PIPA5143582

Tau Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5143582-Each-of-1 In Stock ₹ 41,026.02

PIPA5143582 - Each of 1

₹ 41,026.02

In Stock

Quantity

1

Base Price: ₹ 41,026.02

GST (18%): ₹ 7,384.684

Total Price: ₹ 48,410.704

Antigen

Tau

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MAPT

Gene Alias

AI413597; AW045860; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; map tau; Mapt; MAPTL; MGC138549; microtubule associated protein tau; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; microtubules; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; neurofibrillary tangles; Neuronal Marker; paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; tau protein; Tau-4; Tau5; Unknown (protein for MGC:134287)

Host Species

Chicken

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Bovine, Equine, Human, Mouse, Porcine, Rat

Product Type

Antibody

Isotype

IgY

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

Conc. Not Determined

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

P10636, P10637, P19332, P29172

Gene Symbols

MAPT

Immunogen

Recombinant full length version of the shortest human Tau isoform purified from E. coli.

Regulatory Status

RUO

Gene ID (Entrez)

100054638, 100738351, 17762, 281296, 29477, 4137

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Form

Liquid

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Description

  • Tau is a neuronal microtubule-associated protein found predominantly on axons
  • The function of Tau is to promote tubulin polymerization and stabilize microtubules
  • The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both
  • Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome
  • The short isoforms allow plasticity of the cytoskeleton while the longer isoforms may preferentially play a role in its stabilization
  • In its hyper-phosphorylated form, Tau is the major component of paired helical filaments (PHF), the building block of neurofibrillary lesions in Alzheimer's diseases (AD) brain
  • Hyper-phosphorylation impairs the microtubule binding function of Tau, resulting in the destabilization of microtubules in AD brains, μgtimately leading to the degeneration of the affected neurons
  • Numerous serine/threonine kinases phosphorylate Tau, including GSK-3beta, protein kinase A (PKA), cyclin-dependent kinase 5 (cdk5) and casein kinase II
  • Hyper-phosphorylated Tau is found in neurofibrillary lesions in a range and other central nervous system disorders such as Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5143582

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Antigen:
Tau

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAPT

Gene Alias:
AI413597; AW045860; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; map tau; Mapt; MAPTL; MGC138549; microtubule associated protein tau; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; microtubules; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; neurofibrillary tangles; Neuronal Marker; paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; tau protein; Tau-4; Tau5; Unknown (protein for MGC:134287)

Host Species:
Chicken

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Equine, Human, Mouse, Porcine, Rat

Product Type:
Antibody

Isotype:
IgY

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
Conc. Not Determined

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P10636, P10637, P19332, P29172

Gene Symbols:
MAPT

Immunogen:
Recombinant full length version of the shortest human Tau isoform purified from E. coli.

Regulatory Status:
RUO

Gene ID (Entrez):
100054638, 100738351, 17762, 281296, 29477, 4137

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Form:
Liquid

Img

Thermo Scientific

PIPA5143583

--


Antigen:
Tyrosine Hydroxylase

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TH

Gene Alias:
dystonia 14; DYT14; DYT5b; EC 1.14.16.2; HGNC:11782; Th; TH isoform 3; TH isoform a; th1; TH-4; The; TY3H; TYH; TYH antibody; Tyrosine 3-hydroxylase; tyrosine 3-monooxygenase; tyrosine hydroxylase

Host Species:
Chicken

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgY

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.0 mg/mL

Formulation:
PBS with 50% glycerol and 5mM sodium azide

Gene Accession No.:
P04177, P07101, P24529

Gene Symbols:
TH

Immunogen:
Full length human TH as expressed in and purified from E. coli.

Regulatory Status:
RUO

Gene ID (Entrez):
21823, 25085, 7054

Content And Storage:
4° C

Form:
Liquid

Img

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PIPA5143585

--


Antigen:
CNPase

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CNP

Gene Alias:
2', 3' cyclic nucleotide 3' phosphohydrolase; 2',3'-cyclic nucleotide 3' phosphodiesterase; 2',3'-cyclic nucleotide 3' phosphodiesterase; 2',3'-cyclic-nucleotide 3'-phosphodiesterase; 2',3'-cyclic-nucleotide 3'-phosphodiesterase; CNP; Cnp1; Cnp-1; CNPase; CNPF; CNPI; CNPII; cyclic nucleotide phosphodiesterase 1

Host Species:
Goat

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mouse, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 5mM sodium azide

Gene Accession No.:
P06623, P09543, P13233, P16330

Gene Symbols:
CNP

Immunogen:
Full length human recombinant protein expressed in and purified from E. coli

Regulatory Status:
RUO

Gene ID (Entrez):
100511587, 1267, 12799, 25275, 280752

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIPA5143586

--


Antigen:
NeuN

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RBFOX3

Gene Alias:
D11Bwg0517e; FLJ56884; FLJ58356; fox 1 homolog (C. elegans) 3; fox1 homolog C; Fox-1 homolog C; FOX3; FOX-3; FOX3NeuN; hexaribonucleotide binding protein 3; hexaribonucleotide binding protein 3 (HRNBP3); Hexaribonucleotide-binding protein 3; Hrnbp3; NEUN; NeuN antigen; Neuna60; neuronal nuclear antigen A60; neuronal nuclei; Neuronal nuclei antigen; RBFOX3; RFOX3; RGD1560070; RNA binding fox-1 homolog 3; RNA binding protein; RNA binding protein fox-1 homolog 3; RNA binding protein, fox-1 homolog (C. elegans) 3; RNA binding protein, fox-1 homolog 3

Host Species:
Goat

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 5mM sodium azide

Gene Accession No.:
A6NFN3, Q8BIF2

Gene Symbols:
RBFOX3

Immunogen:
N-terminal 100 amino acids of human Fox3 expressed in and purified from E. coli

Regulatory Status:
RUO

Gene ID (Entrez):
146713, 287847, 52897

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid