PIPA5143361

Phospho-IRS1 (Ser307) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5143361-Each-of-1 In Stock ₹ 37,903.08

PIPA5143361 - Each of 1

₹ 37,903.08

In Stock

Quantity

1

Base Price: ₹ 37,903.08

GST (18%): ₹ 6,822.554

Total Price: ₹ 44,725.634

Antigen

Phospho-IRS1 (Ser307)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IRS1

Gene Alias

G972R; HIRS-1; Insulin receptor substrate 1; IRS1; IRS-1; IRS1IRM; pp185

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16367, 25467, 3667

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1.51 mg/mL

Formulation

PBS with 1% BSA, 20% glycerol and 0.025% Proclin 300; pH 7

Gene Accession No.

P35568, P35569, P35570

Gene Symbols

IRS1

Immunogen

Carrier-protein conjugated synthetic peptide surrounding phospho Ser307 of human IRS1. The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Store as concentrated solution
  • Centrifuge briefly prior to opening vial
  • Positive control: C2C12 (100 nM Insulin treatment for 30 min)
  • IRS-1, a major substrate of the insulin receptor, is phosphorylated in response to stimulation of cells by insulin, insulin-like growth factor 1 (IGF-1) and interleukin 4 (IL-4)
  • IRS-1 is phosphorylated on serine, threonine and tyrosine residues in a variety of tissues
  • An insulin-sensitive serine/threonine kinase casein kinase II mediates a portion of the insulin-stimulated serine/threonine phosphorylation of overexpressed IRS-1 in vivo
  • Thr 502 is identified as the major casein kinase II-catalyzed phosphorylation site in rat IRS-1, and Ser 99 is an additional phosphorylation site catalyzed by casein kinase II
  • Thus, casein kinase II-catalyzed phosphorylation of IRS-1 may be a component of the intracellular insulin signaling cascade
  • IRS-1 contains three putative binding sites for 14-3-3 (Ser 270, Ser 374 and Ser 641) and the motif around Ser 270 is located in the phosphortyrosine binding domain of IRS-1, which is responsible for the interaction with the insulin receptor.

Compare Similar Items

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Thermo Scientific

PIPA5143361

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Antigen:
Phospho-IRS1 (Ser307)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IRS1

Gene Alias:
G972R; HIRS-1; Insulin receptor substrate 1; IRS1; IRS-1; IRS1IRM; pp185

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16367, 25467, 3667

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.51 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% Proclin 300; pH 7

Gene Accession No.:
P35568, P35569, P35570

Gene Symbols:
IRS1

Immunogen:
Carrier-protein conjugated synthetic peptide surrounding phospho Ser307 of human IRS1. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5143362

--


Antigen:
Phospho-PKC epsilon (Ser729)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRKCE

Gene Alias:
5830406C15Rik; MGC125656; MGC125657; nPKC-epsilon; PKC e; PKC[e]; Pkce; Pkcea; PKCepsilon; PRKCE; PRKCH; protein kinase C; protein kinase C epsilon; protein kinase C epsilon type; protein kinase C, epsilon; protein kinase C, eta; R75156

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18754, 29340, 5581

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.17 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% Proclin 300; pH 7

Gene Accession No.:
P09216, P16054, Q02156

Gene Symbols:
PRKCE

Immunogen:
Carrier-protein conjugated synthetic peptide surrounding phospho Ser729 of human PKC epsilon. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5143364

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Antigen:
Phospho-Tau (Thr181)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAPT

Gene Alias:
AI413597; AW045860; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; map tau; Mapt; MAPTL; MGC138549; microtubule associated protein tau; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; microtubules; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; neurofibrillary tangles; Neuronal Marker; paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; tau protein; Tau-4; Tau5; Unknown (protein for MGC:134287)

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17762, 29477, 4137

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.14 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% Proclin 300; pH 7

Gene Accession No.:
P10636, P10637, P19332

Gene Symbols:
MAPT

Immunogen:
Carrier-protein conjugated synthetic peptide surrounding phospho Thr181 of human Tau. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5143365

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Antigen:
Gad1b

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
67 kDa glutamic acid decarboxylase; 67kDa glutamate decarboxylase 1; CPSQ1; EGK_04525; EP10; FLJ45882; GAD; GAD 1; GAD 67; GAD1; Gad-1; GAD25; GAD44; Gad67; GAD-67; Glutamate decarboxylase 1; Glutamate decarboxylase 1 (brain); glutamate decarboxylase 1 (brain, 67kDa); glutamate decarboxylase 1 isoform GAD67; glutamate decarboxylase 1 variant GAD67NT; glutamate decarboxylase 67 kDa isoform; GLUTAMATE DECARBOXYLASE, 67 KD ISOFORM (GAD-67) (67 KD GLUTAMIC ACID DECARBOXYLASE); glutamic acid decarboxylase; glutamic acid decarboxylase 1; glutamic acid decarboxylase isoform 67; OTTHUMP00000041055; SCP

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Western Blot

Concentration:
0.53 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
The immunogen used to generate this antibody corresponds to zebrafish GAD67

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Zebrafish

Product Type:
Antibody

Isotype:
IgG