PIPA520343

PD-L1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA520343-Each-of-1 In Stock ₹ 48,897.54

PIPA520343 - Each of 1

₹ 48,897.54

In Stock

Quantity

1

Base Price: ₹ 48,897.54

GST (18%): ₹ 8,801.557

Total Price: ₹ 57,699.097

Antigen

PD-L1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Cd274

Gene Alias

A530045L16Rik; B7 homolog 1; B7-H; B7h1; B7-H1; Cd274; CD274 antigen; CD274 molecule; PDCD1 ligand 1; Pdcd1l1; Pdcd1lg1; Pdl1; PD-L1; pdl-1; Programmed cell death 1 ligand 1; programmed death ligand 1; RGD1566211; sCD274; soluble CD274; soluble PD L1; sPD L1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

29126, 499342, 60533

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

Q9EP73, Q9NZQ7

Gene Symbols

Cd274

Immunogen

A 17 amino acid peptide from near the center of human PDL-1.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • This antibody detects human PD-L1 isoform 1 (290aa, 33.3 kDa) and isoform 3 (178aa, 20.5 kDa), as well as mouse and rat PD-L1 (290aa, 33 kDa)
  • It will not cross-react with PD-L2
  • By Western blot, this antibody has been observed to detect a band at 37 kDa
  • Recommended positive controls: HeLa cell lysate, Daudi cell lysate, K562 cell lysate, human heart tissue/lysate
  • PA5-20343 can be used with blocking peptide PEP-0463
  • The PA5-20343 immunogen is located within amino acids 60-110 of PD-L1
  • Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a recently described B7 family member
  • To date, one specific receptor has been identified that can be ligated by PD-L1
  • This receptor, programmed death receptor 1 (PD-1), has been shown to negatively regulate T-cell receptor (TCR) signaling
  • Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production
  • PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation
  • Thus, PD-L1 might play an important role in tumor immune evasion.

Compare Similar Items

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Img

Thermo Scientific

PIPA520343

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Antigen:
PD-L1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cd274

Gene Alias:
A530045L16Rik; B7 homolog 1; B7-H; B7h1; B7-H1; Cd274; CD274 antigen; CD274 molecule; PDCD1 ligand 1; Pdcd1l1; Pdcd1lg1; Pdl1; PD-L1; pdl-1; Programmed cell death 1 ligand 1; programmed death ligand 1; RGD1566211; sCD274; soluble CD274; soluble PD L1; sPD L1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
29126, 499342, 60533

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q9EP73, Q9NZQ7

Gene Symbols:
Cd274

Immunogen:
A 17 amino acid peptide from near the center of human PDL-1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520345

--


Antigen:
SCO1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SCO1

Gene Alias:
2610001C07Rik; D11Bwg1310e; Protein SCO1 homolog, mitochondrial; RGD1559538; SCO cytochrome c oxidase assembly protein 1; SCO cytochrome oxidase deficient homolog 1; SCO cytochrome oxidase deficient homolog 1 (yeast); SCO1; SCO1 cytochrome c oxidase assembly protein; SCO1, cytochrome c oxidase assembly protein; SCOD1; synthesis of cytochrome C oxidase 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
497930, 52892, 6341

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O75880, Q5SUC9

Gene Symbols:
SCO1

Immunogen:
A 14 amino acid peptide from near the center of human SCO1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520347

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Antigen:
TIGAR

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TIGAR

Gene Alias:
9630033F20Rik; AA793651; AI595337; C12orf5; C27H12orf5; C79710; C85509; FR2BP; Fructose-2,6-bisphosphatase TIGAR; fructose-2,6-bisphosphate 2-phosphatase; hypothetical protein LOC502894; LOC502894; probable fructose-2,6-bisphosphatase TIGAR; TIGAR; TP53 induced glycolysis regulatory phosphatase; TP53-induced glycolysis and apoptosis regulator; TP53-induced glycolysis regulatory phosphatase; transactivated by NS3TP2 protein; Trp53 induced glycolysis repulatory phosphatase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
319801, 57103

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q8BZA9, Q9NQ88

Gene Symbols:
TIGAR

Immunogen:
A 19 amino acid peptide from near the center of human TIGAR.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520348

--


Antigen:
MAVS

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAVS

Gene Alias:
CARD adapter inducing interferon beta; CARD adaptor inducing IFN-beta; Cardif; D430028G21Rik; IFN-B promoter stimulator 1; IFN-beta promoter stimulator-1; interferon beta promoter stimulator protein 1; interferon-beta promoter stimulator protein 1; IPS1; IPS-1; KIAA1271; MAVS; mitochondrial antiviral signaling protein; mitochondrial anti-viral signaling protein; mitochondrial antiviral-signaling protein; Putative NF-kappa-B-activating protein 031N; virus-induced signaling adapter; virus-induced signaling adaptor; virus-induced-signaling adapter; VISA

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
228607, 311430, 57506

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q66HG9, Q7Z434, Q8VCF0

Gene Symbols:
MAVS

Immunogen:
A 13 amino acid peptide from near the amino terminus of human VISA.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG