PIPA521005

ALKBH2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA521005-Each-of-1 In Stock ₹ 45,304.02

PIPA521005 - Each of 1

₹ 45,304.02

In Stock

Quantity

1

Base Price: ₹ 45,304.02

GST (18%): ₹ 8,154.724

Total Price: ₹ 53,458.744

Antigen

ALKBH2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ALKBH2

Gene Alias

2OG-Fe(II) oxy DC1; 9530023G02; Abh2; AlkB homolog 2; alkB homolog 2, alpha-ketoglutarate dependent dioxygenase; alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase; alkB, alkylation repair homolog 2; alkB, alkylation repair homolog 2 (E. coli); ALKBH2; Alkylated DNA repair protein alkB homolog 2; alpha-ketoglutarate-dependent dioxygenase alkB homolog 2; AU016977; DNA oxidative demethylase ALKBH2; mABH2; oxy DC1; RGD1306377

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

121642, 231642, 304578

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q6NS38, Q6P6J4

Gene Symbols

ALKBH2

Immunogen

A 15 amino acid peptide near the carboxy terminus of human ALKBH2.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • A suggested positive control is human kidney tissue lysate
  • PA5-21005 can be used with blocking peptide PEP-1119
  • The E
  • coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA; ALKBH2 and ALKBH3 are mammalian homologs of AlkB that catalyze the removal of 1-methyladenine and 3-methylcytosine, modifications that left unchecked could lead to cancerous cells
  • Mutations in both ALKBH2 and ALKBH3 have been observed in pediatric brain tumors indicating that these proteins are important in the prevention of cancer formation
  • Like the histone demethylase JMJD1A, ALKBH2 is a non-heme iron enzyme that is inhibited by Nickel ions, suggesting that inhibition of ALKBH2 by Nickel ions may play a role in the development of cancer
  • Conversely, ALKBH2 mRNA and protein levels are increased glioma cells following Photofrin-mediated photodynamic therapy, an adjuvant therapy in cancer treatment, suggesting that down-regulating ALKBH2 expression in cancer cells may enhance the anti-cancer effectiveness of this treatment.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA521005

--


Antigen:
ALKBH2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ALKBH2

Gene Alias:
2OG-Fe(II) oxy DC1; 9530023G02; Abh2; AlkB homolog 2; alkB homolog 2, alpha-ketoglutarate dependent dioxygenase; alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase; alkB, alkylation repair homolog 2; alkB, alkylation repair homolog 2 (E. coli); ALKBH2; Alkylated DNA repair protein alkB homolog 2; alpha-ketoglutarate-dependent dioxygenase alkB homolog 2; AU016977; DNA oxidative demethylase ALKBH2; mABH2; oxy DC1; RGD1306377

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
121642, 231642, 304578

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q6NS38, Q6P6J4

Gene Symbols:
ALKBH2

Immunogen:
A 15 amino acid peptide near the carboxy terminus of human ALKBH2.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA521006

--


Antigen:
VENTX

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ventx

Gene Alias:
hemopoietic progenitor homeobox protein VENTX2; homeobox protein VENTX; HPX42B; NA88A; VENT homeobox; VENT homeobox homolog; VENT-like homeobox 2; VENT-like homeobox protein 2; VENTX; VENTX2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
110333234, 27287

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O95231

Gene Symbols:
Ventx

Immunogen:
A 16 amino acid peptide near the center of human VENTX.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA521007

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Antigen:
CRISP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CRISP2

Gene Alias:
Cancer/testis antigen 36; CRISP2; CRISP-2; Crisp2l; CT36; cysteine rich secretory protein 2; cysteine-rich secretory protein 2; cysteine-rich secretory protein 2-like; GAPDL5; glyceraldehyde-3-phosphate dehydrogenase-like 5; MGC111136; OTTHUMP00000016589; testicular tissue protein Li 43; testis specific gene 1; testis specific protein 1; testis specific protein 1 (probe H4-1 p3-1); testis-specific protein TPX-1; TPX1; Tpx-1; TSP1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7180

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P16562

Gene Symbols:
CRISP2

Immunogen:
A 15 amino acid peptide near the amino terminus of human CRISP2.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA521009

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Antigen:
SESTD1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Sestd1

Gene Alias:
1500031J16Rik; A930010O20; EGK_04585; Huntingtin-interacting protein-like protein; protein Solo; RGD1562244; SEC14 and spectrin domain containing 1; SEC14 and spectrin domains 1; SEC14 domain and spectrin repeat-containing protein 1; Sestd1; SOLO; Solo/Trio8

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
228071, 295678, 91404

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q80UK0, Q86VW0

Gene Symbols:
Sestd1

Immunogen:
A 15 amino acid peptide near the carboxy terminus of human SESTD1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG