PIPA5142964

IL-15 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5142964-Each-of-1 In Stock ₹ 38,758.68

PIPA5142964 - Each of 1

₹ 38,758.68

In Stock

Quantity

1

Base Price: ₹ 38,758.68

GST (18%): ₹ 6,976.562

Total Price: ₹ 45,735.242

Antigen

IL-15

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IL15

Gene Alias

AI503618; il 15; Il15; IL-15; ILN; Interleukin; interleukin 15; Interleukin15; interleukin-15; MGC9721; M-IL-15

Host Species

Goat

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

3600

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.

P40933

Gene Symbols

IL15

Immunogen

Peptide with sequence C-DATLYTESDVHPS.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

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Description

  • Additional Information: This antibody is expected to recognize both reported isoforms (NP_000576.1; NP_751915.1)
  • This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000
  • IL-15 (Interleukin 15 ) is a cytokine that regulates T and natural killer cell activation and proliferation
  • IL-15 and IL-2 share many biological activities as both have been found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity
  • The number of CD8+ memory cells is shown to be controlled by a balance between IL-15 and IL-2
  • IL-15 induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6
  • In mouse, studies suggest that IL-15 may increase the expression of apoptosis inhibitor Bcl-xL, possibly through the transcription activation activity of STAT6, and thus prevent apoptosis
  • IL-15 plays an important role in the growth and differentiation of T and B lymphocytes, natural killer cells, macrophages, and monocytes as well as activation of a number of important intracellular signaling molecules
  • As such, IL-15 could be essential for the immune responses, allograft rejection, and the pathogenesis of autoimmune diseases
  • Further, IL-15 is a widely expressed pro-inflammatory cytokine and has been shown to play a role in several inflammatory disorders, including rheumatoid arthritis, psoriasis and pulmonary inflammatory diseases
  • Emerging data suggest that IL-15 may serve as a good therapeutic target, as there appears to be a beneficial effect of IL-15 neutralization in models of psoriasis and diabetes.

Compare Similar Items

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Thermo Scientific

PIPA5142964

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Antigen:
IL-15

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IL15

Gene Alias:
AI503618; il 15; Il15; IL-15; ILN; Interleukin; interleukin 15; Interleukin15; interleukin-15; MGC9721; M-IL-15

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
3600

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P40933

Gene Symbols:
IL15

Immunogen:
Peptide with sequence C-DATLYTESDVHPS.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

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PIPA5142967

--


Antigen:
CTGF

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CCN2

Gene Alias:
2-Nov; betaIG-M2; CCN family member 2; Ccn2; Cellular communication network factor 2; connective tissue growth factor; connective tissue growth factor precursor; Connective tissue growth factor precursor (CTGF) (FISP-12 protein) (Hypertrophic chondrocyte-specific protein 24); connective tissue growth-related protein; CTGF; CTGF protein; CTGRP; fibroblast inducible secreated protein; fibroblast inducible secreted protein; Fisp12; fisp-12; Hcs24; H-CTGF; hypertrophic chondrocyte-specific gene product 24; hypertrophic chondrocyte-specific protein 24; IBP-8; IGF-binding protein 8; IGFBP8; IGFBP-8; Insulin-like growth factor-binding protein 8; MGC102839; NOV2; Protein FISP-12; similar to connective tissue growth factor precursor

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
14219, 1490

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P29268, P29279

Gene Symbols:
CCN2

Immunogen:
Peptide with sequence RSGESFQSSCKYQ.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid

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PIPA5142968

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Antigen:
KIM-1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Havcr1

Gene Alias:
AI503787; CD365; HAVCR; HAVCR1; HAVcr-1; Hepatitis A virus cellular receptor 1; hepatitis A virus cellular receptor 1 homolog; Kidney injury molecule 1; Kim1; KIM-1; T cell immunoglobin domain and mucin domain protein 1; t cell immunoglobulin and mucin domain-containing protein 1; T cell membrane protein 1; T-cell immunoglobulin and mucin domain containing 1; T-cell immunoglobulin and mucin domain-containing protein 1; T-cell immunoglobulin mucin family member 1; T-cell immunoglobulin mucin receptor 1; T-cell membrane protein 1; TIM; TIM1; TIM-1; TIMD1; TIMD-1

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
26762

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q96D42

Gene Symbols:
Havcr1

Immunogen:
Peptide with sequence C-THVTYRKDTRYK.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

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PIPA5142972

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Antigen:
ENC1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ENC1

Gene Alias:
CCL28; ectodermal-neural cortex (with BTB-like domain); ectodermal-neural cortex 1; ectodermal-neural cortex 1 (with BTB domain); ectodermal-neural cortex 1 (with BTB-like domain); Ectoderm-neural cortex protein 1; Enc1; ENC-1; FLJ39259; kelch-like 35; kelch-like 37; kelch-like family member 37; kelch-like protein 37; KLHL35; KLHL37; NRPB; Nuclear matrix protein NRP/B; nuclear restrict protein in brain; nuclear restricted protein, BTB domain-like (brain); p53-induced gene 10 protein; PIG10; si:dkey-35i22.1; TP53I10; tumor protein p53 inducible protein 10

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
294674, 8507

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O14682

Gene Symbols:
ENC1

Immunogen:
Peptide with sequence TSVSHDKLPKVQC.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Form:
Liquid