PIPA517463

NEDD4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA517463-Each-of-1 In Stock ₹ 50,138.16

PIPA517463 - Each of 1

₹ 50,138.16

In Stock

Quantity

1

Base Price: ₹ 50,138.16

GST (18%): ₹ 9,024.869

Total Price: ₹ 59,163.029

Antigen

NEDD4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NEDD4

Gene Alias

AA959633; AL023035; AU019897; cell proliferation-inducing gene 53 protein; E3 ubiquitin-protein ligase NEDD4; E430025J12Rik; HECT-type E3 ubiquitin transferase NEDD4; Kiaa0093; mKIAA0093; NEDD4; NEDD-4; NEDD4 E3 ubiquitin protein ligase; Nedd4-1; Nedd4a; Neural precursor cell expressed developmentally down-regulated protein 4; neural precursor cell expressed, developmentally down-regulated 4; neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase; neural precursor cell expressed, developmentally down-regulated gene 4; neural precursor cell expressed, developmentally down-regulated gene 4a; neural precursor cell expressed, developmentally down-regulted gene 4; OTTHUMP00000217840; OTTHUMP00000217841; OTTHUMP00000217842; PIG53; receptor-potentiating factor 1; RPF1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

17999, 25489, 4734

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

6 μg/mL

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

P46934, P46935, Q62940

Gene Symbols

NEDD4

Immunogen

Synthetic peptide corresponding to human NEDD4 protein

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • It is not recommended to aliquot this antibody
  • The E3 ubiquitin-protein ligase NEDD4 is a Ubl conjugation pathway protein
  • It contains one HECT (E6AP-type E3 ubiquitin-protein ligase) domain and four WW domains
  • It is involved in the pathway leading to the degradation of VEGFR-2/KDFR, independently of its ubiquitin-ligase activity
  • It acts as a potential proto-oncogene that negatively regulates PTEN via ubiquitination, a paradigm analogous to that of Mdm2 and p53
  • It is also reported to be involved in the budding of many viruses and is the regulator of epithelial Na+ channels, which lead to arterial hypertension
  • NEDD4 protein is localized to the sarcolemmal region of muscle fibers
  • Increase in NEDD4 protein expression leads to unloaded and denervated muscles as well as a decrease in Notch1 expression
  • Hence it acts as down regulator of Notch-1 gene expression.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA517463

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Antigen:
NEDD4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NEDD4

Gene Alias:
AA959633; AL023035; AU019897; cell proliferation-inducing gene 53 protein; E3 ubiquitin-protein ligase NEDD4; E430025J12Rik; HECT-type E3 ubiquitin transferase NEDD4; Kiaa0093; mKIAA0093; NEDD4; NEDD-4; NEDD4 E3 ubiquitin protein ligase; Nedd4-1; Nedd4a; Neural precursor cell expressed developmentally down-regulated protein 4; neural precursor cell expressed, developmentally down-regulated 4; neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase; neural precursor cell expressed, developmentally down-regulated gene 4; neural precursor cell expressed, developmentally down-regulated gene 4a; neural precursor cell expressed, developmentally down-regulted gene 4; OTTHUMP00000217840; OTTHUMP00000217841; OTTHUMP00000217842; PIG53; receptor-potentiating factor 1; RPF1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17999, 25489, 4734

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
6 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P46934, P46935, Q62940

Gene Symbols:
NEDD4

Immunogen:
Synthetic peptide corresponding to human NEDD4 protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA517465

--


Antigen:
TRADD

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRADD

Gene Alias:
9130005N23Rik; AA930854; Hs.89862; Hs89862; MGC11078; TNF receptor 1 associated signal transducer; TNFR1-associated DEATH domain protein; TNFRSF1A associated via death domain; TNFRSF1A-associated via death domain; TRADD; tumor necrosis factor receptor type 1 associated death domain protein; tumor necrosis factor receptor type 1-associated DEATH domain protein; tumor necrosis factor receptor-1-associated protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
246756, 71609, 8717

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
81 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
Q15628, Q3U0V2

Gene Symbols:
TRADD

Immunogen:
Synthetic peptide corresponding to residues surrounding cysteine 138 of human TRADD

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA517467

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Antigen:
CD266

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TNFRSF12A

Gene Alias:
AI255180; C87282; CD266; FGF-inducible 14; Fgfrp2; fibroblast growth factor regulated protein 2; fibroblast growth factor-inducible immediate-early response protein 14; Fibroblast growth factor-regulated protein 2; FN14; HPIP; TNF receptor superfamily member 12A; TNFRSF12A; Tumor necrosis factor receptor superfamily member 12A; tumor necrosis factor receptor superfamily, member 12A; TweakR; TWEAK-R; Tweak-receptor; type I transmembrane protein Fn14

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27279, 302965, 51330, 617439

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
197 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
Q9CR75, Q9NP84

Gene Symbols:
TNFRSF12A

Immunogen:
Synthetic peptide corresponding to residues near the carboxy terminus of the TWEAK Receptor/Fn14

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA517468

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Antigen:
SKP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SKP1

Gene Alias:
15kDa; 2610043E24Rik; 2610206H23Rik; cyclin A/CDK2-associated p19; cyclin A/CDK2-associated protein p19; cyclin-A/CDK2-associated protein p19; EMC19; MGC34403; OCP2; OCP-2; OCP-II; OCP-II protein; organ of Corti protein 2; Organ of Corti protein II; p19A; p19Skp1; polypeptide 1-like; RNA polymerase II elongation factor-like protein; RNA polymerase II elongation factor-like protein OCP2; SIII; Skp1; Skp1a; S-phase kinase-associated protein 1; S-phase kinase-associated protein 1A; TCEB1L; transcription elongation factor B polypeptide 1-like

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21402, 287280, 6500

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Concentration:
__

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P63208, Q6PEC4, Q9WTX5

Gene Symbols:
SKP1, Skp1a

Immunogen:
Synthetic peptide corresponding to residues of human Skp1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG