PIPA518940

XBP1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA518940-Each-of-1 In Stock ₹ 47,015.22

PIPA518940 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

XBP1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Xbp1

Gene Alias

D11Ertd39e; Hepatocarcinogenesis-related transcription factor; HTF; OTTHUMP00000028682; Tax-responsive element-binding protein 5; tax-responsive element-binding protein 5 homolog; TREB5; TREB-5; X-box binding protein 1; X-box-binding protein 1; X-box-binding protein 1, cytoplasmic form; X-box-binding protein 1, luminal form; XBP1; XBP-1; XBP2

Host Species

Goat

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

7494

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration

0.5 mg/mL

Formulation

TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.

P17861

Gene Symbols

Xbp1

Immunogen

Synthetic peptide sequence (NHSWEDTFANELFPQ) corresponding to the internal amino acids of XBP1

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is predicted to react with canine based on sequence homology
  • This antibody is tested in Peptide ELISA: antibody detection limit dilution 4,000
  • XBP1 encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box
  • This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter
  • It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator
  • It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1)
  • The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1(S), which is the functionally active transcription factor
  • The isoform encoded by the unspliced mRNA, XBP1(U), is constitutively expressed, and thought to function as a negative feedback regulator of XBP1(S), which shuts off transcription of target genes during the recovery phase of ER stress
  • A pseudogene of XBP1 has been identified and localized to chromosome 5.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA518940

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Antigen:
XBP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Xbp1

Gene Alias:
D11Ertd39e; Hepatocarcinogenesis-related transcription factor; HTF; OTTHUMP00000028682; Tax-responsive element-binding protein 5; tax-responsive element-binding protein 5 homolog; TREB5; TREB-5; X-box binding protein 1; X-box-binding protein 1; X-box-binding protein 1, cytoplasmic form; X-box-binding protein 1, luminal form; XBP1; XBP-1; XBP2

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
7494

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P17861

Gene Symbols:
Xbp1

Immunogen:
Synthetic peptide sequence (NHSWEDTFANELFPQ) corresponding to the internal amino acids of XBP1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA518942

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Antigen:
FTO

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Fto

Gene Alias:
AlkB homolog 9; ALKBH9; alpha-ketoglutarate-dependent dioxygenase FTO; AW743446; BMIQ14; fat mass and obesity associated; fat mass and obesity-associated protein; fatso; FTO; GDFD; KIAA1752; m6A(m)-demethylase FTO; MGC5149; mKIAA1752; mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; mRNA N(6)-methyladenosine demethylase FTO; Protein fatso; protein fto; RGD1305121; tRNA N1-methyl adenine demethylase FTO; U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
79068

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9C0B1

Gene Symbols:
Fto

Immunogen:
Synthetic peptide sequence (QQKPDCRPYWEKDD) corresponding to the internal amino acids of Fto

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA518943

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Antigen:
SEL1L

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SEL1L

Gene Alias:
AW493766; fj60e07; IBD2; mKIAA4137; PRO1063; Protein sel-1 homolog 1; Sel1 (suppressor of lin-12) 1 homolog; sel-1 suppressor of lin-12-like; sel-1 suppressor of lin-12-like (C. elegans); sel-1 suppressor of lin-12-like 1; Sel1h; SEL1L; sel-1L; SEL1L adaptor subunit of ERAD E3 ubiquitin ligase; SEL1L ERAD E3 ligase adaptor subunit; SEL1L, ERAD E3 ligase adaptor subunit; SEL1L1; SEL1-LIKE; si:dkey-177p2.3; Suppressor of lin 12 (sel-1), C. elegans, homolog of; suppressor of lin-12-like protein 1; TSA305; UNQ128/PRO1063; wu:fj60e07; zgc:56075

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
6400

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9UBV2

Gene Symbols:
SEL1L

Immunogen:
Synthetic peptide sequence (TAYNSYKDGDYN) corresponding to the internal amino acids of SEL1L

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA518945

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Antigen:
LHX2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Lhx2

Gene Alias:
ap; apterous; hLhx2; Homeobox protein LH-2; LH2; Lh-2; LH2A; LHX2; LIM homeo box protein 2; LIM homeobox 2; LIM homeobox protein 2; LIM HOX gene 2; LIM/homeobox protein Lhx2; Lim2; MGC138390

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
9355

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P50458

Gene Symbols:
Lhx2

Immunogen:
Synthetic peptide sequence (NLEGHEPHSPSQ) corresponding to the C-terminus amino acids of LHX2

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG