PIPA517742

NPM1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA517742-Each-of-1 In Stock ₹ 41,796.06

PIPA517742 - Each of 1

₹ 41,796.06

In Stock

Quantity

1

Base Price: ₹ 41,796.06

GST (18%): ₹ 7,523.291

Total Price: ₹ 49,319.351

Antigen

NPM1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NPM1

Gene Alias

B23; B23 antibody; B23NP; MGC104254; mNPM antibody; mNPM1 antibody; NO38; NO38 antibody; Npm; npm1; npm1.L; Nucleolar phosphoprotein B23; nucleolar protein B23.1; nucleolar protein B23/No38; nucleolar protein NO38; Nucleophosmin; nucleophosmin (nucleolar phosphoprotein B23, numatrin); nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog; nucleophosmin 1; nucleophosmin/nucleoplasmin family, member 1; nucleoplasmin; numatrin; numatrin antibody; testicular tissue protein Li 128; unnamed protein product; XELAEV_18020022mg

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18148, 25498, 4869

Content And Storage

-20°C

Form

Liquid

Applications

ChIP Assay, Immunocytochemistry, Western Blot, Western Blot

Concentration

21 μg/mL

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

P06748, P13084, Q61937

Gene Symbols

NPM1

Immunogen

Synthetic peptide corresponding to residues surrounding the amino-terminus of human NPM

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • It is not recommended to aliquot this antibody
  • NPM1 (Nucleophosmin 1, B23, nutramin, NO38) is a ubiquitously expressed phosphoprotein involved in ribosome assembly/transport, cytoplasmic/nuclear trafficking, regulation of DNA polymerase alpha activity, centrosome duplication, and regulation of p53
  • NPM1 continuously shuttles between the nucleus, cytoplasm, nucleolus and chaperoning core histones from the nucleus to the cytoplasm
  • NPM1 has been shown to bind nucleic acid, prevent protein aggregation via its chaperon activities, protect enzymes during thermal denaturation, and facilitate renaturation of chemically denatured proteins
  • In its cellular structure role, there is evidence suggesting NPM1 is associated with the centrosome, and is the substrate of CDK2/cyclin E during duplication of centrosomes (cellular division)
  • Due to the NPM1 gene interaction with several tumor-associated chromosome translocations, NPM1 is thought to be a portion of several fusion proteins: NPM-ALK, NPM-RAR, and NPM-MLF1
  • While it is not thought to be part of the transforming potential of these fusion proteins, NPM1 is believed to act as the interface for oligomerization and oncogenic conversion of these tumor promoting fusion proteins
  • Further, NPM1 is also known to sequester the tumor suppressor RF in the nucleolus, protecting it from degradation until it is necessary
  • Dysfunction of the NPM1 protein is associated with diseases such as acute myeloid leukemia and lymphomatoid papulosis.

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PIPA517742

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Antigen:
NPM1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NPM1

Gene Alias:
B23; B23 antibody; B23NP; MGC104254; mNPM antibody; mNPM1 antibody; NO38; NO38 antibody; Npm; npm1; npm1.L; Nucleolar phosphoprotein B23; nucleolar protein B23.1; nucleolar protein B23/No38; nucleolar protein NO38; Nucleophosmin; nucleophosmin (nucleolar phosphoprotein B23, numatrin); nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog; nucleophosmin 1; nucleophosmin/nucleoplasmin family, member 1; nucleoplasmin; numatrin; numatrin antibody; testicular tissue protein Li 128; unnamed protein product; XELAEV_18020022mg

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18148, 25498, 4869

Content And Storage:
-20°C

Form:
Liquid

Applications:
ChIP Assay, Immunocytochemistry, Western Blot, Western Blot

Concentration:
21 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P06748, P13084, Q61937

Gene Symbols:
NPM1

Immunogen:
Synthetic peptide corresponding to residues surrounding the amino-terminus of human NPM

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA517747

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Antigen:
Phospho-Crk (Tyr221)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Crk

Gene Alias:
Adapter molecule crk; avian sarcoma virus CT10 (v-crk) oncogene homolog; c-Crk; CRK; CRK proto-oncogene, adaptor protein; CRK1; Crk3; Crk-I; CRKII; Crk-II; CrkIII; Crk-III; Crko; CSAID-binding protein; Csaids binding protein; CSBP; Csbp1; CSBP2; CSPB1; CT-10 related kinase 3; cytokine suppressive anti-inflammatory drug binding protein; cytokine suppressive anti-inflammatory drug binding protein 1; cytokine suppressive anti-inflammatory drug-binding protein; cytokine-supressive anti-inflammatory drug binding protein; Exip; Hog; I79_016605; MAP kinase 14; MAP kinase 2; MAP kinase Mxi2; MAP kinase p38 alpha; MAPK 14; MAPK14; MAX-interacting protein 2; mitogen activated protein kinase 14; mitogen-activated protein kinase 14; mitogen-activated protein kinase 14A; mitogen-activated protein kinase p38 alpha; MXI2; p38; p38 alpha; p38 MAP kinase; p38 MAP kinase alpha; p38 MAPK; p38 mitogen activated protein kinase; p38a; p38ALPHA; p38-alpha; p38alpha Exip; p38Hog; p38MAPK; PRKM14; PRKM15; Proto-oncogene c-Crk; reactive kinase; RK; SAPK2A; stress-activated protein kinase 2A; tRNA synthetase cofactor p38; v-crk avian sarcoma virus CT10 oncogene homolog; v-crk sarcoma virus CT10 oncogene homolog; v-crk sarcoma virus CT10 oncogene homolog (avian); v-crk sarcoma virus CT10 oncogene-like protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100689104, 100762827, 1398, 1432

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
__

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P46108, Q16539

Gene Symbols:
Crk, Mapk14

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pTyr221 of human CrkII

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Hamster, Human

Product Type:
Antibody

Isotype:
IgG

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PIPA517750

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Antigen:
Phospho-NMDAR1 (Ser890)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GRIN1

Gene Alias:
GluN1; Glun1r; GluRdelta1; Glurz1; GluRzeta1; glutamate [NMDA] receptor subunit zeta 1; glutamate [NMDA] receptor subunit zeta-1; glutamate ionotropic receptor NMDA type subunit 1; glutamate receptor; glutamate receptor ionotropic, NMDA 1; glutamate receptor subunit zeta 1; glutamate receptor, ionotropic, NMDA1 (zeta 1); glutamate receptor, ionotropic, N-methyl D-aspartate 1; GRIN1; M100174; MRD8; neurotransmitter receptor; NMDA R1 receptor C1 cassette; NMDA receptor 1; NMDA1; Nmdar; NMDAR1; NMD-R1; NMDZ1; N-methyl-D-aspartate glutamate receptor; N-methyl-D-aspartate receptor 1; N-methyl-D-aspartate receptor channel, subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1; NMZ1; NR1; NR1C1; NR1C2; NR1C2'; NR1N1; pGluN1; Rgsc174; RP11-350O14.1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14810, 24408, 2902

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
__

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P35438, P35439, Q05586

Gene Symbols:
GRIN1

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding serine 890 of human NMDAR1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA517753

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Antigen:
Phospho-PDGFRB (Tyr751)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Pdgfrb

Gene Alias:
AI528809; Beta platelet-derived growth factor receptor; beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; CD140B; CD140b antigen; IBGC4; IMF1; JTK12; KOGS; PDGF beta chain; PDGF Receptor beta; Pdgfr; Pdgfr1; PDGFR-1; PDGFRB; PDGF-R-beta; PDGFR-beta; PENTT; platelet derived growth factor receptor beta; platelet derived growth factor receptor, beta polypeptide; platelet-derived growth factor receptor 1; Platelet-derived growth factor receptor beta; platelet-derived growth factor receptor beta variant 1; Platelet-derived growth factor receptor, beta; platelet-derived growth factor receptor, beta polypeptide

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18596, 24629, 5159

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Western Blot

Concentration:
14 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P05622, P09619, Q05030

Gene Symbols:
Pdgfrb

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pTyr751 of human PDGF receptor β

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG