PIPA5142411
Furin Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5142411-Each-of-1 | In Stock | ₹ 38,758.68 |
PIPA5142411 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,758.68
GST (18%): ₹ 6,976.562
Total Price: ₹ 45,735.242
Antigen
Furin
Classification
Polyclonal
Conjugate
Unconjugated
Gene
FURIN
Gene Alias
9130404I01Rik; dibasic processing enzyme; dibasic-processing enzyme; FES upstream region; FUR; Furin; furin (paired basic amino acid cleaving enzyme); furin, membrane associated receptor protein; furin, paired basic amino acid cleaving enzyme; furin; LOW QUALITY PROTEIN: furin; Pace; Paired basic amino acid cleaving enzyme (furin); paired basic amino acid residue cleaving enzyme; paired basic amino acid residue-cleaving enzyme; Pcsk3; prohormone convertase 3; proprotein convertase subtilisin/kexin type 3; Proprotein convertase subtilisin/kexin type 3 (paired basic amino acid cleaving enzyme, furin, membrane associated receptor protein); proprotein convertase subtilisin/kexin type3; SPC1; subtilisin pro-protein processing enzyme
Host Species
Goat
Purification Method
Ammonium sulfate precipitation
Regulatory Status
RUO
Gene ID (Entrez)
5045
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Isotype
IgG
Applications
Immunocytochemistry
Concentration
0.5 mg/mL
Formulation
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.
P09958
Gene Symbols
FURIN
Immunogen
Peptide with sequence C-RTKRDVYQEPTDP.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Related Products
Description
- This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000
- Furin is a membrane-associated, calcium-dependent, serine protease that belongs to the subtilisin-like prohormone convertase (PC) family
- Members of this family of cellular enzymes cleave most prohormones and neuropeptide precursors
- Numerous other cellular proteins, some viral proteins, and bacterial toxins that are transported by the constitutive secretory pathway are also targeted for maturation by PCs
- Furin and other PC family members share structural similarities which include a heterogeneous ∽10 kDa amino-terminal proregion, a highly conserved ∽55 kDa subtilisin-like catalytic domain, and carboxyl-terminal domain that is heterogeneous in length and sequence
- These enzymes become catalytically active following proregion cleavage within the appropriate cellular compartment
- Furin is the only known PC to possess a transmembrane domain
- Cleavage of target proteins occurs at the carboxyl-terminus of the furin consensus sequence, RX(K/R)R
- It has been shown that the acidic peptide sequence, C771PSDSEEDEG780, localizes furin to the trans-Golgi-network
- Phosphorylation of serine residues within this region modulates intracellular routing of furin protein
- An additional signaling domain includes the tetrapeptide sequence, Y759KGL762, which directs internalization from the cell surface.
Compare Similar Items
Show Difference
Antigen: Furin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: FURIN
Gene Alias: 9130404I01Rik; dibasic processing enzyme; dibasic-processing enzyme; FES upstream region; FUR; Furin; furin (paired basic amino acid cleaving enzyme); furin, membrane associated receptor protein; furin, paired basic amino acid cleaving enzyme; furin; LOW QUALITY PROTEIN: furin; Pace; Paired basic amino acid cleaving enzyme (furin); paired basic amino acid residue cleaving enzyme; paired basic amino acid residue-cleaving enzyme; Pcsk3; prohormone convertase 3; proprotein convertase subtilisin/kexin type 3; Proprotein convertase subtilisin/kexin type 3 (paired basic amino acid cleaving enzyme, furin, membrane associated receptor protein); proprotein convertase subtilisin/kexin type3; SPC1; subtilisin pro-protein processing enzyme
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 5045
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Applications: Immunocytochemistry
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.: P09958
Gene Symbols: FURIN
Immunogen: Peptide with sequence C-RTKRDVYQEPTDP.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Antigen:
Furin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
FURIN
Gene Alias:
9130404I01Rik; dibasic processing enzyme; dibasic-processing enzyme; FES upstream region; FUR; Furin; furin (paired basic amino acid cleaving enzyme); furin, membrane associated receptor protein; furin, paired basic amino acid cleaving enzyme; furin; LOW QUALITY PROTEIN: furin; Pace; Paired basic amino acid cleaving enzyme (furin); paired basic amino acid residue cleaving enzyme; paired basic amino acid residue-cleaving enzyme; Pcsk3; prohormone convertase 3; proprotein convertase subtilisin/kexin type 3; Proprotein convertase subtilisin/kexin type 3 (paired basic amino acid cleaving enzyme, furin, membrane associated receptor protein); proprotein convertase subtilisin/kexin type3; SPC1; subtilisin pro-protein processing enzyme
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
5045
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Applications:
Immunocytochemistry
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P09958
Gene Symbols:
FURIN
Immunogen:
Peptide with sequence C-RTKRDVYQEPTDP.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Antigen: ARX
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ARX
Gene Alias: aristaless related homeobox; aristaless-related homeobox; aristaless-related homeobox, X-linked; ARX; arx {ECO:0000250; cancer/testis antigen 121; CT121; EIEE1; Homeobox protein ARX; ISSX; MRX29; MRX32; MRX33; MRX36; MRX38; MRX43; MRX54; MRX76; MRX87; MRXS1; PRTS; RGD1562672; UniProtKB:Q96QS3}
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 170302
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q96QS3
Gene Symbols: ARX
Immunogen: Peptide with sequence C-QVSISRSKSYREN.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Antigen:
ARX
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ARX
Gene Alias:
aristaless related homeobox; aristaless-related homeobox; aristaless-related homeobox, X-linked; ARX; arx {ECO:0000250; cancer/testis antigen 121; CT121; EIEE1; Homeobox protein ARX; ISSX; MRX29; MRX32; MRX33; MRX36; MRX38; MRX43; MRX54; MRX76; MRX87; MRXS1; PRTS; RGD1562672; UniProtKB:Q96QS3}
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
170302
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q96QS3
Gene Symbols:
ARX
Immunogen:
Peptide with sequence C-QVSISRSKSYREN.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Antigen: Cullin 3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CUL3
Gene Alias: AI467304; AW146203; Cul3; CUL-3; cullin 3; cullin-3; KIAA0617; mKIAA0617; OTTHUMP00000203839; OTTHUMP00000203840; PHA2E
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 8452
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q13618
Gene Symbols: CUL3
Immunogen: Peptide with sequence C-AQVTGSNTRKHILQ.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Antigen:
Cullin 3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CUL3
Gene Alias:
AI467304; AW146203; Cul3; CUL-3; cullin 3; cullin-3; KIAA0617; mKIAA0617; OTTHUMP00000203839; OTTHUMP00000203840; PHA2E
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
8452
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q13618
Gene Symbols:
CUL3
Immunogen:
Peptide with sequence C-AQVTGSNTRKHILQ.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Antigen: Apolipoprotein A4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: APOA4
Gene Alias: APOA4; Apoa-4; APOAIV; apo-AIV; ApoA-IV; Apolipoprotein A4; apolipoprotein AIV; apolipoprotein A-IV; MGC142154; MGC142156
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 11808
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Applications: Immunohistochemistry (Paraffin)
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.: P06728
Gene Symbols: APOA4
Immunogen: Peptide with sequence C-QETERVKEEIKKELED.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Form: Liquid
Antigen:
Apolipoprotein A4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
APOA4
Gene Alias:
APOA4; Apoa-4; APOAIV; apo-AIV; ApoA-IV; Apolipoprotein A4; apolipoprotein AIV; apolipoprotein A-IV; MGC142154; MGC142156
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
11808
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin)
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P06728
Gene Symbols:
APOA4
Immunogen:
Peptide with sequence C-QETERVKEEIKKELED.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Form:
Liquid