PIPA5121351
Phospho-RIP1 (Ser166) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5121351-Each-of-1 | In Stock | ₹ 44,811.50 |
PIPA5121351 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,811.50
GST (18%): ₹ 8,066.07
Total Price: ₹ 52,877.57
Antigen
Phospho-RIP1 (Ser166)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
RIPK1
Gene Alias
cell death protein RIP; D330015H01Rik; FLJ39204; OTTHUMP00000015955; receptor (TNFRSF)-interacting serine-threonine kinase 1; receptor interacting serine/threonine kinase 1; receptor-interacting protein 1; receptor-interacting protein kinase 1; receptor-interacting serine/threonine-protein kinase 1; Rinp; RIP; RIP1; RIP-1; RIP1 (CT); RIPK1; serine/threonine-protein kinase RIP
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
19766, 8737
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
1.04 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.
Q13546, Q60855
Gene Symbols
RIPK1
Immunogen
A synthetic phosphorylated peptide around S166 of human RIPK1/RIP (NP_003795.2).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive test controls include: HT-29, NIH/3T3
- Immunogen sequence: MWSKL Serine-threonine kinase which transduces inflammatory and cell-death signals (programmed necrosis) following death receptors ligation, activation of pathogen recognition receptors (PRRs), and DNA damage
- Upon activation of TNFR1 by the TNF-alpha family cytokines, TRADD and TRAF2 are recruited to the receptor
- Phosphorylates DAB2IP at 'Ser-728' in a TNF-alpha-dependent manner, and thereby activates the MAP3K5-JNK apoptotic cascade
- Ubiquitination by TRAF2 via 'Lys-63'-link chains acts as a critical enhancer of communication with downstream signal transducers in the mitogen-activated protein kinase pathway and the NF-kappa-B pathway, which in turn mediate downstream events including the activation of genes encoding inflammatory molecules
- Polyubiquitinated protein binds to IKBKG/NEMO, the regulatory subunit of the IKK complex, a critical event for NF-kappa-B activation
- Interaction with other cellular RHIM-containing adapters initiates gene activation and cell death
- RIPK1 and RIPK3 association, in particular, forms a necrosis-inducing complex.
Compare Similar Items
Show Difference
Antigen: Phospho-RIP1 (Ser166)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RIPK1
Gene Alias: cell death protein RIP; D330015H01Rik; FLJ39204; OTTHUMP00000015955; receptor (TNFRSF)-interacting serine-threonine kinase 1; receptor interacting serine/threonine kinase 1; receptor-interacting protein 1; receptor-interacting protein kinase 1; receptor-interacting serine/threonine-protein kinase 1; Rinp; RIP; RIP1; RIP-1; RIP1 (CT); RIPK1; serine/threonine-protein kinase RIP
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 19766, 8737
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.04 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.: Q13546, Q60855
Gene Symbols: RIPK1
Immunogen: A synthetic phosphorylated peptide around S166 of human RIPK1/RIP (NP_003795.2).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-RIP1 (Ser166)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RIPK1
Gene Alias:
cell death protein RIP; D330015H01Rik; FLJ39204; OTTHUMP00000015955; receptor (TNFRSF)-interacting serine-threonine kinase 1; receptor interacting serine/threonine kinase 1; receptor-interacting protein 1; receptor-interacting protein kinase 1; receptor-interacting serine/threonine-protein kinase 1; Rinp; RIP; RIP1; RIP-1; RIP1 (CT); RIPK1; serine/threonine-protein kinase RIP
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19766, 8737
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.04 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.:
Q13546, Q60855
Gene Symbols:
RIPK1
Immunogen:
A synthetic phosphorylated peptide around S166 of human RIPK1/RIP (NP_003795.2).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-TDP-43 (Ser409, Ser410)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TARDBP
Gene Alias: 1190002A23Rik; ALS10; C85084; hypothetical protein; OTTHUMP00000002171; OTTHUMP00000002173; RCJMB04_5g9; RP4-635E18.2; TAR DNA binding protein; TAR DNA binding protein L homeolog; TAR DNA-binding protein 43; TAR DNA-binding protein-43; tardbp; tardbp.L; Tdp43; TDP-43; wu:fb77f02; wu:fc52g10; XELAEV_18035188mg
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23435
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Dot Blot, Western Blot
Concentration: 1.01 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Accession No.: Q13148
Gene Symbols: TARDBP
Immunogen: A synthetic phosphorylated peptide around S409 & S410 of human TDP-43/TARDB (NP_031401.1).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-TDP-43 (Ser409, Ser410)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TARDBP
Gene Alias:
1190002A23Rik; ALS10; C85084; hypothetical protein; OTTHUMP00000002171; OTTHUMP00000002173; RCJMB04_5g9; RP4-635E18.2; TAR DNA binding protein; TAR DNA binding protein L homeolog; TAR DNA-binding protein 43; TAR DNA-binding protein-43; tardbp; tardbp.L; Tdp43; TDP-43; wu:fb77f02; wu:fc52g10; XELAEV_18035188mg
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23435
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Dot Blot, Western Blot
Concentration:
1.01 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Accession No.:
Q13148
Gene Symbols:
TARDBP
Immunogen:
A synthetic phosphorylated peptide around S409 & S410 of human TDP-43/TARDB (NP_031401.1).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-PKR (Thr446)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: EIF2AK2
Gene Alias: 2310047A08Rik; 4732414G15Rik; AI467567; AI747578; double stranded RNA activated protein kinase; dsRNA-activated kinase; EC 2.7.11.1; eIF-2 alpha; eIF2a Kinase; eIF-2A protein kinase 2; EIF2AK1; EIF2AK2; eukaryotic translation initiation factor 2 alpha kinase 2; eukaryotic translation initiation factor 2-alpha kinase 2; IFN- type I-induced and dsRNA-activated kinase; IFN-induced and double-stranded RNA-activated kinase; interferon-induced, double-stranded RNA-activated protein kinase; interferon-inducible elF2alpha kinase; interferon-inducible RNA-dependent protein kinase; MGC126524; OTTHUMP00000201320; P1/eIF-2A protein kinase; p68 kinase; PKR; PPP1R83; Prkr; protein kinase R; protein kinase RNA-activated; protein kinase, interferon inducible double stranded RNA dependent; Protein kinase, interferon-inducible double stranded RNA dependent; protein phosphatase 1, regulatory subunit 83; serine/threonine-protein kinase TIK; T-cell viral integration site; Tik; Tyrosine-protein kinase EIF2AK2
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 19106, 5610
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 2.62 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Accession No.: P19525, Q03963
Gene Symbols: EIF2AK2
Immunogen: A synthetic phosphorylated peptide around T446 of human PKR/EIF2AK2 (NP_002750.1).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-PKR (Thr446)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
EIF2AK2
Gene Alias:
2310047A08Rik; 4732414G15Rik; AI467567; AI747578; double stranded RNA activated protein kinase; dsRNA-activated kinase; EC 2.7.11.1; eIF-2 alpha; eIF2a Kinase; eIF-2A protein kinase 2; EIF2AK1; EIF2AK2; eukaryotic translation initiation factor 2 alpha kinase 2; eukaryotic translation initiation factor 2-alpha kinase 2; IFN- type I-induced and dsRNA-activated kinase; IFN-induced and double-stranded RNA-activated kinase; interferon-induced, double-stranded RNA-activated protein kinase; interferon-inducible elF2alpha kinase; interferon-inducible RNA-dependent protein kinase; MGC126524; OTTHUMP00000201320; P1/eIF-2A protein kinase; p68 kinase; PKR; PPP1R83; Prkr; protein kinase R; protein kinase RNA-activated; protein kinase, interferon inducible double stranded RNA dependent; Protein kinase, interferon-inducible double stranded RNA dependent; protein phosphatase 1, regulatory subunit 83; serine/threonine-protein kinase TIK; T-cell viral integration site; Tik; Tyrosine-protein kinase EIF2AK2
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19106, 5610
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
2.62 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Accession No.:
P19525, Q03963
Gene Symbols:
EIF2AK2
Immunogen:
A synthetic phosphorylated peptide around T446 of human PKR/EIF2AK2 (NP_002750.1).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-Beclin 1 (Ser15)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: BECN1
Gene Alias: 4921513J16Rik; 5430417M23Rik; APG6; Atg6; ATG6 autophagy related 6 homolog; Bcl-2-interacting protein beclin; beclin 1; beclin 1 (coiled-coil, moesin-like BCL2-interacting protein); beclin 1 (coiled-coil, myosin-like BCL2 interacting protein); beclin 1 (coiled-coil, myosin-like BCL2-interacting protein); beclin 1, autophagy related; beclin1; beclin-1; Beclin-1; beclin-1; Beclin-1-C 35 kDa; Beclin-1-C 37 kDa; becn1; Coiled-coil myosin-like BCL2-interacting protein; coiled-coil, myosin-like BCL2-interacting protein; GT197; hypothetical protein MGC73097; myosin-like BCL2 interacting protein; Protein GT197; testis secretory sperm-binding protein Li 215e; VPS30; zgc:73097
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 114558, 56208, 8678
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.63 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Accession No.: O88597, Q14457, Q91XJ1
Gene Symbols: BECN1
Immunogen: A synthetic phosphorylated peptide around S15 of human Beclin 1 (NP_003757.1).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-Beclin 1 (Ser15)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
BECN1
Gene Alias:
4921513J16Rik; 5430417M23Rik; APG6; Atg6; ATG6 autophagy related 6 homolog; Bcl-2-interacting protein beclin; beclin 1; beclin 1 (coiled-coil, moesin-like BCL2-interacting protein); beclin 1 (coiled-coil, myosin-like BCL2 interacting protein); beclin 1 (coiled-coil, myosin-like BCL2-interacting protein); beclin 1, autophagy related; beclin1; beclin-1; Beclin-1; beclin-1; Beclin-1-C 35 kDa; Beclin-1-C 37 kDa; becn1; Coiled-coil myosin-like BCL2-interacting protein; coiled-coil, myosin-like BCL2-interacting protein; GT197; hypothetical protein MGC73097; myosin-like BCL2 interacting protein; Protein GT197; testis secretory sperm-binding protein Li 215e; VPS30; zgc:73097
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
114558, 56208, 8678
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.63 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Accession No.:
O88597, Q14457, Q91XJ1
Gene Symbols:
BECN1
Immunogen:
A synthetic phosphorylated peptide around S15 of human Beclin 1 (NP_003757.1).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG