PIPA517735

Nicastrin Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA517735-Each-of-1 In Stock ₹ 42,223.86

PIPA517735 - Each of 1

₹ 42,223.86

In Stock

Quantity

1

Base Price: ₹ 42,223.86

GST (18%): ₹ 7,600.295

Total Price: ₹ 49,824.155

Antigen

Nicastrin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NCSTN

Gene Alias

9430068N19Rik; AA727311; anterior pharynx-defective 2; Aph2; ATAG1874; D1Dau13e; Kiaa0253; mKIAA0253; NCSTN; Nct; Nicastrin; OTTHUMP00000031840; UNQ1874/PRO4317

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23385, 289231, 59287

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

183 μg/mL

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

P57716, Q8CGU6, Q92542

Gene Symbols

NCSTN

Immunogen

Synthetic peptide corresponding to the carboxy-terminus of human Nicastrin

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • It is not recommended to aliquot this antibody
  • NCSTN (Nicastrin) is a gene that encodes a type I transmembrane glycoprotein that is an integral component of the multimeric gamma-secretase complex
  • The encoded protein cleaves integral membrane proteins, including Notch receptors and beta-amyloid precursor protein, and may be a stabilizing cofactor required for gamma-secretase complex assembly
  • The cleavage of beta-amyloid precursor protein yields amyloid beta peptide, the main component of the neuritic plaque and the hallmark lesion in the brains of patients with Alzheimer's disease; however, the nature of the encoded protein's role in Alzheimer's disease is not known for certain
  • Mutations in this gene are associated with familial acne inversa
  • A pseudogene of this gene is present on chromosome 21.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA517735

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Antigen:
Nicastrin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NCSTN

Gene Alias:
9430068N19Rik; AA727311; anterior pharynx-defective 2; Aph2; ATAG1874; D1Dau13e; Kiaa0253; mKIAA0253; NCSTN; Nct; Nicastrin; OTTHUMP00000031840; UNQ1874/PRO4317

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23385, 289231, 59287

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
183 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P57716, Q8CGU6, Q92542

Gene Symbols:
NCSTN

Immunogen:
Synthetic peptide corresponding to the carboxy-terminus of human Nicastrin

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA517737

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Antigen:
eIF4B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Eif4b

Gene Alias:
2310046H11Rik; AL024095; C85189; Eif4a2; EIF4B; eIF-4B; Eukaryotic translation initiation factor 4B; hCG_2014609; hypothetical protein; PRO1843

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1975, 300253, 75705

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
__

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P23588, Q8BGD9

Gene Symbols:
Eif4b

Immunogen:
Synthetic peptide corresponding to residues at the amino terminus of human eIF4B

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA517741

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Antigen:
Phospho-CrkL (Tyr207)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CRKL

Gene Alias:
1110025F07Rik; AA589403; AI325100; CRK like proto-oncogene, adaptor protein; CRKL; crkl {ECO:0000312; crk-like protein; crk-like protein {ECO:0000250; Crkol; EMBL:AAH85865.1, ECO:0000312; OTTHUMP00000198539; RGD:1308531}; UniProtKB:P46109}; v-crk avian sarcoma virus CT10 oncogene homolog-like; v-crk sarcoma virus CT10 oncogene homolog (avian)-like; v-crk sarcoma virus CT10 oncogene homolog-like

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12929, 1399, 287942

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
__

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P46109, P47941, Q5U2U2

Gene Symbols:
CRKL

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pTyr207 of human CrkL

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA517742

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Antigen:
NPM1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NPM1

Gene Alias:
B23; B23 antibody; B23NP; MGC104254; mNPM antibody; mNPM1 antibody; NO38; NO38 antibody; Npm; npm1; npm1.L; Nucleolar phosphoprotein B23; nucleolar protein B23.1; nucleolar protein B23/No38; nucleolar protein NO38; Nucleophosmin; nucleophosmin (nucleolar phosphoprotein B23, numatrin); nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog; nucleophosmin 1; nucleophosmin/nucleoplasmin family, member 1; nucleoplasmin; numatrin; numatrin antibody; testicular tissue protein Li 128; unnamed protein product; XELAEV_18020022mg

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18148, 25498, 4869

Content And Storage:
-20°C

Form:
Liquid

Applications:
ChIP Assay, Immunocytochemistry, Western Blot, Western Blot

Concentration:
21 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P06748, P13084, Q61937

Gene Symbols:
NPM1

Immunogen:
Synthetic peptide corresponding to residues surrounding the amino-terminus of human NPM

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG