PIPA5143501

Cas9 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5143501-Each-of-1 In Stock ₹ 1,40,831.76

PIPA5143501 - Each of 1

₹ 1,40,831.76

In Stock

Quantity

1

Base Price: ₹ 1,40,831.76

GST (18%): ₹ 25,349.717

Total Price: ₹ 1,66,181.477

Antigen

Cas9

Classification

Polyclonal

Conjugate

Unconjugated

Gene Alias

cas9; CASP 9; Caspase9; Caspase-9 precursor; CASPASE-9c; CRISPR9; CRISPR-Cas9; CTD; OTTHUMP00000002324; RNCASP9; RP11-265F14.3; s aureus

Immunogen

CAS9 from S. aureus expressed in and purified from E. coli

Regulatory Status

RUO

Target Species

Bacteria

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration

Conc. Not Determined

Formulation

whole serum with no preservative

Host Species

Rabbit

Quantity

500 μL

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Cas9 is an RNA-guided DNA endonuclease enzyme associated with the CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) adaptive immunity system in bacteria and genetic engineering
  • The system is unique and flexible due to its dependence on RNA as the element that targets the nuclease to a desired DNA sequence
  • It can be used to induce indel mutations, specific sequence replacements/insertions, and large deletions or genomic rearrangements at any desired location in the genome
  • In addition, Cas9 can also be used to mediate upregulation of specific endogenous genes or to alter histone modifications or DNA methylation
  • Cas9 may be derived from Streptococcus pyogenes (SpCas9) or Staphylococcus aureus (SaCas9)
  • SaCas9 has a number of properties that make it advantageous for genome editing, including its small size, high efficiency, nickase activity, and apparent specificity
  • SaCas9 principally recognizes an NNGRRT protospacer adjacent motif (PAM) and cleaves target DNA at rates comparable to SpCas9 with an ideal spacer lengths of 24 to 20 nucleotides
  • In comparison to SpCas9, SaCas9 is smaller (1368 AA versus 1053 AA) and generates indels at a comparable rate when directed against target DNA with the mutually permissive NGGRRT PAM
  • This makes it the preferred enzyme for all-in-one delivery of Cas9 and multiple gRNA expression cassettes with Adeno-associated vectors.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5143501

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Antigen:
Cas9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene Alias:
cas9; CASP 9; Caspase9; Caspase-9 precursor; CASPASE-9c; CRISPR9; CRISPR-Cas9; CTD; OTTHUMP00000002324; RNCASP9; RP11-265F14.3; s aureus

Immunogen:
CAS9 from S. aureus expressed in and purified from E. coli

Regulatory Status:
RUO

Target Species:
Bacteria

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with no preservative

Host Species:
Rabbit

Quantity:
500 μL

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIPA5143502

--


Antigen:
Cas9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene Alias:
cas9; CASP 9; Caspase9; Caspase-9 precursor; CASPASE-9c; CRISPR9; CRISPR-Cas9; CTD; OTTHUMP00000002324; RNCASP9; RP11-265F14.3; s aureus

Immunogen:
N-terminal region, amino acids 1-608 and C-terminal region, amino acids 814-1372 of CAS9 sequence CDJ55032.1 from S. pyogenes, expressed in and purified from E. coli

Regulatory Status:
RUO

Target Species:
Bacteria

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 5mM sodium azide

Host Species:
Rabbit

Quantity:
500 μL

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIPA5143503

--


Antigen:
CNPase

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene Alias:
2', 3' cyclic nucleotide 3' phosphohydrolase; 2',3'-cyclic nucleotide 3' phosphodiesterase; 2',3'-cyclic nucleotide 3' phosphodiesterase; 2',3'-cyclic-nucleotide 3'-phosphodiesterase; 2',3'-cyclic-nucleotide 3'-phosphodiesterase; CNP; Cnp1; Cnp-1; CNPase; CNPF; CNPI; CNPII; cyclic nucleotide phosphodiesterase 1

Immunogen:
Full length human recombinant protein expressed in E. coli

Regulatory Status:
RUO

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 5mM sodium azide

Host Species:
Rabbit

Quantity:
500 μL

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIPA5143505

--


Antigen:
FABP7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene Alias:
B FABP; BFABP; B-FABP; BLBP; brain lipid binding protein; brain lipid-binding protein; Brain-type fatty acid-binding protein; DKFZp547J2313; FABP 7; FABP7; FABPB; fatty acid binding protein 7; fatty acid binding protein 7, brain; fatty acid-binding protein 7; Fatty acid-binding protein, brain; fatty acid-binding protein, brain-like protein; hypothetical protein DKFZp547J2313; Mammary-derived growth inhibitor related; mammary-derived growth inhibitor-related; MRG; OTTHUMP00000017119; RP11-548E19.1

Immunogen:
Recombinant full length human FABP7 expressed in and purified from E. coli.

Regulatory Status:
RUO

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 5mM sodium azide

Host Species:
Rabbit

Quantity:
500 μL

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid