PIPA5120637

MNK1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5120637-Each-of-1 In Stock ₹ 43,079.46

PIPA5120637 - Each of 1

₹ 43,079.46

In Stock

Quantity

1

Base Price: ₹ 43,079.46

GST (18%): ₹ 7,754.303

Total Price: ₹ 50,833.763

Antigen

MNK1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MKNK1

Gene Alias

2410048M24Rik; MAP kinase interacting serine/threonine kinase 1; MAP kinase signal-integrating kinase 1; MAP kinase-interacting serine/threonine kinase 1; MAP kinase-interacting serine/threonine-protein kinase 1; MAPK signal-integrating kinase 1; MKNK1; Mnk1; OTTHUMP00000009675; OTTHUMP00000009676

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

17346, 500526, 8569

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.81 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.

O08605, Q4G050, Q9BUB5

Gene Symbols

MKNK1

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 374-465 of human MKNK1 (NP_003675.2).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Positive test controls include: HeLa, 293T, HepG2, Mouse pancreas, Rat skeletal muscle
  • The target is usually found in the following locations: Cytoplasm, Cytoplasm, Nucleus
  • Immunogen sequence: VQGQAPEKGL PTPQVLQRNS STMDLTLFAA EAIALNRQLS QHEENELAEE PEALADGLCS MKLSPPCKSR LARRRALAQA GRGEDRSPPT AL The Map kinase-interacting kinases (MKNK1 and MKNK2) are activated by Map kinases, regulate protein synthesis by phosphroylation eIF4E on Ser209, and may contribute to tumorigenesis
  • Overexpression of Mnk2 results in increased phosphorylation of endogenous eIF-4E, showing that it can act as an eIF-4E kinase in vivo
  • Mnk2 may play a role in the response to environmental stress and cytokines
  • Expression of active mutants of MNK1 and MNK2 in 293 cells diminishes cap-dependent translation relative to cap-independent translation in a transient reporter assay
  • Human Mnk2 is homologous to murine Mnk2 (approximately 94% identical) and human Mnk1 (71% identical)
  • In vitro phosphorylation studies show that Mnk2 is a significantly better substrate than Mnk1 for extracellular signal-regulated kinase 2 (Erk2), p38MAPKalpha, and p38MAPKbeta.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA5120637

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Antigen:
MNK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MKNK1

Gene Alias:
2410048M24Rik; MAP kinase interacting serine/threonine kinase 1; MAP kinase signal-integrating kinase 1; MAP kinase-interacting serine/threonine kinase 1; MAP kinase-interacting serine/threonine-protein kinase 1; MAPK signal-integrating kinase 1; MKNK1; Mnk1; OTTHUMP00000009675; OTTHUMP00000009676

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17346, 500526, 8569

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.81 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
O08605, Q4G050, Q9BUB5

Gene Symbols:
MKNK1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 374-465 of human MKNK1 (NP_003675.2).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5120638

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Antigen:
PLD3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PLD3

Gene Alias:
5'-3' exonuclease PLD3; phospholipase D3; AD19; Choline phosphatase 3; hindIII K4L homolog; HUK4; HU-K4; phosphatidylcholine-hydrolyzing phospholipase D3; phospholipase D family member 3; phospholipase D family, member 3; phospholipase D3; PLD 3; Pld3; Sam9; Sam-9; Schwannoma-associated protein 9; Unknown (protein for MGC:126910)

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18807

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
2.2 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
O35405

Gene Symbols:
PLD3

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 279-490 of human PLD3 (NP_001026866).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA5120639

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Antigen:
PRMT8

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRMT8

Gene Alias:
arginine methyltransferase 8; heterogeneous nuclear ribonucleoprotein methyltransferase-like 4; heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4; HMT1 hnRNP methyltransferase-like 3; Hrmt1l3; HRMT1L4; PRMT8; protein arginine methyltransferase 8; protein arginine N-methyltransferase 4; protein arginine N-methyltransferase 8; protein arginine N-methyltransferase 8; protein arginine methyltransferase 8

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
381813, 56341, 688502

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
2.85 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
Q6PAK3, Q9NR22

Gene Symbols:
PRMT8

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 200-380 of human PRMT8 (NP_062828.3).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5120642

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Antigen:
IER5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IER5

Gene Alias:
Ier5; immediate early response 5; immediate early response gene 5 protein; immediately early response; MGC102760; PP4583; SBBI48; si:dz129i22.1; Unknown (protein for MGC:136422); wu:fa99a02; wu:fb04b03; wu:fb11f08; zgc:136422

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15939, 498256, 51278

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.33 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
O89113, Q5VY09

Gene Symbols:
IER5

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human IER5 (NP_057629.2).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG