PIPA5143563

Cas9 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5143563-Each-of-1 In Stock ₹ 41,026.02

PIPA5143563 - Each of 1

₹ 41,026.02

In Stock

Quantity

1

Base Price: ₹ 41,026.02

GST (18%): ₹ 7,384.684

Total Price: ₹ 48,410.704

Antigen

Cas9

Classification

Polyclonal

Conjugate

Unconjugated

Gene Alias

cas9; CASP 9; Caspase9; Caspase-9 precursor; CASPASE-9c; CRISPR9; CRISPR-Cas9; CTD; OTTHUMP00000002324; RNCASP9; RP11-265F14.3; s aureus

Immunogen

C-terminal region of S. aureus CAS9 expressed in and purified from E. coli.

Regulatory Status

RUO

Target Species

Bacteria

Product Type

Antibody

Isotype

IgY

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration

Conc. Not Determined

Formulation

PBS with 0.02% sodium azide

Host Species

Chicken

Quantity

100 μL

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Form

Liquid

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Description

  • Cas9 is an RNA-guided DNA endonuclease enzyme associated with the CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) adaptive immunity system in bacteria and genetic engineering
  • The system is unique and flexible due to its dependence on RNA as the element that targets the nuclease to a desired DNA sequence
  • It can be used to induce indel mutations, specific sequence replacements/insertions, and large deletions or genomic rearrangements at any desired location in the genome
  • In addition, Cas9 can also be used to mediate upregulation of specific endogenous genes or to alter histone modifications or DNA methylation
  • Cas9 may be derived from Streptococcus pyogenes (SpCas9) or Staphylococcus aureus (SaCas9)
  • SaCas9 has a number of properties that make it advantageous for genome editing, including its small size, high efficiency, nickase activity, and apparent specificity
  • SaCas9 principally recognizes an NNGRRT protospacer adjacent motif (PAM) and cleaves target DNA at rates comparable to SpCas9 with an ideal spacer lengths of 24 to 20 nucleotides
  • In comparison to SpCas9, SaCas9 is smaller (1368 AA versus 1053 AA) and generates indels at a comparable rate when directed against target DNA with the mutually permissive NGGRRT PAM
  • This makes it the preferred enzyme for all-in-one delivery of Cas9 and multiple gRNA expression cassettes with Adeno-associated vectors.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA5143563

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Antigen:
Cas9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene Alias:
cas9; CASP 9; Caspase9; Caspase-9 precursor; CASPASE-9c; CRISPR9; CRISPR-Cas9; CTD; OTTHUMP00000002324; RNCASP9; RP11-265F14.3; s aureus

Immunogen:
C-terminal region of S. aureus CAS9 expressed in and purified from E. coli.

Regulatory Status:
RUO

Target Species:
Bacteria

Product Type:
Antibody

Isotype:
IgY

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
Conc. Not Determined

Formulation:
PBS with 0.02% sodium azide

Host Species:
Chicken

Quantity:
100 μL

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Form:
Liquid

Img

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PIPA5143564

--


Antigen:
CNPase

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene Alias:
2', 3' cyclic nucleotide 3' phosphohydrolase; 2',3'-cyclic nucleotide 3' phosphodiesterase; 2',3'-cyclic nucleotide 3' phosphodiesterase; 2',3'-cyclic-nucleotide 3'-phosphodiesterase; 2',3'-cyclic-nucleotide 3'-phosphodiesterase; CNP; Cnp1; Cnp-1; CNPase; CNPF; CNPI; CNPII; cyclic nucleotide phosphodiesterase 1

Immunogen:
Full length human recombinant protein

Regulatory Status:
RUO

Target Species:
Bovine, Equine, Human, Mouse, Porcine, Rat

Product Type:
Antibody

Isotype:
IgY

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Western Blot

Concentration:
Conc. Not Determined

Formulation:
PBS with 5mM sodium azide

Host Species:
Chicken

Quantity:
100 μL

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

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PIPA5143567

--


Antigen:
NeuN

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene Alias:
D11Bwg0517e; FLJ56884; FLJ58356; fox 1 homolog (C. elegans) 3; fox1 homolog C; Fox-1 homolog C; FOX3; FOX-3; FOX3NeuN; hexaribonucleotide binding protein 3; hexaribonucleotide binding protein 3 (HRNBP3); Hexaribonucleotide-binding protein 3; Hrnbp3; NEUN; NeuN antigen; Neuna60; neuronal nuclear antigen A60; neuronal nuclei; Neuronal nuclei antigen; RBFOX3; RFOX3; RGD1560070; RNA binding fox-1 homolog 3; RNA binding protein; RNA binding protein fox-1 homolog 3; RNA binding protein, fox-1 homolog (C. elegans) 3; RNA binding protein, fox-1 homolog 3

Immunogen:
N-terminal 100 amino acids of human FOX3 expressed in and purified from E. coli

Regulatory Status:
RUO

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgY

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Western Blot

Concentration:
Conc. Not Determined

Formulation:
PBS with 0.02% sodium azide

Host Species:
Chicken

Quantity:
100 μL

Primary or Secondary:
Primary

Content And Storage:
4° C

Form:
Liquid

Img

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PIPA5143568

--


Antigen:
GAP43

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene Alias:
Axonal membrane protein GAP-43; B-50; Basp2; brain abundant, membrane attached signal protein 2; calmodulin-binding protein P-57; Gap43; GAP-43; growth accentuating protein 43; growth associated protein 43; growth-associated protein 43; MGC156666; nerve growth-related peptide GAP43; neural phosphoprotein B-50; Neuromodulin; neuron growth-associated protein 43; neuron protein F1; PP46; Protein F1

Immunogen:
C-terminal peptide of rodent GAP43, KEDPEADQEHA coupled to KLH

Regulatory Status:
RUO

Target Species:
Bovine, Chicken, Equine, Human, Mouse, Porcine, Rat

Product Type:
Antibody

Isotype:
IgY

Applications:
Immunocytochemistry, Western Blot

Concentration:
Conc. Not Determined

Formulation:
PBS with 5mM sodium azide

Host Species:
Chicken

Quantity:
100 μL

Primary or Secondary:
Primary

Content And Storage:
4° C

Form:
Liquid