PIPA5119902
TMEM119 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5119902-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5119902 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
TMEM119
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TMEM119
Gene Alias
AW208946; BC025600; OBIF; Osteoblast induction factor; PSEC0199; Tmem119; Transmembrane protein 119; UNQ731/PRO1415
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
231633, 338773
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
Q4V9L6, Q8R138
Gene Symbols
TMEM119
Immunogen
Synthetic peptide within human TMEM119 aa 11-52/283
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Control: Mouse brain tissue lysate, mouse cerebellum tissue lysate, SH-SY5Y
- Subcellular Location: Endoplasmic reticulum membrane, Cell membrane, Cytoplasm
- Tmem119 encodes a single-pass type I transmembrane protein which seems to interact with a multitude of micro-RNAs as well as certain transcription factors such as SMAD1, SMAD5 and RUNX2
- Tmem119 has been identified as a surface marker of microglia that can be used to reliably distinguish microglia from infiltrating macrophages
- Microglial cells are phagocytes that are restricted to the brain and involved in clearing up debris and dendrite pruning of neurons
- They display a high functional plasticity, balancing neuroprotective and neurotoxic functions, which is reflected by their distinct physiology in response to changes in their microenvironment
- Microglia are particularly mobile in areas of the brain undergoing restructuring
- Reactive microglia co-express the marker Iba1
- In a pathological context, microglia have been associated with differentiation of pathogenic/inflammatory A1 type astrocytes by secretion of Cq1, IL-1a and TNF when stimulated with LPS, and thought to contribute to the pathology of several neurodegenerative diseases such as Alzheimers, Parkinsons, Chorea Huntingtons disease and Multiple Sclerosis
- The specific function Tmem119 plays on microglial cells remains unclear
- Outside of the neural system, Tmem119 seems to be involved in osteoblast differentiation/ossification.
Compare Similar Items
Show Difference
Antigen: TMEM119
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TMEM119
Gene Alias: AW208946; BC025600; OBIF; Osteoblast induction factor; PSEC0199; Tmem119; Transmembrane protein 119; UNQ731/PRO1415
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 231633, 338773
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: Q4V9L6, Q8R138
Gene Symbols: TMEM119
Immunogen: Synthetic peptide within human TMEM119 aa 11-52/283
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
TMEM119
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TMEM119
Gene Alias:
AW208946; BC025600; OBIF; Osteoblast induction factor; PSEC0199; Tmem119; Transmembrane protein 119; UNQ731/PRO1415
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
231633, 338773
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
Q4V9L6, Q8R138
Gene Symbols:
TMEM119
Immunogen:
Synthetic peptide within human TMEM119 aa 11-52/283
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: FARS2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: FARS2
Gene Alias: COXPD14; dJ236A3.1 (phenylalanine-tRNA synthetase); dJ520B18.2; dJ520B18.2 (FARS1 (phenylalanine-tRNA synthetase)); Fars1; FARS2; HSPC320; mitochondrial PHERS; pheny; phenylalanine translase; phenylalanine tRNA ligase 2, mitochondrial; phenylalanine--tRNA ligase, mitochondrial; phenylalanine-tRNA synthetase 1 (mitochondrial); phenylalanine-tRNA synthetase 2 (mitochondrial); Phenylalanyl-tRNA synthetase; phenylalanyl-tRNA synthetase 2, mitochondrial; phenylalanyl-tRNA synthetase, mitochondrial; phenylalanyl-tRNA synthetase, mitochondrial; phenylalanine--tRNA ligase, mitochondrial; pheRS
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10667, 306879, 69955
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: O95363, Q6AYQ3, Q99M01
Gene Symbols: FARS2
Immunogen: Synthetic peptide within human FARS2 aa 50-100/451
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
FARS2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
FARS2
Gene Alias:
COXPD14; dJ236A3.1 (phenylalanine-tRNA synthetase); dJ520B18.2; dJ520B18.2 (FARS1 (phenylalanine-tRNA synthetase)); Fars1; FARS2; HSPC320; mitochondrial PHERS; pheny; phenylalanine translase; phenylalanine tRNA ligase 2, mitochondrial; phenylalanine--tRNA ligase, mitochondrial; phenylalanine-tRNA synthetase 1 (mitochondrial); phenylalanine-tRNA synthetase 2 (mitochondrial); Phenylalanyl-tRNA synthetase; phenylalanyl-tRNA synthetase 2, mitochondrial; phenylalanyl-tRNA synthetase, mitochondrial; phenylalanyl-tRNA synthetase, mitochondrial; phenylalanine--tRNA ligase, mitochondrial; pheRS
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10667, 306879, 69955
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
O95363, Q6AYQ3, Q99M01
Gene Symbols:
FARS2
Immunogen:
Synthetic peptide within human FARS2 aa 50-100/451
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PDE6A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PDE6A
Gene Alias: cGMP phosphodiesterase alpha; cGMP phosphodiesterase alpha subunit; cGMP phosphodiesterase alpha subunit (EC 3.1.4.35); CGPR-A; cyclic GMP phosphodiesterase alpha subunit; GMP phosphodiesterase alpha subunit; GMP-PDE alpha; nmf282; PDE V-B1; PDE6A; PDEA; phosphodiesterase 6A; phosphodiesterase 6A, cGMP-specific, rod, alpha; phosphodiesterase, cyclic GMP (rod receptor), alpha polypeptide; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha; rod photoreceptor cGMP phosphodiesterase alpha subunit; RP43; unnamed protein product
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 225600, 307401, 5145
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P16499, P27664
Gene Symbols: PDE6A
Immunogen: Recombinant protein within human PDE6 alpha aa 201-400
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PDE6A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PDE6A
Gene Alias:
cGMP phosphodiesterase alpha; cGMP phosphodiesterase alpha subunit; cGMP phosphodiesterase alpha subunit (EC 3.1.4.35); CGPR-A; cyclic GMP phosphodiesterase alpha subunit; GMP phosphodiesterase alpha subunit; GMP-PDE alpha; nmf282; PDE V-B1; PDE6A; PDEA; phosphodiesterase 6A; phosphodiesterase 6A, cGMP-specific, rod, alpha; phosphodiesterase, cyclic GMP (rod receptor), alpha polypeptide; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha; rod photoreceptor cGMP phosphodiesterase alpha subunit; RP43; unnamed protein product
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
225600, 307401, 5145
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P16499, P27664
Gene Symbols:
PDE6A
Immunogen:
Recombinant protein within human PDE6 alpha aa 201-400
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: TIFY11A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: LOC4331832
Gene Alias: Jasmonate ZIM domain-containing protein 9
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 4331832
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: 0
Gene Symbols: LOC4331832
Immunogen: Recombinant protein within rice TIFY11A aa 50-179/179
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Plant
Product Type: Antibody
Isotype: IgG
Antigen:
TIFY11A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
LOC4331832
Gene Alias:
Jasmonate ZIM domain-containing protein 9
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
4331832
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
0
Gene Symbols:
LOC4331832
Immunogen:
Recombinant protein within rice TIFY11A aa 50-179/179
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Plant
Product Type:
Antibody
Isotype:
IgG