PIPA5143682
Phospho-DOK1 (Ser450) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5143682-Each-of-1 | In Stock | ₹ 44,106.18 |
PIPA5143682 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,106.18
GST (18%): ₹ 7,939.112
Total Price: ₹ 52,045.292
Antigen
Phospho-DOK1 (Ser450)
Classification
Polyclonal
Concentration
Lot-Specific
Formulation
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.
P97465, Q4QQV2, Q99704
Gene Symbols
DOK1
Immunogen
Phospho-Dok1 (Ser-450) synthetic peptide (coupled to KLH) corresponds to amino acids surrounding serine 450 in human Dok1. This sequence is conserved in Dok1 from rat (Ser-449) and mouse (Ser-451). The site is not conserved in other Dok family members.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Form
Liquid
Applications
Western Blot
Clone
WB, E
Conjugate
Unconjugated
Gene
DOK1
Gene Alias
AW557123; Docking protein 1; docking protein 1, 62kDa (downstream of tyrosine kinase 1); Dok; DOK 1; DOK1; Dok-1; Downstream of tyrosine kinase 1; downstream of tyrosine kinase-1; MGC117395; MGC138860; p240; p62 dok; p62(dok); p62DOK; pp62; TLP1; TP1; TROVE domain family; TROVE1; VAULT2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
13448, 1796, 312477
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Isotype
IgG
Related Products
Description
- This antibody was cross-adsorbed to an unphosphorylated Dok1 (Ser-450) peptide before affinity purification using phospho-Dok1 (Ser-450) peptide
- The purified antibody detects a band at 62 kDa* corresponding to Dok1 in western blots of human Jurkat cells, but does not detect this band after lambda phosphatase treatment
- Similar to Dok1 (Tyr-362) antibody, this antibody also detects an 80 kDa band that has not been identified
- DOK1 (P62dok, Docking protein 1) is believed to be a mainly cytoplasmic adaptor protein which down-regulates mitogen-activated protein kinase activation, inhibits cell proliferation and transformation, and promotes cell spreading and cell migration
- DOK1 is a major substrate for many tyrosine kinases including c-kit, v-abl, vFPS, EGF, and PDGF
- Upon phosphorylation by kinases, DOK1 forms a complex with ras GTPase-activating protein
- Phosphorylation on tyrosine residues by the insulin receptor kinase results in the negative regulation of the insulin signaling pathway
- DOK1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs.
Compare Similar Items
Show Difference
Antigen: Phospho-DOK1 (Ser450)
Classification: Polyclonal
Concentration: Lot-Specific
Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: P97465, Q4QQV2, Q99704
Gene Symbols: DOK1
Immunogen: Phospho-Dok1 (Ser-450) synthetic peptide (coupled to KLH) corresponds to amino acids surrounding serine 450 in human Dok1. This sequence is conserved in Dok1 from rat (Ser-449) and mouse (Ser-451). The site is not conserved in other Dok family members.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: Western Blot
Clone: WB, E
Conjugate: Unconjugated
Gene: DOK1
Gene Alias: AW557123; Docking protein 1; docking protein 1, 62kDa (downstream of tyrosine kinase 1); Dok; DOK 1; DOK1; Dok-1; Downstream of tyrosine kinase 1; downstream of tyrosine kinase-1; MGC117395; MGC138860; p240; p62 dok; p62(dok); p62DOK; pp62; TLP1; TP1; TROVE domain family; TROVE1; VAULT2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13448, 1796, 312477
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Antigen:
Phospho-DOK1 (Ser450)
Classification:
Polyclonal
Concentration:
Lot-Specific
Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
P97465, Q4QQV2, Q99704
Gene Symbols:
DOK1
Immunogen:
Phospho-Dok1 (Ser-450) synthetic peptide (coupled to KLH) corresponds to amino acids surrounding serine 450 in human Dok1. This sequence is conserved in Dok1 from rat (Ser-449) and mouse (Ser-451). The site is not conserved in other Dok family members.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Western Blot
Clone:
WB, E
Conjugate:
Unconjugated
Gene:
DOK1
Gene Alias:
AW557123; Docking protein 1; docking protein 1, 62kDa (downstream of tyrosine kinase 1); Dok; DOK 1; DOK1; Dok-1; Downstream of tyrosine kinase 1; downstream of tyrosine kinase-1; MGC117395; MGC138860; p240; p62 dok; p62(dok); p62DOK; pp62; TLP1; TP1; TROVE domain family; TROVE1; VAULT2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13448, 1796, 312477
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Antigen: Phospho-MAPRE3 (Ser162)
Classification: Polyclonal
Concentration: Lot-Specific
Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: Q5XIT1, Q6PER3, Q9UPY8
Gene Symbols: MAPRE3
Immunogen: Phospho-EB3 (Ser-162) synthetic peptide (coupled to KLH) corresponding to amino acid residues surrounding serine 162 in human EB3. This peptide sequence is highly conserved in mouse and rat EB3, and is not conserved in EB1 and EB2.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: Western Blot
Clone: __
Conjugate: Unconjugated
Gene: MAPRE3
Gene Alias: AI790651; APC binding protein; EB1 protein family member 3; EB2; EB3; EBF3; EBF3-S; End-binding protein 3; Mapre3; microtubule associated protein RP/EB family member 3; microtubule-associated protein RP/EB family member 3; microtubule-associated protein, RP/EB family, member 3; RP3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100732, 22924, 298848
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Antigen:
Phospho-MAPRE3 (Ser162)
Classification:
Polyclonal
Concentration:
Lot-Specific
Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
Q5XIT1, Q6PER3, Q9UPY8
Gene Symbols:
MAPRE3
Immunogen:
Phospho-EB3 (Ser-162) synthetic peptide (coupled to KLH) corresponding to amino acid residues surrounding serine 162 in human EB3. This peptide sequence is highly conserved in mouse and rat EB3, and is not conserved in EB1 and EB2.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Western Blot
Clone:
__
Conjugate:
Unconjugated
Gene:
MAPRE3
Gene Alias:
AI790651; APC binding protein; EB1 protein family member 3; EB2; EB3; EBF3; EBF3-S; End-binding protein 3; Mapre3; microtubule associated protein RP/EB family member 3; microtubule-associated protein RP/EB family member 3; microtubule-associated protein, RP/EB family, member 3; RP3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100732, 22924, 298848
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Antigen: Phospho-MAPRE3 (Ser176)
Classification: Polyclonal
Concentration: Lot-Specific
Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: Q5XIT1, Q6PER3, Q9UPY8
Gene Symbols: MAPRE3
Immunogen: Phospho-EB3 (Ser-176) synthetic peptide (coupled to KLH) corresponding to amino acid residues surrounding serine 176 in human EB3. This peptide sequence is highly conserved in mouse and rat EB3. This site is conserved in EB2 but the neighboring amino acids are not well conserved.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: Western Blot
Clone: __
Conjugate: Unconjugated
Gene: MAPRE3
Gene Alias: AI790651; APC binding protein; EB1 protein family member 3; EB2; EB3; EBF3; EBF3-S; End-binding protein 3; Mapre3; microtubule associated protein RP/EB family member 3; microtubule-associated protein RP/EB family member 3; microtubule-associated protein, RP/EB family, member 3; RP3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100732, 22924, 298848
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Antigen:
Phospho-MAPRE3 (Ser176)
Classification:
Polyclonal
Concentration:
Lot-Specific
Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
Q5XIT1, Q6PER3, Q9UPY8
Gene Symbols:
MAPRE3
Immunogen:
Phospho-EB3 (Ser-176) synthetic peptide (coupled to KLH) corresponding to amino acid residues surrounding serine 176 in human EB3. This peptide sequence is highly conserved in mouse and rat EB3. This site is conserved in EB2 but the neighboring amino acids are not well conserved.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Western Blot
Clone:
__
Conjugate:
Unconjugated
Gene:
MAPRE3
Gene Alias:
AI790651; APC binding protein; EB1 protein family member 3; EB2; EB3; EBF3; EBF3-S; End-binding protein 3; Mapre3; microtubule associated protein RP/EB family member 3; microtubule-associated protein RP/EB family member 3; microtubule-associated protein, RP/EB family, member 3; RP3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100732, 22924, 298848
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Antigen: Phospho-EEF2K (Ser78)
Classification: Polyclonal
Concentration: Lot-Specific
Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: O00418, O08796, P70531
Gene Symbols: EEF2K
Immunogen: Phospho-eEF2K (Ser-78) synthetic peptide (coupled to carrier protein) corresponds to amino acids surrounding Ser-78 in human eEF2K. This sequence is well conserved in rat and mouse eEF2K, and has low homology to other proteins.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: Western Blot
Clone: __
Conjugate: Unconjugated
Gene: EEF2K
Gene Alias: C86191; Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase; calcium/calmodulin-dependent eukaryotic elongation factor-2 kinase; calmodulin-dependent protein kinase III; EC 2.7.11.20; eEF-2 kinase; Eef2k; eEF-2K; EF2K; elongation factor 2 kinase; elongation factor-2 kinase; euk; eukaroytic elongation factor 2 kinase; eukaryotic elongation factor 2 kinase; eukaryotic elongation factor-2 kinase; HSU93850; kinase eEF2K; SMEF2K
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13631, 25435, 29904
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Antigen:
Phospho-EEF2K (Ser78)
Classification:
Polyclonal
Concentration:
Lot-Specific
Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
O00418, O08796, P70531
Gene Symbols:
EEF2K
Immunogen:
Phospho-eEF2K (Ser-78) synthetic peptide (coupled to carrier protein) corresponds to amino acids surrounding Ser-78 in human eEF2K. This sequence is well conserved in rat and mouse eEF2K, and has low homology to other proteins.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Western Blot
Clone:
__
Conjugate:
Unconjugated
Gene:
EEF2K
Gene Alias:
C86191; Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase; calcium/calmodulin-dependent eukaryotic elongation factor-2 kinase; calmodulin-dependent protein kinase III; EC 2.7.11.20; eEF-2 kinase; Eef2k; eEF-2K; EF2K; elongation factor 2 kinase; elongation factor-2 kinase; euk; eukaroytic elongation factor 2 kinase; eukaryotic elongation factor 2 kinase; eukaryotic elongation factor-2 kinase; HSU93850; kinase eEF2K; SMEF2K
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13631, 25435, 29904
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG