PIPA523095

TRAIL-R2 (DR5) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA523095-Each-of-1 In Stock ₹ 47,015.22

PIPA523095 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

TRAIL-R2 (DR5)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TNFRSF10B

Gene Alias

apoptosis inducing protein TRICK2A/2B; apoptosis inducing receptor TRAIL-R2; CD262; cytotoxic TRAIL receptor-2; death domain containing receptor for TRAIL/Apo-2L; death receptor 5; Dr5; dr-5; Fas-like protein; KILLER; KILLER/DR5; KILLER/DR5 TRAIL death-inducing receptor; Ly98; MK; p53-regulated DNA damage-inducible cell death receptor(killer); sCD262; soluble CD262; TNF receptor superfamily member 10b; TNF-related apoptosis-inducing ligand receptor 2; TNFRSF10B; TRAIL receptor 2; TRAILR2; TRAIL-R2; TRICK2; TRICK2A; TRICK2B; TRICKB; tumor necrosis factor receptor superfamily member 10B; tumor necrosis factor receptor superfamily, member 10b; tumor necrosis factor receptor-like protein ZTNFR9; UNQ160/PRO186; ZTNFR9

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

21933, 8795

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1.0 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

O14763, Q9QZM4

Gene Symbols

TNFRSF10B

Immunogen

Synthetic peptide (388 CKWVNKTGRDASVHTLLDALE 407) of DR5/TRAILR2 protein.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • PA5-23095 targets DR5/TRAILR2 in FACS, ICC, IF, IHC (P), and WB applications and shows reactivity with Human samples
  • The PA5-23095 immunogen is synthetic peptide (388 CKWVNKTGRDASVHTLLDALE 407) of DR5/TRAILR2 protein
  • DR5 (Apo2, TRAIL-R2, TRICK2, KILLER) is a recently identified death domain containing receptor for TRAIL, which mediates TRAIL induced apoptosis
  • DR5 is a member of the TNF-receptor superfamily, and contains an intracellular death domain
  • DR5 can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal
  • Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by DR5
  • Two transcript variants encoding different isoforms of DR5 and one non-coding transcript have been found
  • Overexpression of DR5 induces apoptosis and activates NF-kappa-B
  • DR5 is expressed in a number of cell types, and to particularly high levels in lymphocytes and spleen
  • Diseases associated with DR5 dysfunction include squamous cell carcinoma, and diffuse infiltrative lymphocytosis syndrome.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA523095

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Antigen:
TRAIL-R2 (DR5)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TNFRSF10B

Gene Alias:
apoptosis inducing protein TRICK2A/2B; apoptosis inducing receptor TRAIL-R2; CD262; cytotoxic TRAIL receptor-2; death domain containing receptor for TRAIL/Apo-2L; death receptor 5; Dr5; dr-5; Fas-like protein; KILLER; KILLER/DR5; KILLER/DR5 TRAIL death-inducing receptor; Ly98; MK; p53-regulated DNA damage-inducible cell death receptor(killer); sCD262; soluble CD262; TNF receptor superfamily member 10b; TNF-related apoptosis-inducing ligand receptor 2; TNFRSF10B; TRAIL receptor 2; TRAILR2; TRAIL-R2; TRICK2; TRICK2A; TRICK2B; TRICKB; tumor necrosis factor receptor superfamily member 10B; tumor necrosis factor receptor superfamily, member 10b; tumor necrosis factor receptor-like protein ZTNFR9; UNQ160/PRO186; ZTNFR9

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
21933, 8795

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
O14763, Q9QZM4

Gene Symbols:
TNFRSF10B

Immunogen:
Synthetic peptide (388 CKWVNKTGRDASVHTLLDALE 407) of DR5/TRAILR2 protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA523103

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Antigen:
TLR11

Classification:
Polyclonal

Conjugate:
FITC

Gene:
Tlr11

Gene Alias:
Gm1365; Gm287; RGD1564460; RP23-392K10.4; Tlr11; Tlr12; Toll-like receptor 11; Toll-like receptor 12

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
239081, 498491

Content And Storage:
4° C, store in dark

Form:
Liquid

Applications:
Flow Cytometry

Concentration:
0.81 mg/mL

Formulation:
50mM sodium borate with 0.05% sodium azide

Gene Accession No.:
Q6R5P0

Gene Symbols:
Tlr11

Immunogen:
Synthetic peptide (amino acids 911-926) of TLR11 protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA523105

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Antigen:
TLR3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TLR3

Gene Alias:
AI957183; CD283; IIAE2; TLR 3; TLR3; TLR-3; toll like receptor 3; toll-like receptor 3; toll-like receptor 3 variant 1

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
100037937, 142980, 7098

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Dot Blot, Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
O15455, Q99MB1

Gene Symbols:
TLR3

Immunogen:
A mix of synthetic peptides corresponding to amino acids 135-150, 828-844, and 876-891 of TLR3/CD283 protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Porcine

Product Type:
Antibody

Isotype:
IgG

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PIPA523112

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Antigen:
RGS18

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RGS18

Gene Alias:
regulator of G-protein signaling 18; regulator of G-protein signalling 13; regulator of G-protein signalling 18; RGS13; RGS18; RP11-142L4.1

Host Species:
Rabbit

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
64214, 64407

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 50% glycerol and 0.025% sodium azide

Gene Accession No.:
Q99PG4, Q9NS28

Gene Symbols:
RGS18

Immunogen:
Within the range of amino acids 30-62 of human RGS18 protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG