PIPA5122283

Complement C9 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5122283-Each-of-1 In Stock ₹ 18,908.76

PIPA5122283 - Each of 1

₹ 18,908.76

In Stock

Quantity

1

Base Price: ₹ 18,908.76

GST (18%): ₹ 3,403.577

Total Price: ₹ 22,312.337

Antigen

Complement C9

Classification

Polyclonal

Conjugate

Unconjugated

Gene

C9

Gene Alias

ARMD15; C9; C9D; complement C9; complement component 9; complement component C9; Complement component C9a; Complement component C9b; complement protein C9; complement protein C9 precursor

Host Species

Guinea Pig

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100009197

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

500 μg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.

P48747

Gene Symbols

C9

Immunogen

Recombinant protein Complement Component 9. The antigen corresponds to amino acid range 139-519 of the target protein.

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Rabbit

Product Type

Antibody

Isotype

IgG

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Description

  • C5b-9 membrane attack complexes are assembled from five precursor molecules in the serum
  • Proteolytic cleavage of C5 by C5 convertase generates C5b which initiates assembly of the C5b-9 complex
  • The last step of C5b-9 complex formation involves polymerization of C9 which accompanies insertion of the complex into the cell membrane
  • During formation of C5b-8 and C9 polymerization, neoantigens are generated which are unique to the C5b-9 complex and are not present on any of the individual native complex components
  • The complement regulatory proteins CD59 and complement S-protein can both prevent C5b-9 insertion into the cell membrane
  • The formed SC5b-9 complex is unable to attach to cells and is cytolytically inactive
  • C5b-9 is involved in the progression of chronic proteinuric renal disease by mediating continuous tubulointerstitial damage
  • Early tubulointerstitial injury in the remnant kidney can be improved when C5b-9 complex forming is abrogated.

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Img

Thermo Scientific

PIPA5122283

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Antigen:
Complement C9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
C9

Gene Alias:
ARMD15; C9; C9D; complement C9; complement component 9; complement component C9; Complement component C9a; Complement component C9b; complement protein C9; complement protein C9 precursor

Host Species:
Guinea Pig

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100009197

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P48747

Gene Symbols:
C9

Immunogen:
Recombinant protein Complement Component 9. The antigen corresponds to amino acid range 139-519 of the target protein.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Rabbit

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5122284

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Antigen:
Caspase 1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CASP1

Gene Alias:
CASP1; CASP-1; CASP1 nirs variant 1; caspase 1; caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase); Caspase1; caspase-1; Caspase-1 subunit p10; Caspase-1 subunit p20; ICE; IL-1 beta-converting enzyme; IL-1B converting enzyme; IL1BC; IL-1BC; IL1BCE; IL1B-convertase; interleukin 1 beta-converting enzyme; interleukin 1, beta, convertase; interleukin 1-B converting enzyme; Interleukin 1beta converting enzyme; interleukin-1 beta convertase; Interleukin-1 beta-converting enzyme; p45

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
397319

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q9N2I1

Gene Symbols:
CASP1

Immunogen:
Recombinant protein Caspase 1. The antigen corresponds to amino acid range 120-297 of the target protein.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Porcine

Product Type:
Antibody

Isotype:
IgG

Img

Fischer Scientific

PIPA5122285

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Antigen:
ADAMTS16

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ADAMTS16

Gene Alias:
a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 16; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 16; a disintegrin-like and metallopetidase (reprolysin type) with thrombospondin type 1 motif, 16; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 16; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 16 preproprotein; ADAM; ADAM metallopeptidase with thrombospondin type 1 motif 16; ADAM metallopeptidase with thrombospondin type 1 motif, 16; ADAMs; ADAM-TS 16; ADAMTS16; ADAM-TS16; ADAMTS-16; ADAMTS16s; KIAA2029; metalloendopeptidases

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
170690

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q8TE57

Gene Symbols:
ADAMTS16

Immunogen:
Leu290-Pro641 (Accession Q8TE57), with N-terminal His Tag

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Fischer Scientific

PIPA5122286

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Antigen:
ADAMTS16

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ADAMTS16

Gene Alias:
a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 16; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 16; a disintegrin-like and metallopetidase (reprolysin type) with thrombospondin type 1 motif, 16; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 16; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 16 preproprotein; ADAM; ADAM metallopeptidase with thrombospondin type 1 motif 16; ADAM metallopeptidase with thrombospondin type 1 motif, 16; ADAMs; ADAM-TS 16; ADAMTS16; ADAM-TS16; ADAMTS-16; ADAMTS16s; KIAA2029; metalloendopeptidases

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
170690

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q8TE57

Gene Symbols:
ADAMTS16

Immunogen:
Leu290-Pro641 (Accession Q8TE57), with N-terminal His Tag

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG