PIPA5143640

Pre-Pro-Vasopressin Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5143640-Each-of-1 In Stock ₹ 38,416.44

PIPA5143640 - Each of 1

₹ 38,416.44

In Stock

Quantity

1

Base Price: ₹ 38,416.44

GST (18%): ₹ 6,914.959

Total Price: ₹ 45,331.399

Antigen

Pre-Pro-Vasopressin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

AVP

Gene Alias

ARVP; VP

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11998, 24221, 551

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

Lot-Specific

Formulation

10mM HEPES with 100μg/mL BSA, 150mM NaCl, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

P01185, P01186, P35455

Gene Symbols

AVP

Immunogen

Synthetic peptide corresponding to key amino acid residues surrounding the cleavage sites for the human vasopressin precursor peptide, conjugated to keyhole limpet hemocyanin (KLH).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

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Description

  • Specific for locally produced levels of the ∽ 20 kDa uncleaved pre-pro-vasopressin protein
  • Immunolabeling of the uncleaved pre-pro-vasopressin protein band is completely blocked by preadsorption of the antibody with the peptide used as antigen
  • Vasopressin is a nine amino-acid peptide hormone that plays a key role in water and blood pressure homeostasis (Qureshi S., et al 2014)
  • Vasopressin is the end-product of a highly processed 164 amino acid pre-pro-peptide
  • Processing of the vasopressin pre-pro-peptide results in three distinct peptides with a 1:1:1 ratio: vasopressin, neurophysin II, and copeptin (Arroyo J.P
  • et al, 2021)
  • Vasopressin is the biologically active hormone, neurophysin II is a carrier molecule for vasopressin, and copeptin is the c-terminal glycosylated end-product
  • Vasopressin has been thought to be primarily made in the brain, and the sole source of vasopressin stimulating vasopressin V2 receptors in the kidney until recent studies (Arroyo JP, et al 2022)
  • This antibody specially detects uncleaved pre-pro-vasopressin, accurately identifying locally produced vasopressin versus peripheral uptake of hypothalamic vasopressin or related peptides (Arroyo J.P
  • et al, 2022)
  • This key research tool aided the Arroyo group in discovering immunoreactive vasopressin outside of the brain by recognizing localized vasopressin in human and mouse kidney, specifically in the distal nephron.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5143640

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Antigen:
Pre-Pro-Vasopressin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AVP

Gene Alias:
ARVP; VP

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11998, 24221, 551

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
Lot-Specific

Formulation:
10mM HEPES with 100μg/mL BSA, 150mM NaCl, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P01185, P01186, P35455

Gene Symbols:
AVP

Immunogen:
Synthetic peptide corresponding to key amino acid residues surrounding the cleavage sites for the human vasopressin precursor peptide, conjugated to keyhole limpet hemocyanin (KLH).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Img

Thermo Scientific

PIPA5143641

--


Antigen:
Phospho-c-Abl (Tyr245)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ABL1

Gene Alias:
Abelson murine leukemia oncogene; Abelson murine leukemia viral (v-abl) oncogene homolog 1; abelson murine leukemia viral oncogene homolog 1; Abelson tyrosine-protein kinase 1; Abl; Abl 1 antib; ABL proto-oncogene 1, non-receptor tyrosine kinase; Abl1; ABL2; ABLL; AI325092; ARG; B30; bcr/abl; bcr/c-abl oncogene protein; c-ABL; c-abl oncogene 1, non-receptor tyrosine kinase; c-abl oncogene 1, receptor tyrosine kinase; c-ABL1; E430008G22Rik; JTK7; p150; Proto-oncogene c-Abl; proto-oncogene tyrosine-protein kinase ABL1; RP11-83J21.1; Tyrosine kinase ARG; tyrosine-protein kinase ABL1; v-abl; v-abl Abelson murine leukemia oncogene 1; v-abl Abelson murine leukemia viral oncogene 1; v-abl Abelson murine leukemia viral oncogene homolog 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11350, 25, 311860

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Western Blot

Concentration:
Lot-Specific

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
P00519, P00520

Gene Symbols:
ABL1

Immunogen:
Phospho-c-Abl (Tyr-245) synthetic peptide (coupled to KLH) corresponding to amino acid residues around tyrosine 245 of human c-Abl. This peptide sequence has high homology to the conserved site in rat and mouse c-Abl, as well as in viral Abl and BCR-Abl fusion protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Img

Thermo Scientific

PIPA5143642

--


Antigen:
Phospho-c-Abl (Tyr412)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ABL1

Gene Alias:
Abelson murine leukemia oncogene; Abelson murine leukemia viral (v-abl) oncogene homolog 1; abelson murine leukemia viral oncogene homolog 1; Abelson tyrosine-protein kinase 1; Abl; Abl 1 antib; ABL proto-oncogene 1, non-receptor tyrosine kinase; Abl1; ABL2; ABLL; AI325092; ARG; B30; bcr/abl; bcr/c-abl oncogene protein; c-ABL; c-abl oncogene 1, non-receptor tyrosine kinase; c-abl oncogene 1, receptor tyrosine kinase; c-ABL1; E430008G22Rik; JTK7; p150; Proto-oncogene c-Abl; proto-oncogene tyrosine-protein kinase ABL1; RP11-83J21.1; Tyrosine kinase ARG; tyrosine-protein kinase ABL1; v-abl; v-abl Abelson murine leukemia oncogene 1; v-abl Abelson murine leukemia viral oncogene 1; v-abl Abelson murine leukemia viral oncogene homolog 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11350, 25, 311860

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Western Blot

Concentration:
Lot-Specific

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
P00519, P00520

Gene Symbols:
ABL1

Immunogen:
Phospho-c-Abl (Tyr-412) synthetic peptide (coupled to KLH) corresponding to amino acid residues around tyrosine 412 of human c-Abl. This peptide sequence has high homology to the conserved site in rat and mouse c-Abl, as well as in viral Abl and BCR-Abl fusion protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Img

Thermo Scientific

PIPA5143644

--


Antigen:
Phospho-alpha Actinin 4 (Tyr4)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Actn4

Gene Alias:
actinin alpha 4; ACTININ-4; actinin-Alpha-4; Actn4; alpha actinin 4; alpha-actinin-4; C77391; F-actin cross-linking protein; focal segmental glomerulosclerosis 1; FSGS; FSGS1; non-muscle alpha-actinin 4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
60595, 63836, 81

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Western Blot

Concentration:
Lot-Specific

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
O43707, P57780, Q9QXQ0

Gene Symbols:
Actn4

Immunogen:
Phospho-alpha-actinin 4 (Tyr-4) synthetic peptide (coupled to carrier protein) corresponding to amino acids in the N-terminus of human alpha-actinin 4. This sequence is well conserved in rat and mouse alpha-actinin 4, but is not conserved in other alpha-actinins.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid