PIPA520683

SPG11 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA520683-Each-of-1 In Stock ₹ 44,790.66

PIPA520683 - Each of 1

₹ 44,790.66

In Stock

Quantity

1

Base Price: ₹ 44,790.66

GST (18%): ₹ 8,062.319

Total Price: ₹ 52,852.979

Antigen

SPG11

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SPG11

Gene Alias

6030465E24Rik; A330015I11; ALS5; C530005A01Rik; CMT2X; Colorectal carcinoma-associated protein; KIAA1840; RGD1562529; spastic paraplegia 11; spastic paraplegia 11 (autosomal recessive); spastic paraplegia 11 protein; Spastic paraplegia 11 protein homolog; spatacsin; Spg11

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

214585, 311372, 80208

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q3UHA3, Q96JI7

Gene Symbols

SPG11

Immunogen

A 15 amino acid synthetic peptide near the carboxy terminus of human SPG11

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • A suggested positive control is mouse heart tissue lysate
  • PA5-20683 can be used with blocking peptide PEP-0799
  • Hereditary spastic paraplegias (HSPs) are genetically and phenotypically heterogeneous disorders
  • Spastic paraplegia with thinning of the corpus callosum (ARHSP-TCC) is a relatively frequent form of complicated hereditary spastic paraplegia (cHSP) in which mental retardation and muscle stiffness at onset are followed by slowly progressive paraparesis and cognitive deterioration
  • Mutations of the SPG11 gene encoding the spatacsin protein have been identified as a major cause of HSP-TCC
  • Spatacsin is a potential transmembrane protein that is phosphorylated upon DNA damage
  • It is expressed in all structures of the brain, with a high expression in the cerebellum
  • SPG11 mutations may occur more frequently in familial than sporadic forms of cHSP without TCC
  • Kjellin syndrome is found to be associated with mutations in not only the SPG15 gene but also SPG11 gene
  • Recent studies show Parkinsonism may initiate SPG11-linked HSP TCC and that SPG11 may cause juvenile Parkinsonism.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA520683

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Antigen:
SPG11

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SPG11

Gene Alias:
6030465E24Rik; A330015I11; ALS5; C530005A01Rik; CMT2X; Colorectal carcinoma-associated protein; KIAA1840; RGD1562529; spastic paraplegia 11; spastic paraplegia 11 (autosomal recessive); spastic paraplegia 11 protein; Spastic paraplegia 11 protein homolog; spatacsin; Spg11

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
214585, 311372, 80208

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q3UHA3, Q96JI7

Gene Symbols:
SPG11

Immunogen:
A 15 amino acid synthetic peptide near the carboxy terminus of human SPG11

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA520684

--


Antigen:
PDCD5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PDCD5

Gene Alias:
2200003D22Rik; AA408513; PDCD5; programmed cell death 5; programmed cell death protein 5; Protein TFAR19; TF1 cell apoptosis-related gene 19; TF-1 cell apoptosis-related protein 19; Tfar19; TFAR19 novel apoptosis-related

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
292814, 56330, 9141

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O14737, P56812

Gene Symbols:
PDCD5

Immunogen:
A 13 amino acid peptide from near the amino terminus of human PDCD5.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA520685

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Antigen:
ZFYVE26

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ZFYVE26

Gene Alias:
4930465A13; 9330197E15Rik; A630028O16Rik; FYVE domain-containing centrosomal protein; FYVE-CENT; Gm893; Kiaa0321; mKIAA0321; Spastizin; SPG15; Zfyve26; Zinc finger FYVE domain-containing protein 26; zinc finger FYVE-type containing 26; zinc finger, FYVE domain containing 26

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
211978, 23503, 314265

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
D4A8G9, Q5DU37, Q68DK2

Gene Symbols:
ZFYVE26

Immunogen:
A 16 amino acid peptide near the carboxy terminus of human SPG15.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA520691

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Antigen:
FNIP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FNIP2

Gene Alias:
D630023B12Rik; FNIP1-like protein; Fnip2; Fnipl; folliculin interacting protein 2; folliculin-interacting protein 2; KIAA1450; MAPO1; mKIAA1450; O6-methylguanine-induced apoptosis 1 protein; RGD1562174

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
310538, 329679, 57600

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q80TD3, Q9P278

Gene Symbols:
FNIP2

Immunogen:
An 18 amino acid peptide near the amino terminus of human FNIP2.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG