PIPA519872
ADAM17 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA519872-Each-of-1 | In Stock | ₹ 47,271.90 |
PIPA519872 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,271.90
GST (18%): ₹ 8,508.942
Total Price: ₹ 55,780.842
Antigen
ADAM17
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ADAM17
Gene Alias
a disintegrin and metallopeptidase domain 17; a disintegrin and metalloprotease domain 17; a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 17; a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme); ADAM; ADAM 17; ADAM metallopeptidase domain 17; ADAM metallopeptidase domain 18; Adam17; ADAM18; ADAMs; CD156B; CD156b antigen; CSVP; Disintegrin and metalloproteinase domain-containing protein 17; metalloendopeptidases; NISBD; NISBD1; Snake venom-like protease; TACE; TNF-alpha convertase; TNF-alpha converting enzyme; TNF-alpha-converting enzyme; tumor necrosis factor, alpha, converting enzyme
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
57027, 6868
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
P78536, Q9Z1K9
Gene Symbols
ADAM17
Immunogen
A 17 amino acid peptide near the carboxy terminus of human TACE
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A suggested positive control is Hela cell lysate
- A 17 amino acid peptide near the carboxy terminus of human TACE
- The PA5-19872 immunogen is located within the last 50 amino acids of TACE
- Predicted molecular ∽ 93kD
- In Western blot applications, this antibody has been observed to detect a band at: 93-125kD (Post-modification: 9 N-linked glycosylation)
- Predicted species reactivity based on immunogen sequence: mouse (94.1%)
- ADAM17 (disintegrin and metalloproteinase domain-containing protein 17) cleaves the membrane bound precusor of TNF-alpha to its mature soluble form
- ADAM 17 is responsbile for the proteolytical release of soluble JAM3 from endothelial cells surface and the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1, and the amyloid precursor protein
- It acts as an activator of the Notch pathway by mediating cleavage of Notch and generating the membrane-associated intermediate fragment called Notch extracellular truncation (NEXT)
- Mutations in the gene can result in inflammatory skin and bowel disease, neonatal 1.
Compare Similar Items
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Antigen: ADAM17
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ADAM17
Gene Alias: a disintegrin and metallopeptidase domain 17; a disintegrin and metalloprotease domain 17; a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 17; a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme); ADAM; ADAM 17; ADAM metallopeptidase domain 17; ADAM metallopeptidase domain 18; Adam17; ADAM18; ADAMs; CD156B; CD156b antigen; CSVP; Disintegrin and metalloproteinase domain-containing protein 17; metalloendopeptidases; NISBD; NISBD1; Snake venom-like protease; TACE; TNF-alpha convertase; TNF-alpha converting enzyme; TNF-alpha-converting enzyme; tumor necrosis factor, alpha, converting enzyme
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 57027, 6868
Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: P78536, Q9Z1K9
Gene Symbols: ADAM17
Immunogen: A 17 amino acid peptide near the carboxy terminus of human TACE
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ADAM17
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ADAM17
Gene Alias:
a disintegrin and metallopeptidase domain 17; a disintegrin and metalloprotease domain 17; a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 17; a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme); ADAM; ADAM 17; ADAM metallopeptidase domain 17; ADAM metallopeptidase domain 18; Adam17; ADAM18; ADAMs; CD156B; CD156b antigen; CSVP; Disintegrin and metalloproteinase domain-containing protein 17; metalloendopeptidases; NISBD; NISBD1; Snake venom-like protease; TACE; TNF-alpha convertase; TNF-alpha converting enzyme; TNF-alpha-converting enzyme; tumor necrosis factor, alpha, converting enzyme
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
57027, 6868
Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
P78536, Q9Z1K9
Gene Symbols:
ADAM17
Immunogen:
A 17 amino acid peptide near the carboxy terminus of human TACE
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: GFR alpha-3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Gfra3
Gene Alias: GDNF family receptor alpha 3; GDNF family receptor alpha-3; GDNF receptor alpha-3; GDNF-family receptor alpha 3; GDNFR3; GDNFR-alpha-3; GFR alpha-3; GFRA3; GFRalpha3; GFR-alpha-3; glial cell line derived neurotrophic factor family receptor alpha 3; glial cell line-derived neurotrophic factor receptor alpha-3; GPI-linked receptor; UNQ339/PRO538/PRO3664; Y15110
Host Species: Rabbit
Purification Method: Ion-exchange chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14587, 2676, 84422
Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: O35118, O60609
Gene Symbols: Gfra3
Immunogen: A peptide corresponding to amino acids from 347 to 360 of murine GFR alpha 3.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
GFR alpha-3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Gfra3
Gene Alias:
GDNF family receptor alpha 3; GDNF family receptor alpha-3; GDNF receptor alpha-3; GDNF-family receptor alpha 3; GDNFR3; GDNFR-alpha-3; GFR alpha-3; GFRA3; GFRalpha3; GFR-alpha-3; glial cell line derived neurotrophic factor family receptor alpha 3; glial cell line-derived neurotrophic factor receptor alpha-3; GPI-linked receptor; UNQ339/PRO538/PRO3664; Y15110
Host Species:
Rabbit
Purification Method:
Ion-exchange chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14587, 2676, 84422
Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
O35118, O60609
Gene Symbols:
Gfra3
Immunogen:
A peptide corresponding to amino acids from 347 to 360 of murine GFR alpha 3.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: FLIP
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CFLAR
Gene Alias: 2310024N18Rik; A430105C05Rik; Cash; CASP8 and FADD like apoptosis regulator; CASP8 and FADD-like apoptosis regulator; CASP8 and FADD-like apoptosis regulator subunit p12; CASP8 and FADD-like apoptosis regulator subunit p43; CASP8AP1; caspase homolog; Caspase-eight-related protein; caspase-like apoptosis regulatory protein; caspase-related inducer of apoptosis; Casper; Cellular FLICE-like inhibitory protein; Cflar; c-Flip; c-FLIPL; c-FLIPR; c-FLIPS; CLARP; ENSMUSG00000072980; FADD-like antiapoptotic molecule 1; FLAME; FLAME1; FLAME-1; Flip; Gm9845; I-FLICE; Inhibitor of FLICE; MACH-related inducer of toxicity; MRIT; testis secretory sperm-binding protein Li 233m; usurpin; usurpin beta
Host Species: Rabbit
Purification Method: Ion-exchange chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12633
Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: O35732
Gene Symbols: CFLAR
Immunogen: A peptide corresponding to amino acids 449 to 465 of mouse FLIPL/CASHa.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
FLIP
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CFLAR
Gene Alias:
2310024N18Rik; A430105C05Rik; Cash; CASP8 and FADD like apoptosis regulator; CASP8 and FADD-like apoptosis regulator; CASP8 and FADD-like apoptosis regulator subunit p12; CASP8 and FADD-like apoptosis regulator subunit p43; CASP8AP1; caspase homolog; Caspase-eight-related protein; caspase-like apoptosis regulatory protein; caspase-related inducer of apoptosis; Casper; Cellular FLICE-like inhibitory protein; Cflar; c-Flip; c-FLIPL; c-FLIPR; c-FLIPS; CLARP; ENSMUSG00000072980; FADD-like antiapoptotic molecule 1; FLAME; FLAME1; FLAME-1; Flip; Gm9845; I-FLICE; Inhibitor of FLICE; MACH-related inducer of toxicity; MRIT; testis secretory sperm-binding protein Li 233m; usurpin; usurpin beta
Host Species:
Rabbit
Purification Method:
Ion-exchange chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12633
Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
O35732
Gene Symbols:
CFLAR
Immunogen:
A peptide corresponding to amino acids 449 to 465 of mouse FLIPL/CASHa.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: DR3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TNFRSF25
Gene Alias: APO3; APO-3; apoptosis inducing receptor; apoptosis-inducing receptor AIR; Apoptosis-mediating receptor DR3; apoptosis-mediating receptor TRAMP; DDR3; death domain receptor 3 soluble form; Death receptor 3; death receptor beta; DR3; LARD; lymphocyte-associated receptor of death; Protein WSL; Protein WSL-1; RP4-650H14.2; TNF receptor superfamily member 25; TNFRSF12; TNFRSF25; TR3; TRAMP; tumor necrosis factor receptor superfamily member 25; tumor necrosis factor receptor superfamily, member 12; tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein); tumor necrosis factor receptor superfamily, member 25; UNQ455/PRO779; Wsl; WSL1; WSL-1; WSL-LR
Host Species: Rabbit
Purification Method: Ion-exchange chromatography
Regulatory Status: RUO
Gene ID (Entrez): 85030, 8718
Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: Q93038
Gene Symbols: TNFRSF25
Immunogen: A peptide corresponding to amino acids 25 to 40 of human DR3 precusor.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
DR3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TNFRSF25
Gene Alias:
APO3; APO-3; apoptosis inducing receptor; apoptosis-inducing receptor AIR; Apoptosis-mediating receptor DR3; apoptosis-mediating receptor TRAMP; DDR3; death domain receptor 3 soluble form; Death receptor 3; death receptor beta; DR3; LARD; lymphocyte-associated receptor of death; Protein WSL; Protein WSL-1; RP4-650H14.2; TNF receptor superfamily member 25; TNFRSF12; TNFRSF25; TR3; TRAMP; tumor necrosis factor receptor superfamily member 25; tumor necrosis factor receptor superfamily, member 12; tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein); tumor necrosis factor receptor superfamily, member 25; UNQ455/PRO779; Wsl; WSL1; WSL-1; WSL-LR
Host Species:
Rabbit
Purification Method:
Ion-exchange chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
85030, 8718
Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
Q93038
Gene Symbols:
TNFRSF25
Immunogen:
A peptide corresponding to amino acids 25 to 40 of human DR3 precusor.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG