PIPA518580

SBP2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA518580-Each-of-1 In Stock ₹ 44,705.10

PIPA518580 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

SBP2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SECISBP2

Gene Alias

2210413N07Rik; 2810012K13Rik; DKFZp686C09169; OTTHUMP00000064929; OTTHUMP00000064930; OTTHUMP00000064931; OTTHUMP00000064932; RP11-89K14.1; Sbp2; SECIS binding protein 2; SECIS-binding protein 2; SECISBP2; Selenocysteine insertion sequence-binding protein 2

Host Species

Goat

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

75420, 79048

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

0.5 mg/mL

Formulation

TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q96T21

Gene Symbols

SECISBP2

Immunogen

Synthetic peptide sequence (KERQERKQRLQEN) corresponding to the internal amino acids of SECISBP2

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is predicted to react with bovine, canine and porcine based on sequence homology
  • This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000
  • Eukaryotes require a selenocysteine (Sec) insertion sequence (SECIS) element in the 3' untranslated region of the mRNA to decode the UGA codon as Sec
  • SECIS-binding protein 2 (SBP-2) specifically binds selenoprotein mRNAs to form a functional complex and is essential for the insertion of Sec into selenoproteins
  • Purified SBP-2 interacts specifically with the SECIS element in the phospholipid hydroperoxide glutathione peroxidase mRNA
  • SBP-2 shows binding activity in the liver and testis as well as hepatoma cells
  • SBP-2 binds to a conserved RNA binding domain shared with several ribosomal proteins and eukaryotic translation termination release factor 1
  • A second domain located N-terminal to the RNA binding domain required for Sec insertion allows SBP-2 to stably associate with the ribosomal fraction of cells
  • SBP-2 preferentially stimulates incorporation directed by the selenoprotein P and phospholipid hydroperoxide glutathione peroxidase SECIS elements
  • SBP-2 may have a distinct function in selecting the ribosomes for Sec insertion.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA518580

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Antigen:
SBP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SECISBP2

Gene Alias:
2210413N07Rik; 2810012K13Rik; DKFZp686C09169; OTTHUMP00000064929; OTTHUMP00000064930; OTTHUMP00000064931; OTTHUMP00000064932; RP11-89K14.1; Sbp2; SECIS binding protein 2; SECIS-binding protein 2; SECISBP2; Selenocysteine insertion sequence-binding protein 2

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
75420, 79048

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q96T21

Gene Symbols:
SECISBP2

Immunogen:
Synthetic peptide sequence (KERQERKQRLQEN) corresponding to the internal amino acids of SECISBP2

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA518581

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Antigen:
SV2A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SV2A

Gene Alias:
AI746429; calcium regulator SV2A; Kiaa0736; mKIAA0736; PSEC0174; SV2; SV2A; synaptic vesicle glycoprotein 2 a; synaptic vesicle glycoprotein 2a; Synaptic vesicle protein 2; synaptic vesicle protein 2A; synaptic vesicle transmembrane transporter (SV2) RNA

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
117559, 9900

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q02563, Q7L0J3

Gene Symbols:
SV2A

Immunogen:
Synthetic peptide sequence (TVELYPSDKRTTA) corresponding to the internal amino acids of SV2A

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA518582

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Antigen:
FLAP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ALOX5AP

Gene Alias:
5-lipoxygenase-activating protein FLAP; Alox5ap; arachidonate 5-lipoxygenase activating protein; arachidonate 5-lipoxygenase-activating protein; Flap; MK-886-binding protein

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
241

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P20292

Gene Symbols:
ALOX5AP

Immunogen:
Synthetic peptide sequence (HKVEHESRTQNGR) corresponding to the internal amino acids of ALOX5AP

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA518584

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Antigen:
XLF

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NHEJ1

Gene Alias:
1700029B21Rik; cernunnos; FLJ12610; Nhej1; non-homologous end joining factor 1; non-homologous end-joining factor 1; nonhomologous end-joining factor 1; protein cernunnos; Xlf; XRCC4-like factor

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
79840

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9H9Q4

Gene Symbols:
NHEJ1

Immunogen:
Synthetic peptide sequence (QRPQLSKVKRKKPR) corresponding to the C-terminus amino acids of NHEJ1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG