PIPA517818

Phospho-CHK2 (Thr68) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA517818-Each-of-1 In Stock ₹ 51,164.88

PIPA517818 - Each of 1

₹ 51,164.88

In Stock

Quantity

1

Base Price: ₹ 51,164.88

GST (18%): ₹ 9,209.678

Total Price: ₹ 60,374.558

Antigen

Phospho-CHK2 (Thr68)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Chek2

Gene Alias

CDS1; cds1 homolog; Checkpoint kinase 2; Checkpoint like protein CHK2; checkpoint-like protein CHK2; Chek2; Chk2; Chk2 (phospho T68); Chk2 (pThr68); CHK2 checkpoint homolog; CHK2 checkpoint homolog (S. pombe); Chk2 phospho; Chk2 phospho T68; del9; EC 2.7.11.1; hCds1; HuCds 1; HuCds1; kinase Chk2; LFS2; OTTHUMP00000199044; OTTHUMP00000199045; OTTHUMP00000199064; OTTHUMP00000199115; OTTHUMP00000199116; phospho Chk2 (T68); phospho Thr68 Chk2; PP1425; protein kinase Chk2; Rad53; Rad53 homolog; RP11-436C9.1; Serine/threonine protein kinase Chk2; serine/threonine-protein kinase Chk2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11200

Content And Storage

-20°C

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration

99 μg/mL

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

O96017

Gene Symbols

Chek2

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding pThr68 of human Chk2

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Non-human Primate

Product Type

Antibody

Isotype

IgG

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Description

  • It is not recommended to aliquot this antibody
  • This antibody is not cross-reactive with Chk2 phosphorylated at other sites
  • This antibody was orginally validated as part of a Thermo Scientific Cellomics High Content Screening Kit
  • The antibody sold separately may have slightly different performance and may need to be further optimized for the best results
  • CHEK2 (CHK2) is a serine/threonine kinase and a component of the DNA damage checkpoint pathway
  • A mutation in CHK2 has been linked to cancer
  • CHK2 is activated by DNA damage and phosphorylates several modulators of cell cycle control including tumor suppressor proteins
  • In addition, Chk2 can phosphorylate BRCA1, allowing BRCA1 to restore survival after DNA damage
  • Chk2 is a putative tumor suppressor protein, with mutations in to the Chk2 gene linked to Li-Fraumeni syndrome, a familiar cancer usually associated with inherited mutations in TP53
  • Also, mutations in CHK2 are thought to confer a predisposition to sarcomas, breast cancer, and brain tumors.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA517818

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Antigen:
Phospho-CHK2 (Thr68)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Chek2

Gene Alias:
CDS1; cds1 homolog; Checkpoint kinase 2; Checkpoint like protein CHK2; checkpoint-like protein CHK2; Chek2; Chk2; Chk2 (phospho T68); Chk2 (pThr68); CHK2 checkpoint homolog; CHK2 checkpoint homolog (S. pombe); Chk2 phospho; Chk2 phospho T68; del9; EC 2.7.11.1; hCds1; HuCds 1; HuCds1; kinase Chk2; LFS2; OTTHUMP00000199044; OTTHUMP00000199045; OTTHUMP00000199064; OTTHUMP00000199115; OTTHUMP00000199116; phospho Chk2 (T68); phospho Thr68 Chk2; PP1425; protein kinase Chk2; Rad53; Rad53 homolog; RP11-436C9.1; Serine/threonine protein kinase Chk2; serine/threonine-protein kinase Chk2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11200

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration:
99 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
O96017

Gene Symbols:
Chek2

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pThr68 of human Chk2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG

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PIPA517820

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Antigen:
alpha Synuclein

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SNCA

Gene Alias:
Alpha synuclein; alphaSYN; alpha-synuclein; NACP; non A-beta component of AD amyloid; non-A beta component of AD amyloid; non-A4 component of amyloid; Non-A4 component of amyloid precursor; PARK1; PARK4; PD1; Snca; Syn; synuclein alpha; synuclein alpha-140; synuclein, alpha; synuclein, alpha (non A4 component of amyloid precursor)

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20617, 29219, 6622

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration:
60 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
O55042, P37377, P37840

Gene Symbols:
SNCA

Immunogen:
Synthetic peptide corresponding to the carboxy-terminal sequence of human a-synuclein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA517823

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Antigen:
Phospho-PRK1/PRK2 (Thr774, Thr816)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PKN2

Gene Alias:
6030436C20Rik; AI507382; cardiolipin-activated protein kinase Pak2; DBK; F730027O18Rik; p140 kinase; PAK1; PAK-1; PAK2; Pak-2; Pkn; PKN gamma; Pkn1; Pkn2; PKN-ALPHA; Prk1; Prk2; Prkcl1; PRKCL2; PRO2042; protease-activated kinase 1; protease-activated kinase 2; protein kinase C-like 1; Protein kinase C-like 2; protein kinase C-like PKN; protein kinase C-related kinase 1; protein kinase N1; protein kinase N2; protein kinase PKN; protein kinase PKN-alpha; Protein-kinase C-related kinase 1; protein-kinase C-related kinase 2; serine/threonine kinase 3; serine/threonine kinase 7; serine/threonine protein kinase N; serine/threonine-protein kinase N1; Serine/threonine-protein kinase N2; serine-threonine kinase N; serine-threonine protein kinase N; Stk3; Stk7

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
109333, 207122, 29355, 320795, 5585, 5586

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
__

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
O08874, P70268, Q16512, Q16513, Q63433, Q8BWW9

Gene Symbols:
PKN1, PKN2

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pThr774 of human PRK1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA517824

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Antigen:
Phospho-eIF4G (Ser1108)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EIF4G1

Gene Alias:
DKFZp686A1451; E030015G23Rik; EIF4F; EIF4G; eIF-4G 1; EIF4G1; eIF-4G1; EIF4-gamma; eIF-4-gamma 1; EIF4GI; eIF4GI protein; eucaryotic translation initiation factor 4G; Eukaryotic translation initiation factor 4 gamma 1; eukaryotic translation initiation factor 4 gamma, 1; eukaryotic translation initiation factor 4, gamma 1; OTTHUMP00000210577; OTTHUMP00000210586; OTTHUMP00000210587; OTTHUMP00000210588; OTTHUMP00000210595; OTTHUMP00000210602; OTTHUMP00000210603; P220; PARK18

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100770567, 1981, 208643, 287986, 444858

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration:
142 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
Q04637, Q6NZJ6

Gene Symbols:
EIF4G1

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pSer1108 of human eIF4GI

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Hamster, Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG