PIPA520348

MAVS Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA520348-Each-of-1 In Stock ₹ 47,015.22

PIPA520348 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

MAVS

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MAVS

Gene Alias

CARD adapter inducing interferon beta; CARD adaptor inducing IFN-beta; Cardif; D430028G21Rik; IFN-B promoter stimulator 1; IFN-beta promoter stimulator-1; interferon beta promoter stimulator protein 1; interferon-beta promoter stimulator protein 1; IPS1; IPS-1; KIAA1271; MAVS; mitochondrial antiviral signaling protein; mitochondrial anti-viral signaling protein; mitochondrial antiviral-signaling protein; Putative NF-kappa-B-activating protein 031N; virus-induced signaling adapter; virus-induced signaling adaptor; virus-induced-signaling adapter; VISA

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

228607, 311430, 57506

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q66HG9, Q7Z434, Q8VCF0

Gene Symbols

MAVS

Immunogen

A 13 amino acid peptide from near the amino terminus of human VISA.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • A suggested positive control is A-20 cell lysate
  • PA5-20348 can be used with blocking peptide PEP-0468
  • Two distinct signaling pathways activate the host innate immunity against viral infection
  • One pathway is reliant on members of the Toll-like receptor (TLR) family while the other uses the RNA helicase RIG-I as a receptor for intracellular viral double-stranded RNA as a trigger for the immune response
  • MAVS is a mitochondrial membrane protein that was identified as a critical component in the IFN beta signaling pathways that recruits IRF-3 to RIG-I, leading to its activation and that of NF-kappa-B
  • MAVS is also thought to interact with other components of the innate immune pathway such as the TLR adapter protein TRIF, TRAF2 and TRAF6
  • MAVS also interacts with the IKK-alpha, IKK-beta and IKK-iota kinases through its C-terminal region
  • Cleavage of this region by the Hepatitis C virus (HCV) protease allows HCV to escape the host immune system
  • Multiple isoforms of MAVS are known to exist.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA520348

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Antigen:
MAVS

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAVS

Gene Alias:
CARD adapter inducing interferon beta; CARD adaptor inducing IFN-beta; Cardif; D430028G21Rik; IFN-B promoter stimulator 1; IFN-beta promoter stimulator-1; interferon beta promoter stimulator protein 1; interferon-beta promoter stimulator protein 1; IPS1; IPS-1; KIAA1271; MAVS; mitochondrial antiviral signaling protein; mitochondrial anti-viral signaling protein; mitochondrial antiviral-signaling protein; Putative NF-kappa-B-activating protein 031N; virus-induced signaling adapter; virus-induced signaling adaptor; virus-induced-signaling adapter; VISA

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
228607, 311430, 57506

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q66HG9, Q7Z434, Q8VCF0

Gene Symbols:
MAVS

Immunogen:
A 13 amino acid peptide from near the amino terminus of human VISA.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520350

--


Antigen:
PD-1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Pdcd1

Gene Alias:
CD279; EGK_05005; hPD1; hPD-1; hPD-l; hSLE1; Ly101; mPD-1; PD1; PD-1; Pdc1; Pdcd1; programmed cell death 1; programmed cell death 1 protein; programmed cell death protein 1; programmed cell death protein 1-like; programmed death 1; Protein PD1; protein PD-1; sCD279; SLEB2; soluble CD279; systemic lupus erythematosus susceptibility 2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18566, 301626, 5133

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q02242, Q15116

Gene Symbols:
Pdcd1

Immunogen:
A 16 amino acid peptide from near the carboxy terminus of human PD-1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520352

--


Antigen:
BRSK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Brsk1

Gene Alias:
BR serine/threonine kinase 1; BR serine/threonine-protein kinase 1; Brain-selective kinase 1; brain-specific serine/threonine-protein kinase 1; Brsk1; Gm1100; hSAD1; KIAA1811; protein kinase SAD1A; RGD1563268; SAD1; SAD1 homolog; SAD1 kinase; SAD1A; SADB; SAD-B; SadB kinase short isoform; serine/threonine kinase SADB; serine/threonine kinase SAD-B; serine/threonine-protein kinase BRSK1; Serine/threonine-protein kinase SAD-B; synapses of Amphids Defective homolog 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
381979, 499073, 84446

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
B2DD29, Q5RJI5, Q8TDC3

Gene Symbols:
Brsk1

Immunogen:
a 28 amino acid peptide from near the carboxy terminus of human BRSK1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520353

--


Antigen:
BRSK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Brsk1

Gene Alias:
BR serine/threonine kinase 1; BR serine/threonine-protein kinase 1; Brain-selective kinase 1; brain-specific serine/threonine-protein kinase 1; Brsk1; Gm1100; hSAD1; KIAA1811; protein kinase SAD1A; RGD1563268; SAD1; SAD1 homolog; SAD1 kinase; SAD1A; SADB; SAD-B; SadB kinase short isoform; serine/threonine kinase SADB; serine/threonine kinase SAD-B; serine/threonine-protein kinase BRSK1; Serine/threonine-protein kinase SAD-B; synapses of Amphids Defective homolog 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
381979, 499073, 84446

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
B2DD29, Q5RJI5, Q8TDC3

Gene Symbols:
Brsk1

Immunogen:
a 28 amino acid peptide from near the center of human BRSK1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG