PIPA5143425
CXCR4b Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5143425-Each-of-1 | In Stock | ₹ 37,560.84 |
PIPA5143425 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,560.84
GST (18%): ₹ 6,760.951
Total Price: ₹ 44,321.791
Antigen
CXCR4b
Classification
Polyclonal
Conjugate
Unconjugated
Gene Alias
b2b220Clo; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; CD antigen CD184; CD184; CD184 antigen; chemokine (C-X-C motif) receptor 4; chemokine (C-X-C) receptor 4; chemokine receptor; chemokine receptor (LCR1); chemokine receptor 4; chemokine receptor CXCR4; Cmkar4; CXC; CXC chemokine receptor; C-X-C chemokine receptor type 4; CXC motif chemokine; C-X-C motif chemokine receptor 4; CXCR4; CXC-R4; CXCR-4; D2S201E; FB22; Fusin; HM89; HSY3RR; HUMSTR; LAP3; LAP-3; LCR1; LESTR; Leukocyte-derived seven transmembrane domain receptor; leukocyte-expressed seven-transmembrane-domain; lipopolysaccharide-associated protein 3; LPS-associated protein 3; neuropeptide Y receptor Y3; neuropeptide Y3 receptor; NPY3R; NPYR; NPYRL; NPYY3R; PB-CKR; PBSF/SDF-1; pre-B-cell-derived chemokine receptor; SDF-1 receptor; Sdf1r; seven transmembrane helix receptor; seven-transmembrane-segment receptor, spleen; stromal cell-derived factor 1 receptor; WHIM; WHIMS
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of zebrafish Cxcr4b. The exact sequence is proprietary.
Quantity
100 μL
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
2.22 mg/mL
Formulation
PBS with 20% glycerol and 0.025% Proclin 300; pH 7
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Target Species
Zebrafish
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Store as concentrated solution
- Centrifuge briefly prior to opening vial
- Positive control: Whole zebrafish
- CXCR4 (Fusin, LESTR, HUMSTR) is a member of the G-protein-coupled chemokine receptor family with seven membrane-spanning domains, and functions as a co-receptor for X4 HIV-1 entry into CD4+ cells
- CXCR4 has been proved to be the co-receptor for HIV-2's binding to CD4 through envelope glycoprotein gp 120 and promotes Env-mediated fusion of the virus
- In other cases, CXCR4 can even function as the only receptor for HIV-2's binding to the CD4 host cells
- CXCR4 is the receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation
- CXCR4 acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels
- Also, CXCR4 is involved in hematopoiesis and in cardiac ventricular septum formation, and plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells
- In the CNS, CXCR4 could mediate hippocampal-neuron survival and is involved in cerebellar development
- CXCR4 binds bacterial lipopolysaccharide (LPS) and mediates LPS-induced inflammatory response, including TNF secretion by monocytes
- Antibodies to CXCR4 block HIV-1 and HIV-2 fusion and infection of human target cells
- The amino-terminal domain and the second extracellular loop of CXCR4 serve as HIV biding sites.
Compare Similar Items
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Antigen: CXCR4b
Classification: Polyclonal
Conjugate: Unconjugated
Gene Alias: b2b220Clo; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; CD antigen CD184; CD184; CD184 antigen; chemokine (C-X-C motif) receptor 4; chemokine (C-X-C) receptor 4; chemokine receptor; chemokine receptor (LCR1); chemokine receptor 4; chemokine receptor CXCR4; Cmkar4; CXC; CXC chemokine receptor; C-X-C chemokine receptor type 4; CXC motif chemokine; C-X-C motif chemokine receptor 4; CXCR4; CXC-R4; CXCR-4; D2S201E; FB22; Fusin; HM89; HSY3RR; HUMSTR; LAP3; LAP-3; LCR1; LESTR; Leukocyte-derived seven transmembrane domain receptor; leukocyte-expressed seven-transmembrane-domain; lipopolysaccharide-associated protein 3; LPS-associated protein 3; neuropeptide Y receptor Y3; neuropeptide Y3 receptor; NPY3R; NPYR; NPYRL; NPYY3R; PB-CKR; PBSF/SDF-1; pre-B-cell-derived chemokine receptor; SDF-1 receptor; Sdf1r; seven transmembrane helix receptor; seven-transmembrane-segment receptor, spleen; stromal cell-derived factor 1 receptor; WHIM; WHIMS
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of zebrafish Cxcr4b. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 2.22 mg/mL
Formulation: PBS with 20% glycerol and 0.025% Proclin 300; pH 7
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Target Species: Zebrafish
Product Type: Antibody
Isotype: IgG
Antigen:
CXCR4b
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene Alias:
b2b220Clo; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; CD antigen CD184; CD184; CD184 antigen; chemokine (C-X-C motif) receptor 4; chemokine (C-X-C) receptor 4; chemokine receptor; chemokine receptor (LCR1); chemokine receptor 4; chemokine receptor CXCR4; Cmkar4; CXC; CXC chemokine receptor; C-X-C chemokine receptor type 4; CXC motif chemokine; C-X-C motif chemokine receptor 4; CXCR4; CXC-R4; CXCR-4; D2S201E; FB22; Fusin; HM89; HSY3RR; HUMSTR; LAP3; LAP-3; LCR1; LESTR; Leukocyte-derived seven transmembrane domain receptor; leukocyte-expressed seven-transmembrane-domain; lipopolysaccharide-associated protein 3; LPS-associated protein 3; neuropeptide Y receptor Y3; neuropeptide Y3 receptor; NPY3R; NPYR; NPYRL; NPYY3R; PB-CKR; PBSF/SDF-1; pre-B-cell-derived chemokine receptor; SDF-1 receptor; Sdf1r; seven transmembrane helix receptor; seven-transmembrane-segment receptor, spleen; stromal cell-derived factor 1 receptor; WHIM; WHIMS
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of zebrafish Cxcr4b. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
2.22 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% Proclin 300; pH 7
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Target Species:
Zebrafish
Product Type:
Antibody
Isotype:
IgG
Antigen: OCT4
Classification: Polyclonal
Conjugate: Unconjugated
Gene Alias: 2-Oct; 3-Oct; 4-Oct; cb197; chunp6868; DADB-104B20.2; etID49452.21; gp9; gp-9; HGNC:9221; homeobox protein; lymphoid-restricted immunoglobulin octamer-binding protein NF-A2; MGC22487; NF-A3; Oct2; Oct-2; Oct2a; Oct2b; OCT3; Oct-3; Oct3/4; Oct-3/4; OCT4; Oct-4; Octamer-binding protein 2; octamer-binding protein 3; Octamer-binding protein 4; octamer-binding transcription factor 2; Octamer-binding transcription factor 3; OTF2; OTF-2; OTF3; Otf-3; Otf3g; Otf3-rs7; Otf4; Otf-4; OTTHUMP00000221150; OTTHUMP00000221151; POU class 2 homeobox 2; POU class 5 homeobox 1; POU class 5 homeobox 1 transcript variant OCT4B1; POU class 5 homeobox 1 transcript variant OCT4B2; POU class 5 homeobox 1 transcript variant OCT4B3; POU class 5 homeobox 1 transcript variant OCT4B4; POU class 5 homeobox 1 transcript variant OCT4B5; POU class 5 homeobox 1 transcript variant OCT4B6; POU domain class 5 transcription factor 1; POU domain gene 2; POU domain protein 2; POU domain transcription factor OCT4; POU domain,
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of zebrafish Pou5f3 (Oct4). The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 2.24 mg/mL
Formulation: PBS with 20% glycerol and 0.025% Proclin 300; pH 7
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Target Species: Zebrafish
Product Type: Antibody
Isotype: IgG
Antigen:
OCT4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene Alias:
2-Oct; 3-Oct; 4-Oct; cb197; chunp6868; DADB-104B20.2; etID49452.21; gp9; gp-9; HGNC:9221; homeobox protein; lymphoid-restricted immunoglobulin octamer-binding protein NF-A2; MGC22487; NF-A3; Oct2; Oct-2; Oct2a; Oct2b; OCT3; Oct-3; Oct3/4; Oct-3/4; OCT4; Oct-4; Octamer-binding protein 2; octamer-binding protein 3; Octamer-binding protein 4; octamer-binding transcription factor 2; Octamer-binding transcription factor 3; OTF2; OTF-2; OTF3; Otf-3; Otf3g; Otf3-rs7; Otf4; Otf-4; OTTHUMP00000221150; OTTHUMP00000221151; POU class 2 homeobox 2; POU class 5 homeobox 1; POU class 5 homeobox 1 transcript variant OCT4B1; POU class 5 homeobox 1 transcript variant OCT4B2; POU class 5 homeobox 1 transcript variant OCT4B3; POU class 5 homeobox 1 transcript variant OCT4B4; POU class 5 homeobox 1 transcript variant OCT4B5; POU class 5 homeobox 1 transcript variant OCT4B6; POU domain class 5 transcription factor 1; POU domain gene 2; POU domain protein 2; POU domain transcription factor OCT4; POU domain,
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of zebrafish Pou5f3 (Oct4). The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
2.24 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% Proclin 300; pH 7
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Target Species:
Zebrafish
Product Type:
Antibody
Isotype:
IgG
Antigen: SOX4a
Classification: Polyclonal
Conjugate: Unconjugated
Gene Alias: AA682046; ecotropic viral integration site 16; EVI16; SOX4; Sox-4; SRY (sex determining region Y)-box 4; SRY box 4; SRY-box 4; SRY-box containing gene 4; SRY-box transcription factor 4; SRY-related HMG-box gene 4; transcription factor SOX-4
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of zebrafish Sox4a. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 20% glycerol and 0.025% Proclin 300; pH 7
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Target Species: Zebrafish
Product Type: Antibody
Isotype: IgG
Antigen:
SOX4a
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene Alias:
AA682046; ecotropic viral integration site 16; EVI16; SOX4; Sox-4; SRY (sex determining region Y)-box 4; SRY box 4; SRY-box 4; SRY-box containing gene 4; SRY-box transcription factor 4; SRY-related HMG-box gene 4; transcription factor SOX-4
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of zebrafish Sox4a. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% Proclin 300; pH 7
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Target Species:
Zebrafish
Product Type:
Antibody
Isotype:
IgG
Antigen: SOX4b
Classification: Polyclonal
Conjugate: Unconjugated
Gene Alias: AA682046; ecotropic viral integration site 16; EVI16; SOX4; Sox-4; SRY (sex determining region Y)-box 4; SRY box 4; SRY-box 4; SRY-box containing gene 4; SRY-box transcription factor 4; SRY-related HMG-box gene 4; transcription factor SOX-4
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of zebrafish Sox4b. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1.04 mg/mL
Formulation: PBS with 20% glycerol and 0.025% Proclin 300; pH 7
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Target Species: Zebrafish
Product Type: Antibody
Isotype: IgG
Antigen:
SOX4b
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene Alias:
AA682046; ecotropic viral integration site 16; EVI16; SOX4; Sox-4; SRY (sex determining region Y)-box 4; SRY box 4; SRY-box 4; SRY-box containing gene 4; SRY-box transcription factor 4; SRY-related HMG-box gene 4; transcription factor SOX-4
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of zebrafish Sox4b. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1.04 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% Proclin 300; pH 7
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Target Species:
Zebrafish
Product Type:
Antibody
Isotype:
IgG