMEM119
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TMEM119
Gene Alias
AW208946; BC025600; OBIF; Osteoblast induction factor; PSEC0199; Tmem119; Transmembrane protein 119; UNQ731/PRO1415
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
231633
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Concentration
1 mg/mL
Formulation
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.
Q8R138
Gene Symbols
TMEM119
Immunogen
Recombinant protein encompassing a sequence within the center region of mouse TMEM119. The exact sequence is proprietary.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Store as concentrated solution
- Centrifuge briefly prior to opening vial
- For short-term storage (1-2 weeks), store at 4°C
- For long-term storage, aliquot and store at -20°C or below
- Avoid multiple freeze-thaw cycles
- Tmem119 encodes a single-pass type I transmembrane protein which seems to interact with a multitude of micro-RNAs as well as certain transcription factors such as SMAD1, SMAD5 and RUNX2
- Tmem119 has been identified as a surface marker of microglia that can be used to reliably distinguish microglia from infiltrating macrophages
- Microglial cells are phagocytes that are restricted to the brain and involved in clearing up debris and dendrite pruning of neurons
- They display a high functional plasticity, balancing neuroprotective and neurotoxic functions, which is reflected by their distinct physiology in response to changes in their microenvironment
- Microglia are particularly mobile in areas of the brain undergoing restructuring
- Reactive microglia co-express the marker Iba1
- In a pathological context, microglia have been associated with differentiation of pathogenic/inflammatory A1 type astrocytes by secretion of Cq1, IL-1a and TNF when stimulated with LPS, and thought to contribute to the pathology of several neurodegenerative diseases such as Alzheimers, Parkinsons, Chorea Huntingtons disease and Multiple Sclerosis
- The specific function Tmem119 plays on microglial cells remains unclear
- Outside of the neural system, Tmem119 seems to be involved in osteoblast differentiation/ossification.
Compare Similar Items
Show Difference
Antigen: TMEM119
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TMEM119
Gene Alias: AW208946; BC025600; OBIF; Osteoblast induction factor; PSEC0199; Tmem119; Transmembrane protein 119; UNQ731/PRO1415
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 231633
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: Q8R138
Gene Symbols: TMEM119
Immunogen: Recombinant protein encompassing a sequence within the center region of mouse TMEM119. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
TMEM119
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TMEM119
Gene Alias:
AW208946; BC025600; OBIF; Osteoblast induction factor; PSEC0199; Tmem119; Transmembrane protein 119; UNQ731/PRO1415
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
231633
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.:
Q8R138
Gene Symbols:
TMEM119
Immunogen:
Recombinant protein encompassing a sequence within the center region of mouse TMEM119. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: TOMM7
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TOMM7
Gene Alias: 1110020J08Rik; 6.2 kd protein; AD-014; AW047273; mitochondrial import receptor subunit TOM7 homolog; TOM7; TOMM07; TOMM7; Translocase of outer membrane 7 kDa subunit homolog; translocase of outer mitochondrial membrane 7; translocase of outer mitochondrial membrane 7 homolog; translocase of outer mitochondrial membrane 7 homolog (yeast)
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 54543
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q9P0U1
Gene Symbols: TOMM7
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human TOMM7.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TOMM7
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TOMM7
Gene Alias:
1110020J08Rik; 6.2 kd protein; AD-014; AW047273; mitochondrial import receptor subunit TOM7 homolog; TOM7; TOMM07; TOMM7; Translocase of outer membrane 7 kDa subunit homolog; translocase of outer mitochondrial membrane 7; translocase of outer mitochondrial membrane 7 homolog; translocase of outer mitochondrial membrane 7 homolog (yeast)
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
54543
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q9P0U1
Gene Symbols:
TOMM7
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human TOMM7.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: USP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: USP1
Gene Alias: Deubiquitinating enzyme 1; EMBL:AAH92574.1, ECO:0000312; hUBP; MGC137005 protein; RGD:1306461}; ubiquitin carboxyl terminal hydrolase 1; ubiquitin carboxyl-terminal hydrolase 1; ubiquitin carboxyl-terminal hydrolase 1-like protein; ubiquitin specific peptidase 1; ubiquitin specific processing protease 1; ubiquitin specific protease 1; ubiquitin thioesterase 1; ubiquitin thiolesterase 1; ubiquitin-specific-processing protease 1; UBP; usp1; usp1 {ECO:0000312
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7398
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 2.77 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: O94782
Gene Symbols: USP1
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human USP1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
USP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
USP1
Gene Alias:
Deubiquitinating enzyme 1; EMBL:AAH92574.1, ECO:0000312; hUBP; MGC137005 protein; RGD:1306461}; ubiquitin carboxyl terminal hydrolase 1; ubiquitin carboxyl-terminal hydrolase 1; ubiquitin carboxyl-terminal hydrolase 1-like protein; ubiquitin specific peptidase 1; ubiquitin specific processing protease 1; ubiquitin specific protease 1; ubiquitin thioesterase 1; ubiquitin thiolesterase 1; ubiquitin-specific-processing protease 1; UBP; usp1; usp1 {ECO:0000312
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7398
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
2.77 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.:
O94782
Gene Symbols:
USP1
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human USP1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: VGLUT2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SLC17A6
Gene Alias: 2900073D12Rik; differentation-associated Na-dependent inorganic phosphate cotransporter; differentiation-associated BNPI; Differentiation-associated Na(+)-dependent inorganic phosphate cotransporter; differentiation-associated Na-dependent inorganic phosphate cotransporter; Dnpi; SLC17A6; solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6; solute carrier family 17 (vesicular glutamate transporter), member 6; solute carrier family 17 member 6; Vesicular glutamate transporter 2; VGlU2; VGLUT2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 140919, 84487
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.22 mg/mL
Formulation: PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: Q8BLE7, Q9JI12
Gene Symbols: SLC17A6
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of mouse VGLUT2.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
VGLUT2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SLC17A6
Gene Alias:
2900073D12Rik; differentation-associated Na-dependent inorganic phosphate cotransporter; differentiation-associated BNPI; Differentiation-associated Na(+)-dependent inorganic phosphate cotransporter; differentiation-associated Na-dependent inorganic phosphate cotransporter; Dnpi; SLC17A6; solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6; solute carrier family 17 (vesicular glutamate transporter), member 6; solute carrier family 17 member 6; Vesicular glutamate transporter 2; VGlU2; VGLUT2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
140919, 84487
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.22 mg/mL
Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.:
Q8BLE7, Q9JI12
Gene Symbols:
SLC17A6
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of mouse VGLUT2.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Product Type:
Antibody
Isotype:
IgG