PIPA5120251

ARC Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5120251-Each-of-1 In Stock ₹ 43,079.46

PIPA5120251 - Each of 1

₹ 43,079.46

In Stock

Quantity

1

Base Price: ₹ 43,079.46

GST (18%): ₹ 7,754.303

Total Price: ₹ 50,833.763

Antigen

ARC

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NOL3

Gene Alias

activity regulated cytoskeletal-associated protein; activity regulated cytoskeleton associated protein; activity-regulated cytoskeleton-associated protein; Activity-regulated gene 3.1 protein; activity-regulated gene 3.1 protein homolog; Apoptosis repressor with CARD; ARC; arc {ECO:0000312; ARC/ARG3.1; Arc3.1; Arg3.1; B430311C09Rik; C86064; FCM; hArc; KIAA0278; mArc; Muscle-enriched cytoplasmic protein; MYC; MYP; Nol3; NOP; Nop 30; Nop30; Nucleolar protein 3; nucleolar protein 3 (apoptosis repressor with CARD domain); nucleolar protein of 30 kDa; rg3.1; RGD:62037}

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

78688, 8996

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

0.48 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

O60936, Q9D1X0

Gene Symbols

NOL3

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-208 of human NOL3 (NP_003937.1).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Positive test controls include: SW620, Mouse heart
  • The target is usually found in the following locations: Cytoplasm, Lipid-anchor, Membrane, Mitochondrion, Nucleus, Sarcoplasmic reticulum, nucleolus
  • Immunogen sequence: MGNAQERPSE TIDRERKRLV ETLQADSGLL LDALLARGVL TGPEYEALDA LPDAERRVRR LLLLVQGKGE AACQELLRCA QRTAGAPDPA WDWQHVGPGY RDRSYDPPCP GHWTPEAPGS GTTCPGLPRA SDPDEAGGPE GSEAVQSGTP EEPEPELEAE ASKEAEPEPE PEPELEPEAE AEPEPELEPE PDPEPEPDFE ERDESEDS ARC (also known as NOL3 - Nucleolar protein 3) has two isoforms
  • Isoform 1 is involved in RNA splicing
  • Isoform 2 functions as an apoptosis repressor that blocks multiple modes of cell death
  • ARC inhibits extrinsic apoptotic pathways two different ways
  • The first is by interacting with FAS and FADD upon FAS activation blocking death-inducing signaling complex (DISC) assembly
  • The second way is by interacting with CASP8 in a mitochondria localization-and phosphorylation-dependent manner, which in turn limits the amount of soluble CASP8 avaliable for DISC-mediated activation
  • ARC also inhibits intrinsic apoptotic pathways in response to a wide range of stresses through interactions with BAX
  • This results in BAX inactivation and prevents mitochondrial dysfunction and release of pro-apoptotic factors
  • Mutations affecting the gene can results in myoclonus, familiam cortical.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5120251

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Antigen:
ARC

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NOL3

Gene Alias:
activity regulated cytoskeletal-associated protein; activity regulated cytoskeleton associated protein; activity-regulated cytoskeleton-associated protein; Activity-regulated gene 3.1 protein; activity-regulated gene 3.1 protein homolog; Apoptosis repressor with CARD; ARC; arc {ECO:0000312; ARC/ARG3.1; Arc3.1; Arg3.1; B430311C09Rik; C86064; FCM; hArc; KIAA0278; mArc; Muscle-enriched cytoplasmic protein; MYC; MYP; Nol3; NOP; Nop 30; Nop30; Nucleolar protein 3; nucleolar protein 3 (apoptosis repressor with CARD domain); nucleolar protein of 30 kDa; rg3.1; RGD:62037}

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
78688, 8996

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.48 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O60936, Q9D1X0

Gene Symbols:
NOL3

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-208 of human NOL3 (NP_003937.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5120252

--


Antigen:
IGF2BP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IGF2BP2

Gene Alias:
C330012H03Rik; Hepatocellular carcinoma autoantigen p62; IGF2 mRNA-binding protein 2; IGF2BP2; IGF-II mRNA-binding protein 2; Imp2; IMP-2; insulin like growth factor 2 mRNA binding protein 2; insulin-like growth factor 2 mRNA binding protein 2; insulin-like growth factor 2 mRNA-binding protein 2; insulin-like growth factor 2, binding protein 2; Neilsen; p62; RGD1305614; VICKZ family member 2; VICKZ2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10644, 303824, 319765

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration:
1.58 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q5SF07, Q9Y6M1

Gene Symbols:
IGF2BP2

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 500-599 of human IGF2BP2/IMP2 (NP_0065393)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5120253

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Antigen:
TMPRSS11A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TMPRSS11A

Gene Alias:
airway trypsin-like protease 1; Desc3; DESC-3; ECRG1; epidermal type II transmembrane serine protease; epidermal type-II transmembrane serine protease; Esophageal cancer-susceptibility gene 1 protein; Gm7; Hatl1; HESP; Serine protease DESC3; TMPRSS11A; Transmembrane protease serine 11A; transmembrane protease, serine 11A

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
194597, 339967, 686581

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
2.07 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q3UQ41, Q6ZMR5

Gene Symbols:
TMPRSS11A

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 300-421 of human TMPRSS11A (NP_872412.3).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5120254

--


Antigen:
MYL2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MYL2

Gene Alias:
cardiac myosin light chain 2; cardiac myosin light chain-2; cardiac ventricular myosin light chain 2; CMH10; DKFZp779C0562; hypothetical protein LOC677750; Mlc2; MLC-2; mLc2b; MLC-2s/v; MLC2V; MLC-2v; myl2; myl2b; Mylpc; myosin light chain 2; myosin light chain 2, slow skeletal/ventricular muscle isoform; myosin light chain 2V; myosin light chain phosphatase; myosin light chain, phosphorylatable, cardiac ventricles; myosin light chain-2; myosin regulatory light chain 2, ventricular/cardiac muscle isoform; myosin regulatory light chain 2b; myosin regulatory light chain ventricular isoform; myosin, light chain 2, regulatory, cardiac, slow; myosin, light chain 2b, regulatory, cardiac, slow; myosin, light polypeptide 2, regulatory, cardiac, slow; myosin, light polypeptide 2b, regulatory, cardiac, slow; regulatory light chain of myosin; RLC of myosin; slow cardiac myosin regulatory light chain 2; ventricular myosin light chain 2; ventricular myosin regulatory light chain; zgc:136848

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17906, 363925

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.87 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P08733, P51667

Gene Symbols:
MYL2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-166 of human MYL2 (NP_0004232)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG