PIPA5143752

Phospho-Profilin 1 (Ser138) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5143752-Each-of-1 In Stock ₹ 45,731.82

PIPA5143752 - Each of 1

₹ 45,731.82

In Stock

Quantity

1

Base Price: ₹ 45,731.82

GST (18%): ₹ 8,231.728

Total Price: ₹ 53,963.548

Antigen

Phospho-Profilin 1 (Ser138)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Pfn1

Gene Alias

actin binding protein; ALS18; Epididymis tissue protein Li 184a; Pfn; Pfn1; profilin 1; profilin I; Profilin-1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18643, 5216, 64303

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

Applications

Western Blot

Concentration

∽0.5 mg/mL

Formulation

PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.

P07737, P62962, P62963

Gene Symbols

Pfn1

Immunogen

Phospho-Profilin (Ser138) synthetic peptide (coupled to carrier protein) that includes amino acids surrounding Ser138 in human Profilin-1. This sequence is conserved in rat and mouse Profilin-1. The serine site has some homology to the conserved site (Ser138) in Profilin-2a and Profilin-2b, but the site is not conserved in Profiin-3 and Profilin-4.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

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Description

  • This antibody was cross-adsorbed to unphosphorylated Profilin (Ser-138) then affinity purified using Profilin (Ser-138) peptide (without carrier)
  • The antibody detects a 15 kDa band corresponding to the apparent molecular mass of Profilin-1 in human Jurkat and A431 cells, as well as rat PC12 cells
  • This reactivity is decreased by lambda phosphatase treatment, and is blocked by phospho-profilin (Ser-138) blocking peptide
  • Profilin is an ubiquitous small (12-15 kDa) phosphoinositides and poly-L-proline binding protein that plays a role in both signal transduction pathways and actin filament dynamics
  • There are two mammalian profilins with similar biochemical properties but different expression patterns
  • Profilin I appears to be highly expressed in most tissues except for skeletal muscle
  • Profilin II is predominantly expressed in brain and at lower levels in skeletal muscle, uterus and kidney
  • Profilin is a mainly cytosolic protein with higher concentrations in dynamic membrane areas like the leading edge and ruffling membranes.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5143752

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Antigen:
Phospho-Profilin 1 (Ser138)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Pfn1

Gene Alias:
actin binding protein; ALS18; Epididymis tissue protein Li 184a; Pfn; Pfn1; profilin 1; profilin I; Profilin-1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18643, 5216, 64303

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Western Blot

Concentration:
∽0.5 mg/mL

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
P07737, P62962, P62963

Gene Symbols:
Pfn1

Immunogen:
Phospho-Profilin (Ser138) synthetic peptide (coupled to carrier protein) that includes amino acids surrounding Ser138 in human Profilin-1. This sequence is conserved in rat and mouse Profilin-1. The serine site has some homology to the conserved site (Ser138) in Profilin-2a and Profilin-2b, but the site is not conserved in Profiin-3 and Profilin-4.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Img

Thermo Scientific

PIPA5143754

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Antigen:
Phospho-PTP1B (Ser50)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PTPN1

Gene Alias:
CPTP1; EC 3.1.3.48; EGK_02300; hgnc9642; KIAA0283; protein tyrosine phosphatase 1B; protein tyrosine phosphatase non-receptor type 1; protein tyrosine phosphatase, non-receptor type 1; protein tyrosine phosphatase, placental; protein-protein-tyrosine phosphatase HA2; protein-tyrosine phosphatase 1B; Protein-tyrosine phosphatase HA2; PTN1; Ptp; PTP1B; PTP-1B; ptp1b protein; PTP-HA2; Ptpn1; RP5-1121H13.2; RPTPrho; tyrosine phosphatase 1b; tyrosine-phosphatase; Tyrosine-protein phosphatase non-receptor type 1; wu:fk54h03

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19246, 24697, 5770

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Concentration:
Lot-Specific

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
P18031, P20417, P35821

Gene Symbols:
PTPN1

Immunogen:
PTP1B (Ser-50) synthetic peptide (coupled to carrier protein) corresponds to amino acids surrounding Ser-50 in human PTP1B. This sequence has significant homology to the conserved site in rat and mouse PTP1B, and has homology to conserved sites in TC-PTP and MPTP, but not other protein tyrosine phosphatase family members.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

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PIPA5143756

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Antigen:
Phospho-A-Raf/B-Raf/C-Raf (Ser446, Ser338, Ser299)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BRAF

Gene Alias:
BRAF1; CRaf; Raf1; RAFB1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
109880, 110157, 114486, 24703, 5894, 673

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Western Blot

Concentration:
Lot-Specific

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
P04049, P11345, P15056, P28028, Q99N57

Gene Symbols:
BRAF, RAF1

Immunogen:
Phospho-B-Raf (Ser-446) synthetic peptide (coupled to KLH) corresponds to amino acids surrounding serine 446 in human B-Raf. This sequence is conserved in B-Rafs from many species, and has high homology to C-Raf (Ser-338) and A-Raf (Ser-299).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Img

Thermo Scientific

PIPA5143757

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Antigen:
Phospho-A-Raf/B-Raf/C-Raf (Ser471, Ser579, Ser432)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BRAF

Gene Alias:
BRAF1; CRaf; Raf1; RAFB1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
109880, 110157, 114486, 24703, 5894, 673

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Western Blot

Concentration:
Lot-Specific

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
P04049, P11345, P15056, P28028, Q99N57

Gene Symbols:
BRAF, RAF1

Immunogen:
A synthetic peptide (coupled to KLH) corresponding to amino acid residues surrounding Ser-471 in human C-Raf. This sequence has high homology with similar regions in rat and mouse C-Raf, and has high homology to the conserved sites in B-Raf (Ser-579) and A-Raf (Ser-432).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid