PIPA520364

NPAS3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA520364-Each-of-1 In Stock ₹ 44,790.66

PIPA520364 - Each of 1

₹ 44,790.66

In Stock

Quantity

1

Base Price: ₹ 44,790.66

GST (18%): ₹ 8,062.319

Total Price: ₹ 52,852.979

Antigen

NPAS3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NPAS3

Gene Alias

4930423H22Rik; Basic-helix-loop-helix-PAS protein MOP6; bHLHe12; Class E basic helix-loop-helix protein 12; member of PAS protein 6; MOP6; neuronal PAS domain protein 3; neuronal PAS domain-containing protein 3; Neuronal PAS3; NPAS3; PAS domain-containing protein 6; PASD6

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

27386, 299016, 64067

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q8IXF0, Q9QZQ0

Gene Symbols

NPAS3

Immunogen

a 28 amino acid peptide from near the amino terminus of human NPAS3.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • A suggested positive control is SK-N-SH cell lysate
  • PA5-20364 can be used with blocking peptide PEP-0484
  • Neuronal PAS domain protein 3 (NPAS3) is a brain-enriched basic helix-loop-helix PAS domain transcription factor and is broadly expressed in the developing neuroepithelium and has recently found to be disrupted by genetic translocation in a family affected with schizophrenia
  • It was recently shown to be involved in the regulation of FGF signaling in the dentate gyrus by controlling the expression of the FGF receptor subtype 1 and in turn neurogenesis emanating from this region
  • NPAS3-null mice were growth-retarded and displayed brain defects that included reduced size of the anterior hippocampus, hypoplasia of the corpus callosum, and enlargement of the ventricles, as well as several behavioral abnormalities
  • Furthermore, these NPAS3-null mice also exhibited disruptions in several neurosignaling pathways involving glutamate, dopamine, and serotonin
  • These results demonstrate the essential role played by NPAS3 during structural and functional brain development
  • At least three isoforms of NPAS3 are known to exist.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA520364

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Antigen:
NPAS3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NPAS3

Gene Alias:
4930423H22Rik; Basic-helix-loop-helix-PAS protein MOP6; bHLHe12; Class E basic helix-loop-helix protein 12; member of PAS protein 6; MOP6; neuronal PAS domain protein 3; neuronal PAS domain-containing protein 3; Neuronal PAS3; NPAS3; PAS domain-containing protein 6; PASD6

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27386, 299016, 64067

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q8IXF0, Q9QZQ0

Gene Symbols:
NPAS3

Immunogen:
a 28 amino acid peptide from near the amino terminus of human NPAS3.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520366

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Antigen:
Nogo-A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Rtn4

Gene Alias:
1110020G17Rik; AA407876; AA409940; AA960376; ASY; C130026I10Rik; Foocen; glut4 vesicle 20 kDa protein; GLUT4 vesicle 20kDa protein; Human NogoA; KIAA0886; mKIAA0886; mKIAA4153; My043; My043 protein; Nbla00271; Nbla10545; neurite growth inhibitor 220; neurite outgrowth inhibitor; Neuroendocrine-specific protein; Neuroendocrine-specific protein C homolog; NgA; NI220/250; NI-220/250; NI-250; Nogo; Nogo protein; Nogo-A; Nogo-B; NOGOC; Nogo-C; NSP; NSP-CL; r; rat N; rat NogoA; reticulon 4; reticulon 5; reticulon-4; Reticulon-5; RTN4; RTN4-A; RTN4-B1; RTN4-B2; RTN4-C; RTN-x; SP1507; Vp20

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57142, 68585, 83765

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q99P72, Q9JK11, Q9NQC3

Gene Symbols:
Rtn4

Immunogen:
A 23 amino acid peptide from near the amino terminus of human NogoA.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520369

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Antigen:
ORAI2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ORAI2

Gene Alias:
A730041O15Rik; C7orf19; calcium release-activated calcium channel 2; calcium release-activated calcium modulator 2 protein; CAP-binding protein complex interacting protein 2; CAP-binding protein complex-interacting protein 2; CBCIP2; H_NH0514P08.8; MEM142B; ORAI calcium release-activated calcium modulator 2; ORAI2; PP1729; Protein orai-2; putative protein ORAI2-2; RGD1310213; TMEM142B; Transmembrane protein 142B

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
269717, 80228

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q8BH10, Q96SN7

Gene Symbols:
ORAI2

Immunogen:
A 15 amino acid peptide from near the carboxy terminus of human ORAI2.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520370

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Antigen:
ORAI3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ORAI3

Gene Alias:
9930124N15; BC061259; calcium release-activated calcium channel 3; calcium release-activated calcium modulator 3 protein; ORAI calcium release-activated calcium modulator 3; ORAI3; Protein orai-3; RGD1306538; Tmem142c; Transmembrane protein 142C

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
269999, 309000, 93129

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q6AXR8, Q6P8G8, Q9BRQ5

Gene Symbols:
ORAI3

Immunogen:
A 15 amino acid peptide from near the amino terminus of human ORAI3.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG