PIPA520132

TSC2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA520132-Each-of-1 In Stock ₹ 44,705.10

PIPA520132 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

TSC2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TSC2

Gene Alias

LAM; Nafld; OTTHUMP00000198394; PPP1R160; protein phosphatase 1, regulatory subunit 160; Rc; renal carcinoma; Tcs2; Tsc2; TSC4; Tuberin; tuberous sclerosis 2; tuberous sclerosis 2 homolog protein; tuberous sclerosis 2 protein; Tuberous sclerosis 2 protein homolog

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

22084, 7249

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

P49815, Q61037

Gene Symbols

TSC2

Immunogen

A 15 amino acid peptide from near the carboxy terminus of human TSC2.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • A suggested positive control is L1210 cell lysate
  • PA5-20132 can be used with blocking peptide PEP-0250
  • TSC2 (Tuberin, Tuberous sclerosis complex, TSC Complex Subunit 2), is implicated as a tumor suppressor and may function in vesicular transport, play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors
  • TSC2 associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin
  • Phosphorylation of tuberin on Ser 939 and Thr 1462 regulates its interaction with hamartin, and is stimulated by various growth factors through the phosphoinositide 3-kinase/Akt pathway
  • TSC2 may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors
  • Interaction between TSC1 and TSC2 may facilitate vesicular docking
  • TSC2 specifically stimulates the intrinsic GTPase activity of the Ras related protein RAP1A and RAB5, suggesting a possible mechanism for its role in regulating cellular growth
  • Mutations in TSC2 lead to constitutive activation of RAP1A in tumors and are involved in diseases such as lymphangioleiomyomatosis and TSC2 angiomyolipoma
  • Alternative splicing results in transcript variants of three different isoforms of TSC2.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA520132

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Antigen:
TSC2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TSC2

Gene Alias:
LAM; Nafld; OTTHUMP00000198394; PPP1R160; protein phosphatase 1, regulatory subunit 160; Rc; renal carcinoma; Tcs2; Tsc2; TSC4; Tuberin; tuberous sclerosis 2; tuberous sclerosis 2 homolog protein; tuberous sclerosis 2 protein; Tuberous sclerosis 2 protein homolog

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22084, 7249

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P49815, Q61037

Gene Symbols:
TSC2

Immunogen:
A 15 amino acid peptide from near the carboxy terminus of human TSC2.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA520135

--


Antigen:
4EBP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EIF4EBP1

Gene Alias:
4EBP1; 4E-BP1; AA959816; BP-1; eIF4E-binding protein 1; EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; MGC431; MGC4316; P/OKCL.6; PHAS-1; PHAS-I; Phosphorylated heat- and acid-stable protein regulated by insulin 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13685, 1978

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q13541, Q60876

Gene Symbols:
EIF4EBP1

Immunogen:
A 14 amino acid peptide from near the carboxy terminus of human 4E-BP1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520137

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Antigen:
IRS1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IRS1

Gene Alias:
G972R; HIRS-1; Insulin receptor substrate 1; IRS1; IRS-1; IRS1IRM; pp185

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16367, 3667

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P35568, P35569

Gene Symbols:
IRS1

Immunogen:
A 16 amino acid peptide from near the center of human IRS-1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA520146

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Antigen:
CTRP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
C1QTNF1

Gene Alias:
1600017K21Rik; C1q and tumor necrosis factor related protein 1; C1qtnf1; Complement C1q tumor necrosis factor-related protein 1; Ctrp1; G protein coupled receptor interacting protein; g protein-coupled receptor-interacting protein; GIP; putative secreted protein ZSIG37; UNQ310/PRO353; Zsig37

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
114897, 303701, 56745

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q5XIG2, Q9BXJ1, Q9QXP7

Gene Symbols:
C1QTNF1

Immunogen:
A 15 amino acid peptide from near the amino-terminus of human CTRP1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG