PIPA520889

Nanog Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA520889-Each-of-1 In Stock ₹ 47,699.70

PIPA520889 - Each of 1

₹ 47,699.70

In Stock

Quantity

1

Base Price: ₹ 47,699.70

GST (18%): ₹ 8,585.946

Total Price: ₹ 56,285.646

Antigen

Nanog

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NANOG

Gene Alias

2410002E02Rik; early embryo specific expression NK family; early embryo specific expression NK-type homeobox protein; Ecat4; ENK; ES cell-associated protein 4; FLJ12581; HGNC:20857; hNanog; Homeobox protein NANOG; homeobox transcription factor Nanog; homeobox transcription factor Nanog-delta 48; Nanog; Nanog homeobox

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

414065, 71950, 79923

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q80Z64, Q9H9S0

Gene Symbols

NANOG

Immunogen

A 19 amino acid peptide near the center of human NANOG.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • A suggested positive control is human spleen tissue lysate
  • PA5-20889 can be used with blocking peptide PEP-1003
  • NANOG (Nanog homeobox) is a divergent homeodomain protein that directs pluripotency and differentiation of undifferentiated embryonic stem cells
  • NANOG mRNA is present in pluripotent mouse and human cell lines, and absent from differentiated cells
  • Human NANOG protein shares 52% overall amino acid identity with the mouse protein, and 85% identity in the homeodomain
  • Human NANOG maps to gene locus 12p13.31, while the mouse NANOG maps to gene loci 6 F2
  • Murine embryonic NANOG expression is detected in the inner cell mass of the blastocyst
  • Research studies have shown that high levels of human NANOG expression in the undifferentiated N-Tera embryonal carcinoma cell line
  • Further, NANOG is a transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal
  • The role of NANOG in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of several degenerative diseases
  • Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing POU5F1 (also known as Oct-4), another germline-specific transcription factor, and the transcription factors Sox2, Klf4 and Lin28 along with c-Myc in mouse fibroblasts
  • Experiments have demonstrated that iPS cells could be generated using expression plasmids expressing NANOG, Sox2, KlfF4 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine
  • When overexpressed, NANOG promotes cells to enter into S phase and proliferation
  • Diseases associated with dysfunction in the NANOG protein include tetracarcinoma and germ cell/embryonal cancer.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA520889

--


Antigen:
Nanog

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NANOG

Gene Alias:
2410002E02Rik; early embryo specific expression NK family; early embryo specific expression NK-type homeobox protein; Ecat4; ENK; ES cell-associated protein 4; FLJ12581; HGNC:20857; hNanog; Homeobox protein NANOG; homeobox transcription factor Nanog; homeobox transcription factor Nanog-delta 48; Nanog; Nanog homeobox

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
414065, 71950, 79923

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q80Z64, Q9H9S0

Gene Symbols:
NANOG

Immunogen:
A 19 amino acid peptide near the center of human NANOG.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520891

--


Antigen:
CDX2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDX2

Gene Alias:
caudal type homeo box 2; caudal type homeo box transcription factor 2; caudal type homeobox 2; caudal type homeobox transcription factor 2; caudal-type homeobox protein 2; CDX2; Cdx-2; CDX2/AS; CDX3; CDX-3; HGNC:1806; homeobox protein CDX-2; homeobox protein miniCDX2; homeobox transcription factor

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1045, 12591, 66019

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P43241, Q99626

Gene Symbols:
CDX2

Immunogen:
A 16 amino acid peptide near the carboxy terminus of human CDX2.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520892

--


Antigen:
GATA3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GATA3

Gene Alias:
EGK_19445; GATA binding factor-3; GATA binding protein 3; GATA binding protein-3; GATA3; Gata-3; GATA-binding factor 3; GATA-binding protein 3; HDR; HDRS; jal; MGC2346; MGC5199; MGC5445; Trans-acting T-cell-specific transcription factor GATA-3; Transacting T-cell-specific transcription factor GATA-3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14462, 2625, 85471

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
ChIP Assay, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P23771, P23772

Gene Symbols:
GATA3

Immunogen:
A 17 amino acid peptide near the carboxy terminus of human GATA3.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520893

--


Antigen:
ARHGAP18

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ARHGAP18

Gene Alias:
4833419J07Rik; AI314906; AI843501; Arhgap18; bA307O14.2; MacGAP; Rho GTPase activating protein 18; rho GTPase-activating protein 18; Rho-type GTPase-activating protein 18; SENEX

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
293947, 73910, 93663

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q8K0Q5, Q8N392

Gene Symbols:
ARHGAP18

Immunogen:
A 15 amino acid peptide near the carboxy terminus of human ARHGAP18.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG