PIPA520857

PLEKHM1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA520857-Each-of-1 In Stock ₹ 44,705.10

PIPA520857 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

PLEKHM1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PLEKHM1

Gene Alias

162 kDa adapter protein; AP162; B2; BC038943; D330036J23Rik; KIAA0356; OPTB6; PH domain-containing family M member 1; pleckstrin homology and RUN domain containing M1; pleckstrin homology domain containing, family M (with RUN domain) member 1; pleckstrin homology domain-containing family M member 1; PLEKHM1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

9842

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q9Y4G2

Gene Symbols

PLEKHM1

Immunogen

An 18 amino acid peptide from near the amino terminus of human PLEKHM1.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • A suggested positive control is human lung tissue lysate
  • PA5-20857 can be used with blocking peptide PEP-0971
  • PLEKHM1 is a member of the M family of Pleckstrin homolog domain-containing proteins, a group of proteins containing a RUN domain, two pleckstrin homology domains, and a cysteine-rich domain
  • It was identified through segregation analysis as a cause of osteopetrosis in humans
  • PLEKHM1 co-localizes with Rab7 to late endosomal/lysosomal vesicles in HEK293 and osteoclast-like cells, with this co-localization dependent on the prenylation of Rab7
  • Monocytes from a patient homozygous for a mutated form of PLEKHM1differentiated into osteoclasts normally, but failed to form ruffled borders and showed little evidence of bone resorption when cultured on dentine discs
  • Another mutation of PLEKHM1 impaired vesicular acidification and increased TRACP secretion in osteoclasts, suggesting that PLEKHM1 has critical roles in endosomal maturation and may be important in osteoclast-osteoblast cross-talk.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA520857

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Antigen:
PLEKHM1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PLEKHM1

Gene Alias:
162 kDa adapter protein; AP162; B2; BC038943; D330036J23Rik; KIAA0356; OPTB6; PH domain-containing family M member 1; pleckstrin homology and RUN domain containing M1; pleckstrin homology domain containing, family M (with RUN domain) member 1; pleckstrin homology domain-containing family M member 1; PLEKHM1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9842

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q9Y4G2

Gene Symbols:
PLEKHM1

Immunogen:
An 18 amino acid peptide from near the amino terminus of human PLEKHM1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520858

--


Antigen:
TMEM38A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Tmem38a

Gene Alias:
1110001E17Rik; 27 kDa sarcoplasmic reticulum protein; AI413399; mg33a; Mitsugumin33A; Mitsugumin-33A; RGD1307901; sarcoplasmic reticulum protein 27; SPR-27; Srp-27; TMEM38A; tmem38a {ECO:0000250; Transmembrane protein 38A; TRICA; TRIC-A; trimeric intracellular cation channel type A; UniProtKB:Q3TMP8}

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
306327, 74166, 79041

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
A6ZIQ8, Q3TMP8, Q9H6F2

Gene Symbols:
Tmem38a

Immunogen:
A 17 amino acid peptide from near the carboxy terminus of human TMEM38A.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520859

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Antigen:
TMEM38B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TMEM38B

Gene Alias:
1600017F22Rik; AA437809; AV051057; bA219P18.1; C9orf87; D4Ertd89e; mg33b; Mitsugumin33B; Mitsugumin-33B; OI14; RGD1305703; RP11-219P18.1; TMEM38B; Transmembrane protein 38B; TRICB; TRIC-B; trimeric intracellular cation channel type B

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
362521, 52076, 55151

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q68FV1, Q9DAV9, Q9NVV0

Gene Symbols:
TMEM38B

Immunogen:
A 17 amino acid peptide from near the carboxy terminus of human TMEM38B.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520861

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Antigen:
RHBDD2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RHBDD2

Gene Alias:
0610011L13Rik; AI480532; H_RG122E10.2a; H_RG122E10.2b; NPD007; Rhbdd2; Rhbdl7; rhomboid domain containing 2; rhomboid domain-containing protein 2; rhomboid, veinlet-like 7; rhomboid-like protein 7; upregulated during skeletal muscle growth 1; Usmg1; WUGSC:H_RG122E10.2a; WUGSC:H_RG122E10.2b

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
215160, 360793, 57414

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q6NTF9, Q8VEK2

Gene Symbols:
RHBDD2

Immunogen:
An 18 amino acid peptide from near the center of human RHBDD2.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG