PIPA522858

ATG5 Polyclonal Antibody, DyLight™ 550, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA522858-Each-of-1 In Stock ₹ 46,074.06

PIPA522858 - Each of 1

₹ 46,074.06

In Stock

Quantity

1

Base Price: ₹ 46,074.06

GST (18%): ₹ 8,293.331

Total Price: ₹ 54,367.391

Antigen

ATG5

Classification

Polyclonal

Conjugate

DyLight 550

Gene

Atg5

Gene Alias

2010107M05Rik; 3110067M24Rik; APG 5; APG5; APG5 autophagy 5 like (APG5L); APG5 autophagy 5-like protein; APG5 autophagy 5-like protein, isoform 1; APG5L; APG5-LIKE; apoptosis-specific protein; Apoptosis-specific protein (ASP); ASP; atg5; Atg-5; ATG5 autophagy related 5 homolog; ATG5 autophagy related 5 homolog (S. cerevisiae); atg5.L; Atg5l; Atg5-PA; autophagy 5-like protein; autophagy protein 5; autophagy related 5; autophagy related 5 L homeolog; autophagy related 5-like protein; Autophagy-related 5; autophagy-specific gene 5; AW319544; C88337; CG1643; CG1643-PA; DmAtg5; Dmel\CG1643; Dmel_CG1643; hAPG5; hypothetical protein LOC532686; LD34980p; Paddy; XELAEV_18027227mg; zgc:100934

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100735170, 100739102, 11793, 31666, 365601, 443756, 494180, 532686, 641362, 9474

Content And Storage

4° C, store in dark

Form

Liquid

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.70 mg/mL

Formulation

50mM sodium borate with 0.05% sodium azide

Gene Accession No.

Q3MQ04, Q3MQ06, Q3MQ24, Q99J83, Q9H1Y0, Q9W3R7

Gene Symbols

Atg5, atg5.L

Immunogen

A synthetic peptide made to an N-terminal region (within residues 1-50) of the human ATG5 protein.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Bovine, Drosophila, Fish, Guinea Pig, Human, Mouse, Non-human Primate, Porcine, Rat, Reptile, X. laevis, Zebrafish

Product Type

Antibody

Isotype

IgG

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Description

  • In Western Blot, a band is seen ∽56 kDa representing the ATG5-ATG12 complex, the molecular weight of human ATG5 is ∽33 kDa
  • Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended
  • Suggested positive control: mouse wildtype ES cell lysate
  • ATG5 (Autophagy Related 5) is an important element for autophagy and may play an important role in the apoptotic process
  • ATG5 is also involved in other cellular processes that include mitochondrial quality control after oxidative damage, negative regulation of the innate anti-viral immune response, lymphocyte development and proliferation, MHC II antigen presentation, and adipocyte differentiation
  • Following conjugation to ATG12, the conjugate participates in the formation of autophagosome
  • ATG5 contributes to autophagic cell death by interacting with Fas-associated protein with death domain (FADD)
  • The ATG5-ATG12 conjugate forms a cup-shaped isolation membrane that then detaches from the membrane immediately before or after autophagosome formation is completed
  • APG5 may play a role in the apoptotic process, possibly within the modified cytoskeleton
  • Further, APG5 expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity
  • The APG5-APG12 conjugate also associates with innate immune response proteins such as RIG-I and VISA (also known as IPS-1), inhibiting type I interferon production and permitting viral replication in host cells
  • Diseases associated with ATG5 dysfunction include spinocerebellar ataxia.

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PIPA522858

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Antigen:
ATG5

Classification:
Polyclonal

Conjugate:
DyLight 550

Gene:
Atg5

Gene Alias:
2010107M05Rik; 3110067M24Rik; APG 5; APG5; APG5 autophagy 5 like (APG5L); APG5 autophagy 5-like protein; APG5 autophagy 5-like protein, isoform 1; APG5L; APG5-LIKE; apoptosis-specific protein; Apoptosis-specific protein (ASP); ASP; atg5; Atg-5; ATG5 autophagy related 5 homolog; ATG5 autophagy related 5 homolog (S. cerevisiae); atg5.L; Atg5l; Atg5-PA; autophagy 5-like protein; autophagy protein 5; autophagy related 5; autophagy related 5 L homeolog; autophagy related 5-like protein; Autophagy-related 5; autophagy-specific gene 5; AW319544; C88337; CG1643; CG1643-PA; DmAtg5; Dmel\CG1643; Dmel_CG1643; hAPG5; hypothetical protein LOC532686; LD34980p; Paddy; XELAEV_18027227mg; zgc:100934

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100735170, 100739102, 11793, 31666, 365601, 443756, 494180, 532686, 641362, 9474

Content And Storage:
4° C, store in dark

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.70 mg/mL

Formulation:
50mM sodium borate with 0.05% sodium azide

Gene Accession No.:
Q3MQ04, Q3MQ06, Q3MQ24, Q99J83, Q9H1Y0, Q9W3R7

Gene Symbols:
Atg5, atg5.L

Immunogen:
A synthetic peptide made to an N-terminal region (within residues 1-50) of the human ATG5 protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Drosophila, Fish, Guinea Pig, Human, Mouse, Non-human Primate, Porcine, Rat, Reptile, X. laevis, Zebrafish

Product Type:
Antibody

Isotype:
IgG

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PIPA522864

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Antigen:
VMAT2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SLC18A2

Gene Alias:
1110037L13Rik; 9330105E13; MGC120477; MGC120478; MGC26538; MNAT; monoamine neurotransmitter transporter; monoamine transporter; SLC18A2; solute carrier family 18 (vesicular monoamine transporter), member 2; solute carrier family 18 (vesicular monoamine), member 2; Solute carrier family 18 A2 (vesicular monoamine transporter 2); solute carrier family 18 member 2; solute carrier family 18 member A2; solute carrier family 18, member 2; Svat; SVMT; synaptic vesicular amine transporter; VAT2; vesicle monoamine transporter type 2; vesicle monoamine/H+ antiporter; vesicular amine transporter 2; vesicular monoamine transporter 2; VMAT2; VMAT-2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100351780, 214084, 25549, 6571

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q01827, Q05940, Q8BRU6

Gene Symbols:
SLC18A2

Immunogen:
Reacts with an internal sequence of the human, mouse and rat VMAT2 protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA522865

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Antigen:
Aquaporin 2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Aqp2

Gene Alias:
ADH water channel; AQP 2; AQP CD; Aqp2; AQP-2; AQPCD; AQP-CD; aquaporin 2; aquaporin 2 (collecting duct); Aquaporin CD; Aquaporin2; aquaporin-2; Aquaporin-CD; Aquaporine 2; collecting duct water channel protein; cph; jpk; MGC34501; Water channel protein for renal collecting duct; water-channel aquaporin 2; WCH CD; WCHCD; WCH-CD

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11827, 25386, 359

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P34080, P41181, P56402

Gene Symbols:
Aqp2

Immunogen:
Synthetic peptide made to a C-terminus portion of the rat protein (within residues 200-300).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA522876

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Antigen:
TRPM2

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
TRPM2

Gene Alias:
9830168K16Rik; C79133; EC 3.6.1.13; EREG 1; EREG1; Estrogen-responsive element-associated gene 1 protein; KNP 3; KNP3; Long transient receptor potential channel 2; LTRPC 2; LTRPC2; LTrpC-2; MGC133383; NUDT9H; NUDT9L1; null; transient receptor potential cation channel subfamily M member 2; transient receptor potential cation channel, subfamily M, member 2; transient receptor potential channel 7; Transient receptor potential melastatin 2; transient receptor potential melastatin family 2; transient receptor protein 7; Trp7; TRPC 7; TRPC7; TRPM 2; Trpm2; Trpm2-predicted; Trrp7

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
28240, 294329

Content And Storage:
4° C, store in dark

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot

Concentration:
0.82 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
E9PTA2, Q91YD4

Gene Symbols:
TRPM2

Immunogen:
Synthetic peptide made to a C-terminal portion of the rat protein (within residues 1430-1508).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG