PIPA5143677
Phospho-CXCR4 (Ser324, Ser325) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5143677-Each-of-1 | In Stock | ₹ 44,106.18 |
PIPA5143677 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,106.18
GST (18%): ₹ 7,939.112
Total Price: ₹ 52,045.292
Antigen
Phospho-CXCR4 (Ser324, Ser325)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Cxcr4
Gene Alias
b2b220Clo; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; CD antigen CD184; CD184; CD184 antigen; chemokine (C-X-C motif) receptor 4; chemokine (C-X-C) receptor 4; chemokine receptor; chemokine receptor (LCR1); chemokine receptor 4; chemokine receptor CXCR4; Cmkar4; CXC; CXC chemokine receptor; C-X-C chemokine receptor type 4; CXC motif chemokine; C-X-C motif chemokine receptor 4; CXCR4; CXC-R4; CXCR-4; D2S201E; FB22; Fusin; HM89; HSY3RR; HUMSTR; LAP3; LAP-3; LCR1; LESTR; Leukocyte-derived seven transmembrane domain receptor; leukocyte-expressed seven-transmembrane-domain; lipopolysaccharide-associated protein 3; LPS-associated protein 3; neuropeptide Y receptor Y3; neuropeptide Y3 receptor; NPY3R; NPYR; NPYRL; NPYY3R; PB-CKR; PBSF/SDF-1; pre-B-cell-derived chemokine receptor; SDF-1 receptor; Sdf1r; seven transmembrane helix receptor; seven-transmembrane-segment receptor, spleen; stromal cell-derived factor 1 receptor; WHIM; WHIMS
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
12767, 60628, 7852
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot
Concentration
Lot-Specific
Formulation
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.
O08565, P61073, P70658
Gene Symbols
Cxcr4
Immunogen
Phospho-CXCR4 (Ser-324/Ser-325) synthetic peptide (coupled to carrier protein) corresponds to amino acids surrounding Ser-324 and Ser-325 in the C-terminal region of human CXCR4. This sequence is conserved in mouse, rat, and chicken CXCR4, but has low homology to other CXCR family members.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Form
Liquid
Related Products
Description
- The antibody detects bands at 35, 42, 50, and 100 kDa* corresponding to various post-translationally modified forms of CXCR4 on SDS-PAGE immunoblots of human Jurkat and PC3 cells stimulated with calyculin A
- These bands co-migrate with similar bands detected with anti-CXCR4 (a.a
- 322-329) and anti-CXCR4 (a.a
- 328-338) antibodies
- CXCR4 (Fusin, LESTR, HUMSTR) is a member of the G-protein-coupled chemokine receptor family with seven membrane-spanning domains, and functions as a co-receptor for X4 HIV-1 entry into CD4+ cells
- CXCR4 has been proved to be the co-receptor for HIV-2's binding to CD4 through envelope glycoprotein gp 120 and promotes Env-mediated fusion of the virus
- In other cases, CXCR4 can even function as the only receptor for HIV-2's binding to the CD4 host cells
- CXCR4 is the receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation
- CXCR4 acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels
- Also, CXCR4 is involved in hematopoiesis and in cardiac ventricular septum formation, and plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells
- In the CNS, CXCR4 could mediate hippocampal-neuron survival and is involved in cerebellar development
- CXCR4 binds bacterial lipopolysaccharide (LPS) and mediates LPS-induced inflammatory response, including TNF secretion by monocytes
- Antibodies to CXCR4 block HIV-1 and HIV-2 fusion and infection of human target cells
- The amino-terminal domain and the second extracellular loop of CXCR4 serve as HIV biding sites.
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Antigen: Phospho-CXCR4 (Ser324, Ser325)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Cxcr4
Gene Alias: b2b220Clo; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; CD antigen CD184; CD184; CD184 antigen; chemokine (C-X-C motif) receptor 4; chemokine (C-X-C) receptor 4; chemokine receptor; chemokine receptor (LCR1); chemokine receptor 4; chemokine receptor CXCR4; Cmkar4; CXC; CXC chemokine receptor; C-X-C chemokine receptor type 4; CXC motif chemokine; C-X-C motif chemokine receptor 4; CXCR4; CXC-R4; CXCR-4; D2S201E; FB22; Fusin; HM89; HSY3RR; HUMSTR; LAP3; LAP-3; LCR1; LESTR; Leukocyte-derived seven transmembrane domain receptor; leukocyte-expressed seven-transmembrane-domain; lipopolysaccharide-associated protein 3; LPS-associated protein 3; neuropeptide Y receptor Y3; neuropeptide Y3 receptor; NPY3R; NPYR; NPYRL; NPYY3R; PB-CKR; PBSF/SDF-1; pre-B-cell-derived chemokine receptor; SDF-1 receptor; Sdf1r; seven transmembrane helix receptor; seven-transmembrane-segment receptor, spleen; stromal cell-derived factor 1 receptor; WHIM; WHIMS
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12767, 60628, 7852
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot
Concentration: Lot-Specific
Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: O08565, P61073, P70658
Gene Symbols: Cxcr4
Immunogen: Phospho-CXCR4 (Ser-324/Ser-325) synthetic peptide (coupled to carrier protein) corresponds to amino acids surrounding Ser-324 and Ser-325 in the C-terminal region of human CXCR4. This sequence is conserved in mouse, rat, and chicken CXCR4, but has low homology to other CXCR family members.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Antigen:
Phospho-CXCR4 (Ser324, Ser325)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Cxcr4
Gene Alias:
b2b220Clo; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; CD antigen CD184; CD184; CD184 antigen; chemokine (C-X-C motif) receptor 4; chemokine (C-X-C) receptor 4; chemokine receptor; chemokine receptor (LCR1); chemokine receptor 4; chemokine receptor CXCR4; Cmkar4; CXC; CXC chemokine receptor; C-X-C chemokine receptor type 4; CXC motif chemokine; C-X-C motif chemokine receptor 4; CXCR4; CXC-R4; CXCR-4; D2S201E; FB22; Fusin; HM89; HSY3RR; HUMSTR; LAP3; LAP-3; LCR1; LESTR; Leukocyte-derived seven transmembrane domain receptor; leukocyte-expressed seven-transmembrane-domain; lipopolysaccharide-associated protein 3; LPS-associated protein 3; neuropeptide Y receptor Y3; neuropeptide Y3 receptor; NPY3R; NPYR; NPYRL; NPYY3R; PB-CKR; PBSF/SDF-1; pre-B-cell-derived chemokine receptor; SDF-1 receptor; Sdf1r; seven transmembrane helix receptor; seven-transmembrane-segment receptor, spleen; stromal cell-derived factor 1 receptor; WHIM; WHIMS
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12767, 60628, 7852
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot
Concentration:
Lot-Specific
Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
O08565, P61073, P70658
Gene Symbols:
Cxcr4
Immunogen:
Phospho-CXCR4 (Ser-324/Ser-325) synthetic peptide (coupled to carrier protein) corresponds to amino acids surrounding Ser-324 and Ser-325 in the C-terminal region of human CXCR4. This sequence is conserved in mouse, rat, and chicken CXCR4, but has low homology to other CXCR family members.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Antigen: Phospho-DIAPH3 (Thr1061)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DIAPH3
Gene Alias: 4930417P13Rik; AN; AUNA1; DIA2; diap3; Diaph3; diaphanous homolog 3; diaphanous homolog 3 (Drosophila); diaphanous related formin 3; diaphanous-related formin; diaphanous-related formin 3; diaphanous-related formin-3; DKFZp434C0931; DKFZp686A13178; Drf3; FLJ34705; mDia2; mKIAA4117; NSDAN; p134MDia2; Protein diaphanous homolog 3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 290396, 56419, 81624
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Applications: Western Blot
Concentration: Lot-Specific
Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: Q9NSV4, Q9Z207
Gene Symbols: DIAPH3
Immunogen: Phospho-mDia2 (Thr-1061) synthetic peptide (coupled to KLH) corresponding to amino acid residues surrounding Thr-1061 in mouse mDia2 (Diap3). This peptide sequence is identical in rat and has 2 amino acid differences to human mDia2. The sequence has low homology to other formins.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Antigen:
Phospho-DIAPH3 (Thr1061)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DIAPH3
Gene Alias:
4930417P13Rik; AN; AUNA1; DIA2; diap3; Diaph3; diaphanous homolog 3; diaphanous homolog 3 (Drosophila); diaphanous related formin 3; diaphanous-related formin; diaphanous-related formin 3; diaphanous-related formin-3; DKFZp434C0931; DKFZp686A13178; Drf3; FLJ34705; mDia2; mKIAA4117; NSDAN; p134MDia2; Protein diaphanous homolog 3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
290396, 56419, 81624
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Applications:
Western Blot
Concentration:
Lot-Specific
Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
Q9NSV4, Q9Z207
Gene Symbols:
DIAPH3
Immunogen:
Phospho-mDia2 (Thr-1061) synthetic peptide (coupled to KLH) corresponding to amino acid residues surrounding Thr-1061 in mouse mDia2 (Diap3). This peptide sequence is identical in rat and has 2 amino acid differences to human mDia2. The sequence has low homology to other formins.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Antigen: Phospho-DIAPH2 (Ser196)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DIAPH2
Gene Alias: DIA; DIA2; Dia3; Diap2; Diaph2; diaphanous homolog 2; diaphanous homolog 2 (Drosophila); diaphanous related formin 2; diaphanous-related formin 2; diaphanous-related formin-2; diaphorase-2; DRF2; E430022I22Rik; FLJ11167; mDia3; mDia3 isoform; POF; POF2; Protein diaphanous homolog 2; RGD1564399; RP11-212B22.1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1730, 317189, 54004
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Applications: Western Blot
Concentration: Lot-Specific
Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: O60879, O70566
Gene Symbols: DIAPH2
Immunogen: Phospho-mDia3 (Ser-196) synthetic peptide (coupled to KLH) corresponding to amino acid residues surrounding Ser-196 in human mDia3 (Diap2). This peptide sequence is identical in rat and mouse mDia3, and the site is well conserved in human mDia1/Diap1 (Ser-171) and mDia2/Diap3 (Ser-202).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Antigen:
Phospho-DIAPH2 (Ser196)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DIAPH2
Gene Alias:
DIA; DIA2; Dia3; Diap2; Diaph2; diaphanous homolog 2; diaphanous homolog 2 (Drosophila); diaphanous related formin 2; diaphanous-related formin 2; diaphanous-related formin-2; diaphorase-2; DRF2; E430022I22Rik; FLJ11167; mDia3; mDia3 isoform; POF; POF2; Protein diaphanous homolog 2; RGD1564399; RP11-212B22.1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1730, 317189, 54004
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Applications:
Western Blot
Concentration:
Lot-Specific
Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
O60879, O70566
Gene Symbols:
DIAPH2
Immunogen:
Phospho-mDia3 (Ser-196) synthetic peptide (coupled to KLH) corresponding to amino acid residues surrounding Ser-196 in human mDia3 (Diap2). This peptide sequence is identical in rat and mouse mDia3, and the site is well conserved in human mDia1/Diap1 (Ser-171) and mDia2/Diap3 (Ser-202).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Antigen: Arylsulfatase B
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ARSB
Gene Alias: 1110007C02Rik; AI480648; Arsb; Arylsulfatase B; Arylsulfatase B (MPS VI); arylsulfatase B complex; arylsulfatase B regulation; arylsulfatase B structural; arylsulfatase B temporal regulation; As1; As-1; As-1r; As1-r; As-1s; As1-s; As-1t; As1-t; ASB; Asr-1; Ast-1; G4S; MPS6; N-acetylgalactosamine-4-sulfatase
Host Species: Rabbit
Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status: RUO
Gene ID (Entrez): 411
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 2 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P15848
Gene Symbols: ARSB
Immunogen: KLH conjugated synthetic peptide between 464-493 amino acids from the C-terminal region of human ARSB
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Antigen:
Arylsulfatase B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ARSB
Gene Alias:
1110007C02Rik; AI480648; Arsb; Arylsulfatase B; Arylsulfatase B (MPS VI); arylsulfatase B complex; arylsulfatase B regulation; arylsulfatase B structural; arylsulfatase B temporal regulation; As1; As-1; As-1r; As1-r; As-1s; As1-s; As-1t; As1-t; ASB; Asr-1; Ast-1; G4S; MPS6; N-acetylgalactosamine-4-sulfatase
Host Species:
Rabbit
Purification Method:
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status:
RUO
Gene ID (Entrez):
411
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
2 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P15848
Gene Symbols:
ARSB
Immunogen:
KLH conjugated synthetic peptide between 464-493 amino acids from the C-terminal region of human ARSB
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid