PIPA520841

FRMPD4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA520841-Each-of-1 In Stock ₹ 44,705.10

PIPA520841 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

FRMPD4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

FRMPD4

Gene Alias

FERM and PDZ domain containing 4; FERM and PDZ domain-containing protein 4; FRMPD4; KIAA0195; KIAA0316; PDZ domain-containing protein 10; PDZD10; PDZK10; Preso; PSD-95-interacting FERM and PDZ domain protein; PSD-95-interacting regulator of spine morphogenesis; TMEM94; Transmembrane protein 94

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

9758

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q14CM0

Gene Symbols

FRMPD4

Immunogen

An 18 amino acid peptide from near the center of human FRMPD4.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • A suggested positive control is SK-N-SH cell lysate
  • PA5-20841 can be used with blocking peptide PEP-0955
  • The FERM and PDZ domain containing (FRMPD) protein family consists of four proteins that contain a FERM (Four-point-one, erzin, radixin, moesin) domain and at least one PDZ (PSD-95/Discs large/Zonula-occuldens-1) domain
  • FRMPD4, also known as Preso, also contains another protein interaction domain termed WW (domain with two conserved Trp residues) at its amino terminus
  • It was identified through a yeast two-hybrid screen using the PDZ domain of PSD-95 as bait and is highly expressed in multiple regions of the brain and is enriched in the postsynaptic density (PSD) fractions
  • Overexpression of FRMPD4 in cultured hippocampal neurons significantly increased the linear density of dendritic spines without changing their length and width; conversely, knockdown experiments using RNAi caused a decrease in spine density, indicating FRMPD4 positively regulates dendritic spine density but not morphology
  • The decreased level of FRMPD4 also resulted in reduced levels of excitatory synaptic transmission, suggesting that FRMPD4 is required for maintenance of excitatory synaptic transmission.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA520841

--


Antigen:
FRMPD4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FRMPD4

Gene Alias:
FERM and PDZ domain containing 4; FERM and PDZ domain-containing protein 4; FRMPD4; KIAA0195; KIAA0316; PDZ domain-containing protein 10; PDZD10; PDZK10; Preso; PSD-95-interacting FERM and PDZ domain protein; PSD-95-interacting regulator of spine morphogenesis; TMEM94; Transmembrane protein 94

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9758

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q14CM0

Gene Symbols:
FRMPD4

Immunogen:
An 18 amino acid peptide from near the center of human FRMPD4.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520843

--


Antigen:
SRPX

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SRPX

Gene Alias:
down-regulated by v-src; Drs; DRS protein; drs-1; drs-2; epididymis secretory sperm binding protein Li 83p; ETX1; HEL-S-83p; mDRS-1; mDRS-2; SRPX; SRPX1; sushi repeat containing protein, X-linked; sushi repeat-containing protein SRPX; sushi-repeat containing protein, X-linked; sushi-repeat-containing protein; sushi-repeat-containing protein SRPX; sushi-repeat-containing protein X chromosome; sushi-repeat-containing protein, X chromosome; sushi-repeat-containing protein, X-chromosome; sushi-repeat-containing protein, X-linked

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
51795, 64316, 8406

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P78539, Q63769, Q9R0M3

Gene Symbols:
SRPX

Immunogen:
A 13 amino acid peptide from near the amino terminus of human SRPX1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA520845

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Antigen:
FAM59A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GAREM1

Gene Alias:
C18orf11; C86169; Fam59a; family with sequence similarity 59, member A; GAREM; GAREM1; Gm944; GRB2 associated regulator of MAPK1 1; GRB2 associated regulator of MAPK1 subtype 1; GRB2 associated, regulator of MAPK1; Grb2-associated and regulator of Erk/MAPK; GRB2-associated and regulator of MAPK protein; GRB2-associated and regulator of MAPK protein 1; GRB2-associated and regulator of MAPK1; Kiaa4238; mKIAA4238; protein FAM59A

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
381126, 64762, 679154

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q3UFT3, Q9H706

Gene Symbols:
GAREM1

Immunogen:
A 19 amino acid peptide from near the carboxy terminus of human FAM59A.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520846

--


Antigen:
FAM59B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GAREM2

Gene Alias:
FAM59B; family with sequence similarity 59, member B; Garem2; Gareml; Gm444; GRB2 associated regulator of MAPK1 2; GRB2 associated regulator of MAPK1 subtype 2; GRB2 associated, regulator of MAPK1-like; GRB2-associated and regulator of MAPK protein 2; GRB2-associated and regulator of MAPK protein-like; GRB2-associated and regulator of MAPK1-like; HRIHFB2063; KIAA2038; protein FAM59B

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
150946, 242915, 362801

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q6PAJ3, Q75VX8

Gene Symbols:
GAREM2

Immunogen:
A 19 amino acid peptide from near the carboxy terminus of human FAM59B.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG