PIPA522726

IRE1 alpha Polyclonal Antibody, DyLight™ 488, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA522726-Each-of-1 In Stock ₹ 44,790.66

PIPA522726 - Each of 1

₹ 44,790.66

In Stock

Quantity

1

Base Price: ₹ 44,790.66

GST (18%): ₹ 8,062.319

Total Price: ₹ 52,852.979

Antigen

IRE1 alpha

Classification

Polyclonal

Conjugate

DyLight 488

Gene

ERN1

Gene Alias

9030414B18Rik; AI225830; C85377; endoplasmic reticulum (ER) to nucleus signalling 1; endoplasmic reticulum to nucleus signaling 1; endoplasmic reticulum to nucleus signalling 1; endoplasmic reticulum-to-nucleus signaling 1; Endoribonuclease; ER to nucleus signalling 1; ERN1; FLJ30999; hIRE1p; inositol-requiring 1; inositol-requiring 1 alpha; inositol-requiring enzyme 1; inositol-requiring protein 1; IRE1; IRE1a; IRE1a antibody; Ire1alpha; Ire1-alpha; Ire1p; IRE1p antibody; MGC163277; MGC163279; protein kinase/endoribonuclease; RGD1559716; Serine/threonine-protein kinase; Serine/threonine-protein kinase/endoribonuclease IRE1; serine/threonine-protein kinase/endoribonuclease IRE1-like

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2081, 498013, 78943

Content And Storage

4° C, store in dark

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.2 mg/mL

Formulation

50mM sodium borate with no preservative

Gene Accession No.

O75460, Q9EQY0

Gene Symbols

ERN1

Immunogen

A synthetic peptide within the human IRE1 alpha protein (within residues 700-800).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody does not react with non-human primate samples
  • Suggested positive control: Pancreatic islets and insulinoma cells
  • ERN1 serine/threonine kinase or endoplasmic reticulum to nucleus signaling 1 is the ER to nucleus signaling 1 protein, a human homologue of the yeast Ire1 gene product which possesses intrinsic kinase activity and an endoribonuclease activity and it is important in endoplasmic reticulum-based stress signals
  • ERN1 controls IRE1 proteolysis in mammalian cells
  • ERN1 has a critical function in extraembryonic cells that is essential for fetal viability
  • Specifically, IRE1 acts as the sensor of unfolded proteins in the ER that initiates transmittance of the unfolded protein signal from the ER to the nucleus by splicing XBP1 mRNA converting it into a potent unfolded-protein response transcriptional activator
  • Null mutants are viable, but IRE1 is essential for viability under stress conditions that cause unfolded proteins to accumulate in the ER
  • Depletion of IRE1p through the expression of a dominant negative form of IRE1p has no effect on transfected cells, but cell death via apoptosis occurs under stress conditions that cause unfolded proteins to accumulate in the ER.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA522726

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Antigen:
IRE1 alpha

Classification:
Polyclonal

Conjugate:
DyLight 488

Gene:
ERN1

Gene Alias:
9030414B18Rik; AI225830; C85377; endoplasmic reticulum (ER) to nucleus signalling 1; endoplasmic reticulum to nucleus signaling 1; endoplasmic reticulum to nucleus signalling 1; endoplasmic reticulum-to-nucleus signaling 1; Endoribonuclease; ER to nucleus signalling 1; ERN1; FLJ30999; hIRE1p; inositol-requiring 1; inositol-requiring 1 alpha; inositol-requiring enzyme 1; inositol-requiring protein 1; IRE1; IRE1a; IRE1a antibody; Ire1alpha; Ire1-alpha; Ire1p; IRE1p antibody; MGC163277; MGC163279; protein kinase/endoribonuclease; RGD1559716; Serine/threonine-protein kinase; Serine/threonine-protein kinase/endoribonuclease IRE1; serine/threonine-protein kinase/endoribonuclease IRE1-like

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2081, 498013, 78943

Content And Storage:
4° C, store in dark

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.2 mg/mL

Formulation:
50mM sodium borate with no preservative

Gene Accession No.:
O75460, Q9EQY0

Gene Symbols:
ERN1

Immunogen:
A synthetic peptide within the human IRE1 alpha protein (within residues 700-800).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA522727

--


Antigen:
IRE1 alpha

Classification:
Polyclonal

Conjugate:
HRP

Gene:
ERN1

Gene Alias:
9030414B18Rik; AI225830; C85377; endoplasmic reticulum (ER) to nucleus signalling 1; endoplasmic reticulum to nucleus signaling 1; endoplasmic reticulum to nucleus signalling 1; endoplasmic reticulum-to-nucleus signaling 1; Endoribonuclease; ER to nucleus signalling 1; ERN1; FLJ30999; hIRE1p; inositol-requiring 1; inositol-requiring 1 alpha; inositol-requiring enzyme 1; inositol-requiring protein 1; IRE1; IRE1a; IRE1a antibody; Ire1alpha; Ire1-alpha; Ire1p; IRE1p antibody; MGC163277; MGC163279; protein kinase/endoribonuclease; RGD1559716; Serine/threonine-protein kinase; Serine/threonine-protein kinase/endoribonuclease IRE1; serine/threonine-protein kinase/endoribonuclease IRE1-like

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2081, 498013, 78943

Content And Storage:
4° C, store in dark

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.88 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
O75460, Q9EQY0

Gene Symbols:
ERN1

Immunogen:
A synthetic peptide within the human IRE1 alpha protein (within residues 700-800).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA522729

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Antigen:
LC3A/LC3B

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
MAP1LC3B2

Gene Alias:
1010001C15Rik; 1010001H21Rik; 4922501H04Rik; Atg8; ATG8E; ATG8F; Autophagy-related protein LC3 A; autophagy-related protein LC3 B; Autophagy-related ubiquitin-like modifier LC3 A; autophagy-related ubiquitin-like modifier LC3 B; LC3; LC3a; LC3b; MAP1 light chain 3-like protein 1; MAP1 light chain 3-like protein 2; MAP1A/1B light chain 3 A; MAP1A/1B light chain 3 B; MAP1A/1BLC3; MAP1A/MAP1B LC3 A; MAP1A/MAP1B LC3 B; MAP1A/MAP1B light chain 3 A; MAP1A/MAP1B light chain 3 B; Map1alc3; MAP1BLC3; Map1lc3; Map1lc3a; MAP1LC3B; MAP1LC3B-a; microtubule associated protein 1 light chain 3 alpha; microtubule associated protein 1 light chain 3 beta; microtubule-associated protein 1 light chain 3; microtubule-associated protein 1 light chain 3 alpha; Microtubule-associated protein 1 light chain 3 beta; microtubule-associated protein 1-light chain 3A; microtubule-associated proteins 1A/1B light chain 3; microtubule-associated proteins 1A/1B light chain 3A; Microtubule-associated proteins 1A/1B light chain 3B; Mpl3; wu:fb60g11; zbs559; zgc:56434; zgc:77094

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100359928, 322425, 362245, 406466, 477201, 479619, 643246, 64862, 66734, 67443, 81631, 84557

Content And Storage:
4° C, store in dark

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.65 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
A6NCE7, Q62625, Q6XVN8, Q91VR7, Q9CQV6, Q9GZQ8, Q9H492

Gene Symbols:
MAP1LC3A, MAP1LC3B, MAP1LC3B2

Immunogen:
A synthetic peptide made to an internal portion of the human LC3 protein sequence (between residues 25-121).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Amphibian, Canine, Fish, Human, Mouse, Plant, Rat, Zebrafish

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA522730

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Antigen:
LC3A/LC3B

Classification:
Polyclonal

Conjugate:
DyLight 650

Gene:
MAP1LC3B2

Gene Alias:
1010001C15Rik; 1010001H21Rik; 4922501H04Rik; Atg8; ATG8E; ATG8F; Autophagy-related protein LC3 A; autophagy-related protein LC3 B; Autophagy-related ubiquitin-like modifier LC3 A; autophagy-related ubiquitin-like modifier LC3 B; LC3; LC3a; LC3b; MAP1 light chain 3-like protein 1; MAP1 light chain 3-like protein 2; MAP1A/1B light chain 3 A; MAP1A/1B light chain 3 B; MAP1A/1BLC3; MAP1A/MAP1B LC3 A; MAP1A/MAP1B LC3 B; MAP1A/MAP1B light chain 3 A; MAP1A/MAP1B light chain 3 B; Map1alc3; MAP1BLC3; Map1lc3; Map1lc3a; MAP1LC3B; MAP1LC3B-a; microtubule associated protein 1 light chain 3 alpha; microtubule associated protein 1 light chain 3 beta; microtubule-associated protein 1 light chain 3; microtubule-associated protein 1 light chain 3 alpha; Microtubule-associated protein 1 light chain 3 beta; microtubule-associated protein 1-light chain 3A; microtubule-associated proteins 1A/1B light chain 3; microtubule-associated proteins 1A/1B light chain 3A; Microtubule-associated proteins 1A/1B light chain 3B; Mpl3; wu:fb60g11; zbs559; zgc:56434; zgc:77094

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100359928, 322425, 362245, 406466, 477201, 479619, 643246, 64862, 66734, 67443, 81631, 84557

Content And Storage:
4° C, store in dark

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.68 mg/mL

Formulation:
50mM sodium borate with 0.05% sodium azide

Gene Accession No.:
A6NCE7, Q62625, Q6XVN8, Q91VR7, Q9CQV6, Q9GZQ8, Q9H492

Gene Symbols:
MAP1LC3A, MAP1LC3B, MAP1LC3B2

Immunogen:
A synthetic peptide made to an internal portion of the human LC3 protein sequence (between residues 25-121).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Amphibian, Canine, Fish, Human, Mouse, Plant, Rat, Zebrafish

Product Type:
Antibody

Isotype:
IgG