Phospho-IKK alpha/beta (Ser176, Ser180) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA517593-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA517593 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
Phospho-IKK alpha/beta (Ser176, Ser180)
Classification
Polyclonal
Formulation
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.
O14920, O15111, O88351, Q60680, Q9QY78
Gene Symbols
CHUK, Ikbkb
Immunogen
Phosphopeptide corresponding to a region surrounding pSer177/181 of IKKβ
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Conjugate
Unconjugated
Gene
Ikbkb
Gene Alias
AI132552; AI256658; AIM-1; CHUK; Chuk1; component of inhibitor of nuclear factor kappa B kinase complex; conserved helix-loop-helix ubiquitous kinase; EC 2.7.11.10; Fbx24; Fbxo24; I kappa B kinase 1; i kappa-B kinase alpha; IkappaB kinase; I-kappa-B kinase 1; I-kappa-B kinase 2; IkappaB kinase alpha; I-kappa-B kinase alpha; I-kappa-B kinase-alpha; I-kappa-B-kinase beta; IkB kinase alpha subunit; IkB kinase-alpha; IkB kinase-beta; ikBKA; Ikbkb; IKK alpha; IKK[b]; IKK1; IKK2; IKK-2; IKKA; IKK-A; IKK-a kinase; IKK-alpha; Ikkb; IKK-B; IKKbeta; IKK-beta; IMD15; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; inhibitor of kappaB kinase beta; inhibitor of nuclear factor kappa B kinase beta subunit; inhibitor of nuclear factor kappa B kinase subunit beta; inhibitor of nuclear factor kappa-B kinase subunit alpha; Inhibitor of nuclear factor kappa-B kinase subunit beta; NFKBIKA; NFKBIKB; Nuclear factor NFkappaB inhibitor kinase alpha; nuclear factor NF-kappa-B inhibitor kinase alpha; Nuclear factor NF-kappa-B inhibitor kinase beta; TCF16; TCF-16; TCF17; Transcription factor 16
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1147, 12675, 16150, 309361, 3551, 84351
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- It is not recommended to aliquot this antibody
- IKK alpha/beta is encoded by CHUK (conserved helix-loop-helix ubiquitous kinase) and IKKB (inhibitor of kappa light polypeptide gene enhancer in B-cells) gene located in chromosome 10 and 8 respectively in humans
- Upon stimulation by agents that activate the NF-kB pathway such as TNF alpha, the two subunits of IKK complex, IKK alpha and IKK -beta alongside a regulator NEMO (IKK gamma) phosphorylates IkB proteins
- This targets the later for ubiquitin mediated degradation and phosphorylation of NF-kB leading to subsequent translocation to the nucleus
- Phosphorylation at serine 176 and 180 located in the activation loop causes a confirmation change that is required for the activation of the kinases.
Compare Similar Items
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Antigen: Phospho-IKK alpha/beta (Ser176, Ser180)
Classification: Polyclonal
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.: O14920, O15111, O88351, Q60680, Q9QY78
Gene Symbols: CHUK, Ikbkb
Immunogen: Phosphopeptide corresponding to a region surrounding pSer177/181 of IKKβ
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: Ikbkb
Gene Alias: AI132552; AI256658; AIM-1; CHUK; Chuk1; component of inhibitor of nuclear factor kappa B kinase complex; conserved helix-loop-helix ubiquitous kinase; EC 2.7.11.10; Fbx24; Fbxo24; I kappa B kinase 1; i kappa-B kinase alpha; IkappaB kinase; I-kappa-B kinase 1; I-kappa-B kinase 2; IkappaB kinase alpha; I-kappa-B kinase alpha; I-kappa-B kinase-alpha; I-kappa-B-kinase beta; IkB kinase alpha subunit; IkB kinase-alpha; IkB kinase-beta; ikBKA; Ikbkb; IKK alpha; IKK[b]; IKK1; IKK2; IKK-2; IKKA; IKK-A; IKK-a kinase; IKK-alpha; Ikkb; IKK-B; IKKbeta; IKK-beta; IMD15; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; inhibitor of kappaB kinase beta; inhibitor of nuclear factor kappa B kinase beta subunit; inhibitor of nuclear factor kappa B kinase subunit beta; inhibitor of nuclear factor kappa-B kinase subunit alpha; Inhibitor of nuclear factor kappa-B kinase subunit beta; NFKBIKA; NFKBIKB; Nuclear factor NFkappaB inhibitor kinase alpha; nuclear factor NF-kappa-B inhibitor kinase alpha; Nuclear factor NF-kappa-B inhibitor kinase beta; TCF16; TCF-16; TCF17; Transcription factor 16
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1147, 12675, 16150, 309361, 3551, 84351
Content And Storage: -20°C
Form: Liquid
Antigen: Phospho-PBK (Thr9)
Classification: Polyclonal
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.: Q96KB5
Gene Symbols: PBK
Immunogen: Synthetic phosphopeptide corresponding to amino acids around pThr9 of human PBK/TOPK
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: PBK
Gene Alias: 2810434B10Rik; AW538537; Cancer/testis antigen 84; CT84; D14Ertd732e; epididymis luminal protein 164; HEL164; Lymphokine-activated killer T-cell-originated protein kinase; MAPKK-like protein kinase; Nori-3; PBK; PDZ binding kinase; PDZ-binding kinase; serine/threonine protein kinase; spermatogenesis-related protein kinase; SPK; T-LAK cell-originated protein kinase; TOPK
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 55872
Content And Storage: -20°C
Form: Liquid
Antigen: PABP
Classification: Polyclonal
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.: P11940, P29341, Q9EPH8
Gene Symbols: PABPC1
Immunogen: Synthetic peptide corresponding to amino acids at the amino-terminus of human PABP1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Western Blot
Conjugate: Unconjugated
Gene: PABPC1
Gene Alias: Cytoplasmic poly(A)-binding protein 1-A; ePAB; hypothetical protein; PAB1; pabp; PABP 1; Pabp1; PABP-1; PABP-1A; PABP-1-A; PABP-A; Pabpc1; pabpc1.L; pabpc1.S; pabpc1a; pabpc1-a; pabpc1a protein; pabpc1-b; pabpc2; PabpI; PABPL1; poly A binding protein 1; poly A binding protein, cytoplasmic 1 a; poly(A) binding protein cytoplasmic 1; poly(A) binding protein, cytoplasmic 1; poly(A) binding protein, cytoplasmic 1 L homeolog; poly(A) binding protein, cytoplasmic 1 S homeolog; poly(A) binding protein, cytoplasmic 1a; poly(A) binding protein, cytoplasmic 2; poly(A)-binding protein 1; poly(A)-binding protein 1A; poly(A)-binding protein 1-A; polyadenylate-binding protein 1; Polyadenylate-binding protein 1A; Polyadenylate-binding protein 1-A; polyadenylate-binding protein 1A; poly(A) binding protein, cytoplasmic 1a; wu:fb16a02; wu:fi19b08; wu:fj12d09; wu:fj61f06; XELAEV_18033915mg; xPABP1-A; zgc:109879
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 171350, 18458, 26986
Content And Storage: -20°C
Form: Liquid