PIPA517441

HP1 alpha Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA517441-Each-of-1 In Stock ₹ 44,277.30

PIPA517441 - Each of 1

₹ 44,277.30

In Stock

Quantity

1

Base Price: ₹ 44,277.30

GST (18%): ₹ 7,969.914

Total Price: ₹ 52,247.214

Antigen

HP1 alpha

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Cbx5

Gene Alias

2610029O15Rik; antigen p25; C75991; Cbx5; Cbx5 antibody; chromobox 5; chromobox homolog 5; chromobox homolog 5 (HP1 alpha homolog, Drosophila); chromobox protein homolog 5; chromobox-like protein 5; epididymis luminal protein 25; HEL25; heterochromatin protein 1 alpha; heterochromatin protein 1 homolog alpha; heterochromatin protein 1-alpha; HGNC:1555; HP1; HP1 alpha; HP-1 alpha antibody; HP1 alpha homolog; Hp1a; Hp1alpha; HP1-ALPHA; HP1Hs alpha; HP1Hs-alpha; mHP1(alpha)

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12419, 23468, 300266

Content And Storage

-20°C

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

120 μg/mL

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

P45973, Q61686

Gene Symbols

Cbx5

Immunogen

Synthetic peptide corresponding to the carboxy terminus of human HP1alpha

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • It is not recommended to aliquot this antibody
  • This antibody is not cross-reactive with HP1 beta or HP1 gamma proteins
  • Heterochromatin protein-1 (HP1) is a methyl-lysine binding protein localized at heterochromatin sites, where it mediates gene silencing
  • It has been shown that mammalian methyltransferases that selectively methylate histone H3 on lysine-9 generate a binding site for HP1 proteins, a family of heterochromatic adaptor molecules implicated in both gene silencing and supranucleosomal chromatin structure
  • High-affinity in vitro recognition of a methylated histone H3 peptide by HP1 requires a functional chromodomain
  • Thus, the HP1 chromodomain is a specific interaction motif for the methyl epitope on lysine-9 of histone H3
  • In vivo, heterochromatin association of HP1 proteins is lost in Suv39h double-null primary mouse fibroblasts but is restored after reintroduction of a catalytically active SUV39H1 HMTase.

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Img

Thermo Scientific

PIPA517441

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Antigen:
HP1 alpha

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cbx5

Gene Alias:
2610029O15Rik; antigen p25; C75991; Cbx5; Cbx5 antibody; chromobox 5; chromobox homolog 5; chromobox homolog 5 (HP1 alpha homolog, Drosophila); chromobox protein homolog 5; chromobox-like protein 5; epididymis luminal protein 25; HEL25; heterochromatin protein 1 alpha; heterochromatin protein 1 homolog alpha; heterochromatin protein 1-alpha; HGNC:1555; HP1; HP1 alpha; HP-1 alpha antibody; HP1 alpha homolog; Hp1a; Hp1alpha; HP1-ALPHA; HP1Hs alpha; HP1Hs-alpha; mHP1(alpha)

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12419, 23468, 300266

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
120 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P45973, Q61686

Gene Symbols:
Cbx5

Immunogen:
Synthetic peptide corresponding to the carboxy terminus of human HP1alpha

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA517443

--


Antigen:
Catenin alpha-1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CTNNA1

Gene Alias:
[a]E-catenin; 102 kDa cadherin-associated protein; 2010010M04Rik; AA517462; AI988031; alpha E catenin; alpha E-catenin; alpha(E)-catenin; alpha-E-catenin; cadherin associated protein; Cadherin-associated protein; CAP102; catenin (cadherin associated protein), alpha 1; catenin (cadherin-associated protein), alpha; catenin (cadherin-associated protein), alpha 1; catenin (cadherin-associated protein), alpha 1, 102kDa; catenin alpha 1; catenin alpha 1 S homeolog; catenin alpha-1; catenin, alpha 1; Catna1; cell-adhesion protein alphaE catenin; ctnna; ctnna1; ctnna1.S; MDPT2; Renal carcinoma antigen NY-REN-13; XELAEV_18020018mg

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12385, 1495, 307505

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
9 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P26231, P35221

Gene Symbols:
CTNNA1

Immunogen:
Synthetic peptide corresponding to the carboxy-terminal sequence of human a-E-Catenin

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA517446

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Antigen:
Calcineurin A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PPP3CA

Gene Alias:
2900074D19Rik; Ca2+/calmodulin-regulated protein phosphatase; calcineurin; calcineurin A alpha; Calcineurin A1; calcineurin catalytic subunit; calcineurin catalytic subunit delta isoform; Calcineurin subunit A alpha; CalcineurinA; calmodulin-dependent calcineurin A subunit alpha isoform; caln; CALNA; CALNA 1; CALNA1; CAM-PRP catalytic subunit; CCN 1; ccn1; CN; CnA; CNA alpha; CNA1; PP2B alpha 1; PP2BA alpha; PP2CB; ppp2b; ppp3ca; ppp3ca.S; protein phosphatase; protein phosphatase 2B, catalytic subunit, alpha isoform; protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform; protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha); protein phosphatase 3 catalytic subunit alpha; protein phosphatase 3 catalytic subunit alpha isozyme; protein phosphatase 3, catalytic subunit, alpha isoform; protein phosphatase 3, catalytic subunit, alpha isozyme; protein phosphatase 3, catalytic subunit, alpha isozyme S homeolog; protein phosphatase 3, catalytic subunit, gamma isozyme; protein phosphatase-2Ba; serine/threonine protein kinase; serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform; XELAEV_18009418mg

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19055, 24674, 5530

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration:
10 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P63328, P63329, Q08209

Gene Symbols:
PPP3CA

Immunogen:
Synthetic peptide corresponding to the carboxy-terminus of human Calcineurin A (alpha isoform)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA517447

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Antigen:
Caveolin 1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CAV1

Gene Alias:
BSCL3; CAV; CAV1; Cav-1; caveolae; caveolin 1; caveolin 1, caveolae protein; caveolin 1, caveolae protein, 22kDa; caveolin 1a; caveolin 1b; caveolin caveolae protein 22 kDa; caveolin, caveolae protein 1; caveolin, caveolae protein, 22 kDa; caveolin-1; caveolin-1a; caveolin-1b; cell growth-inhibiting protein 32; CGL3; HGNC:1527; LCCNS; MSTP085; OTTHUMP00000196475; PPH3; Unknown (protein for IMAGE:7985573); variant a; variant b; vesicular integral-membrane protein VIP21; VIP21; wu:fc07c04

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100753021, 12389, 25404, 281040, 323695, 373996, 404693, 857

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
33 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P35431, P41350, P49817, P79132, Q03135, Q6RVA9

Gene Symbols:
CAV1

Immunogen:
Synthetic peptide corresponding to residues surrounding Glu20 of human caveolin-1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Chicken, Hamster, Human, Mouse, Porcine, Rat, Zebrafish

Product Type:
Antibody

Isotype:
IgG