PIPA522015
MST1 (STK4) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA522015-Each-of-1 | In Stock | ₹ 49,795.92 |
PIPA522015 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,795.92
GST (18%): ₹ 8,963.266
Total Price: ₹ 58,759.186
Antigen
MST1 (STK4)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Stk4
Gene Alias
AI447339; AU020804; EC 2.7.11.1; Kas-2; kinase MST1; kinase responsive to stress 2; KRS2; Mammalian STE20-like protein kinase 1; mammalian sterile 20-like 1; MST1; MST-1; MST1/C; MST1/N; serine/threonine kinase 4; serine/threonine-protein kinase 4; Serine/threonine-protein kinase 4 18kDa subunit; Serine/threonine-protein kinase 4 37kDa subunit; Serine/threonine-protein kinase Krs-2; STE20-like kinase MST1; sterile 20-like kinase 1; STK4; TIIAC; Yeast Sps1/Ste20-related kinase 3; Ysk3
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
6789
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
1 mg/mL
Formulation
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q13043
Gene Symbols
Stk4
Immunogen
Synthetic peptide corresponding to a region within amino acids 324 and 418 of STK4 (Uniprot ID#Q13043)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: HepG2, mouse brain
- Predicted reactivity: Mouse (100%), Rat (100%), Chicken (100%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- STK4 (MST1) is a serine/threonine kinase which may be involved in apoptosis
- It is possible that this protein induces the chromatin condensation observed in this process
- STK4 is a stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation
- It is a key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis
- The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ
- Phosphorylation of YAP1 by LATS2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration
- STK3/MST2 and STK4/MST1 are required to repress proliferation of mature hepatocytes, to prevent activation of facultative adult liver stem cells (oval cells), and to inhibit tumor formation.
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Antigen: MST1 (STK4)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Stk4
Gene Alias: AI447339; AU020804; EC 2.7.11.1; Kas-2; kinase MST1; kinase responsive to stress 2; KRS2; Mammalian STE20-like protein kinase 1; mammalian sterile 20-like 1; MST1; MST-1; MST1/C; MST1/N; serine/threonine kinase 4; serine/threonine-protein kinase 4; Serine/threonine-protein kinase 4 18kDa subunit; Serine/threonine-protein kinase 4 37kDa subunit; Serine/threonine-protein kinase Krs-2; STE20-like kinase MST1; sterile 20-like kinase 1; STK4; TIIAC; Yeast Sps1/Ste20-related kinase 3; Ysk3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 6789
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q13043
Gene Symbols: Stk4
Immunogen: Synthetic peptide corresponding to a region within amino acids 324 and 418 of STK4 (Uniprot ID#Q13043)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
MST1 (STK4)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Stk4
Gene Alias:
AI447339; AU020804; EC 2.7.11.1; Kas-2; kinase MST1; kinase responsive to stress 2; KRS2; Mammalian STE20-like protein kinase 1; mammalian sterile 20-like 1; MST1; MST-1; MST1/C; MST1/N; serine/threonine kinase 4; serine/threonine-protein kinase 4; Serine/threonine-protein kinase 4 18kDa subunit; Serine/threonine-protein kinase 4 37kDa subunit; Serine/threonine-protein kinase Krs-2; STE20-like kinase MST1; sterile 20-like kinase 1; STK4; TIIAC; Yeast Sps1/Ste20-related kinase 3; Ysk3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
6789
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
1 mg/mL
Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q13043
Gene Symbols:
Stk4
Immunogen:
Synthetic peptide corresponding to a region within amino acids 324 and 418 of STK4 (Uniprot ID#Q13043)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: MAP4K5
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Map4k5
Gene Alias: 4432415E19Rik; fl74c10; GCKR; germinal center kinase-related; KHS; KHS1; Kinase homologous to SPS1/STE20; LOW QUALITY PROTEIN: mitogen-activated protein kinase kinase kinase kinase 5; map4k5; MAPK/ERK kinase kinase kinase 5; MAPKKKK5; MEK kinase kinase 5; MEKKK 5; mitogen-activated protein kinase kinase kinase kinase 5; RGD1562028; wu:fl74c10; zgc:55719; zgc:55985
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11183
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q9Y4K4
Gene Symbols: Map4k5
Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 417 and 482 of KHS
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MAP4K5
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Map4k5
Gene Alias:
4432415E19Rik; fl74c10; GCKR; germinal center kinase-related; KHS; KHS1; Kinase homologous to SPS1/STE20; LOW QUALITY PROTEIN: mitogen-activated protein kinase kinase kinase kinase 5; map4k5; MAPK/ERK kinase kinase kinase 5; MAPKKKK5; MEK kinase kinase 5; MEKKK 5; mitogen-activated protein kinase kinase kinase kinase 5; RGD1562028; wu:fl74c10; zgc:55719; zgc:55985
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11183
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
1 mg/mL
Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q9Y4K4
Gene Symbols:
Map4k5
Immunogen:
Synthetic peptide contain a sequence corresponding to a region within amino acids 417 and 482 of KHS
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: DNase I
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DNASE1
Gene Alias: AI788650; deoxyribonuclease; Deoxyribonuclease 1; deoxyribonuclease I; Deoxyribonuclease1; Deoxyribonuclease-1; DeoxyribonucleaseI; DNASE 1; DNase I; DNase I lysosomal; DNase I, lysosomal; Dnase1; DNaseI; DNL 1; DNL1; Dornase alfa; DRNI; epithelial lens deoxyribonuclease I; FLJ38093; human urine deoxyribonuclease I; pancreatic deoxyribonuclease I
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1773
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.19 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: P24855
Gene Symbols: DNASE1
Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 282 of DNase I (Uniprot ID#P24855)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
DNase I
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DNASE1
Gene Alias:
AI788650; deoxyribonuclease; Deoxyribonuclease 1; deoxyribonuclease I; Deoxyribonuclease1; Deoxyribonuclease-1; DeoxyribonucleaseI; DNASE 1; DNase I; DNase I lysosomal; DNase I, lysosomal; Dnase1; DNaseI; DNL 1; DNL1; Dornase alfa; DRNI; epithelial lens deoxyribonuclease I; FLJ38093; human urine deoxyribonuclease I; pancreatic deoxyribonuclease I
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1773
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.19 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.:
P24855
Gene Symbols:
DNASE1
Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 282 of DNase I (Uniprot ID#P24855)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: AP1S2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: AP1S2
Gene Alias: adapter-related protein complex 1 sigma-1B subunit; adaptor protein complex AP-1 sigma-1B subunit; Adaptor protein complex AP-1 subunit sigma-1B; adaptor related protein complex 1 sigma 2 subunit; adaptor-related protein complex 1 sigma 2 subunit; adaptor-related protein complex 1 subunit sigma-1B; adaptor-related protein complex 1, sigma 2 subunit; AP-1 complex subunit sigma-2; AP1S2; clathrin adaptor complex AP1 sigma 1B subunit; clathrin assembly protein complex 1 sigma-1B small chain; DC22; golgi adaptor HA1/AP1 adaptin sigma-1B subunit; MGC:1902; MRX59; MRXS21; MRXS5; MRXSF; PGS; Sigma 1B subunit of AP-1 clathrin; SIGMA1B; sigma1B-adaptin; Sigma-adaptin 1B
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 8905
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 0.53 mg/mL
Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: P56377
Gene Symbols: AP1S2
Immunogen: Full length human AP1S2 Recombinant protein.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
AP1S2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
AP1S2
Gene Alias:
adapter-related protein complex 1 sigma-1B subunit; adaptor protein complex AP-1 sigma-1B subunit; Adaptor protein complex AP-1 subunit sigma-1B; adaptor related protein complex 1 sigma 2 subunit; adaptor-related protein complex 1 sigma 2 subunit; adaptor-related protein complex 1 subunit sigma-1B; adaptor-related protein complex 1, sigma 2 subunit; AP-1 complex subunit sigma-2; AP1S2; clathrin adaptor complex AP1 sigma 1B subunit; clathrin assembly protein complex 1 sigma-1B small chain; DC22; golgi adaptor HA1/AP1 adaptin sigma-1B subunit; MGC:1902; MRX59; MRXS21; MRXS5; MRXSF; PGS; Sigma 1B subunit of AP-1 clathrin; SIGMA1B; sigma1B-adaptin; Sigma-adaptin 1B
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8905
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
0.53 mg/mL
Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
P56377
Gene Symbols:
AP1S2
Immunogen:
Full length human AP1S2 Recombinant protein.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG