PIPA519886

DR3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA519886-Each-of-1 In Stock ₹ 44,705.10

PIPA519886 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

DR3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TNFRSF25

Gene Alias

APO3; APO-3; apoptosis inducing receptor; apoptosis-inducing receptor AIR; Apoptosis-mediating receptor DR3; apoptosis-mediating receptor TRAMP; DDR3; death domain receptor 3 soluble form; Death receptor 3; death receptor beta; DR3; LARD; lymphocyte-associated receptor of death; Protein WSL; Protein WSL-1; RP4-650H14.2; TNF receptor superfamily member 25; TNFRSF12; TNFRSF25; TR3; TRAMP; tumor necrosis factor receptor superfamily member 25; tumor necrosis factor receptor superfamily, member 12; tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein); tumor necrosis factor receptor superfamily, member 25; UNQ455/PRO779; Wsl; WSL1; WSL-1; WSL-LR

Host Species

Rabbit

Purification Method

Ion-exchange chromatography

Regulatory Status

RUO

Gene ID (Entrez)

85030, 8718

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q93038

Gene Symbols

TNFRSF25

Immunogen

A peptide corresponding to amino acids 25 to 40 of human DR3 precusor.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • In Western blot applications, this antibody detects a band at ∽59kDa
  • A suggested positive control is Jurkat cell lysate
  • PA5-19886 can be used with blocking peptide PEP-0015
  • DR3/TNFRSF25 is a member of the TNF-receptor superfamily
  • This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis
  • This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis
  • The signal transduction of this receptor is mediated by various death domain containing adaptor proteins
  • Knockout studies in mice suggested the role of DR3/TNFRSF25 in the removal of self-reactive T cells in the thymus
  • Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules
  • The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA519886

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Antigen:
DR3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TNFRSF25

Gene Alias:
APO3; APO-3; apoptosis inducing receptor; apoptosis-inducing receptor AIR; Apoptosis-mediating receptor DR3; apoptosis-mediating receptor TRAMP; DDR3; death domain receptor 3 soluble form; Death receptor 3; death receptor beta; DR3; LARD; lymphocyte-associated receptor of death; Protein WSL; Protein WSL-1; RP4-650H14.2; TNF receptor superfamily member 25; TNFRSF12; TNFRSF25; TR3; TRAMP; tumor necrosis factor receptor superfamily member 25; tumor necrosis factor receptor superfamily, member 12; tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein); tumor necrosis factor receptor superfamily, member 25; UNQ455/PRO779; Wsl; WSL1; WSL-1; WSL-LR

Host Species:
Rabbit

Purification Method:
Ion-exchange chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
85030, 8718

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q93038

Gene Symbols:
TNFRSF25

Immunogen:
A peptide corresponding to amino acids 25 to 40 of human DR3 precusor.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA519887

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Antigen:
DR4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TNFRSF10A

Gene Alias:
APO2; CD261; cytotoxic TRAIL receptor; death receptor 4; DR4; MGC9365; sCD261; soluble CD261; soluble TRAIL; sTRAIL; TNF receptor superfamily member 10a; TNF-related apoptosis-inducing ligand receptor 1; TNFRSF10A; TRAIL R1; TRAIL receptor 1; TRAILR1; TRAIL-R1; TRAILR-1; tumor necrosis factor receptor superfamily member 10A; tumor necrosis factor receptor superfamily member 10a variant 2; tumor necrosis factor receptor superfamily, member 10a

Host Species:
Rabbit

Purification Method:
Ion-exchange chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8797

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O00220

Gene Symbols:
TNFRSF10A

Immunogen:
A 20 amino acid peptide near the amino terminus of human DR4

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA519888

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Antigen:
CXCR6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CXCR6

Gene Alias:
BB217514; BONZO; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; CD186; CD186 antigen; CDw186; chemokine (C-X-C motif) receptor 6; chemokine receptor CXCR6; CXC; C-X-C chemokine receptor type 6; CXC motif chemokine; C-X-C motif chemokine receptor 6; Cxcr6; CXC-R6; CXCR-6; G protein-coupled receptor; G-protein coupled receptor bonzo; G-protein coupled receptor STRL33; OTTHUMP00000209997; OTTHUMP00000209998; STRL33; TYMSTR

Host Species:
Rabbit

Purification Method:
Ion-exchange chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10663

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O00574

Gene Symbols:
CXCR6

Immunogen:
A peptide corresponding to amino acids 319 to 338 of human BONZO

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA519889

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Antigen:
ICAD

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DFFA

Gene Alias:
A330085O09Rik; DFF; DFF1; DFF35; Dff45; DFF-45; Dffa; DNA fragmentation factor 45 kDa subunit; DNA fragmentation factor subunit alpha; DNA fragmentation factor, 45kDa, alpha polypeptide; DNA fragmentation factor, alpha subunit; H13; ICAD; ICAD-L; ICAD-S; Inhibitor of CAD; RP23-121D17.3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13347

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O54786

Gene Symbols:
DFFA

Immunogen:
A peptide corresponding to amino acids near the amino terminus of mouse ICAD.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG